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• W2087428144 abstract "Changes that occur in the local draining lymph nodes including, changes in cell surface markers and cytokine gene expression were studied over the first 4 weeks of a primary, Ostertagia ostertagi infection of the abomasum. Cells recovered from the abomasal lymph nodes (ABLN) after infection showed a decrease in the percentage of CD3+ cells, and an increase in the percentage of IgM+ cells and cells bearing the TcR1 marker. These changes were coincident with an increase in the proportion of activated cells (II-2R). Analysis of mitogen-stimulated ABLN cells by RNase protection assay (RPA) showed a dramatic reduction in IL-2 and IFN-gamma transcription after infection. In addition, analysis of unstimulated ABLN cells by competitive RT-PCR showed a similar decrease in demonstrable levels of IL-2 mRNA, but IL-10, IL-4 and IFN-gamma mRNA levels were elevated." @default.
• W2087428144 created "2016-06-24" @default.
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• W2087428144 date "1997-08-01" @default.
• W2087428144 modified "2023-09-29" @default.
• W2087428144 title "Cytokine profile induced by a primary infection with Ostertagia ostertagi in cattle" @default.
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• W2087428144 doi "https://doi.org/10.1016/s0165-2427(96)05775-3" @default.
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