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- W2087484450 abstract "Synthesis of the 8-amino-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine ring system was accomplished by intramolecular cyclization of an iminium ion, derived from condensation of an amine and a substituted γ-(1-imidazolyl)butyraldehyde. The reaction was used to produce conformationally restricted farnesyltransferase inhibitor analogues which exhibit improved in vivo metabolic stability." @default.
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- W2087484450 date "2000-10-10" @default.
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- W2087484450 title "Synthesis of Conformationally Constrained 5,6,7,8-Tetrahydroimidazo[1,5-<i>a</i>]pyridine Inhibitors of Farnesyltransferase" @default.
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- W2087484450 doi "https://doi.org/10.1021/ol0002424" @default.
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