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• W2087514523 abstract "Transcription of the thrU(tufB) operon is trans-activated by the protein FIS which binds to the promoter upstream activator sequence (UAS). Deletions of parts of the UAS and insertions show that optimal trans-activation requires occupation by FIS of the two FIS-binding regions on the UAS and specific helical positioning of these regions. On the basis of these and other data, a model for the mechanism of thrU(tufB) trans-activation by FIS is proposed. This model implies that the mechanisms underlying stimulation by FIS of two totally different processes: inversion of viral DNA segments and transcription of stable RNA operons, are essentially the same." @default.
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• W2087514523 date "1992-01-01" @default.
• W2087514523 modified "2023-09-23" @default.
• W2087514523 title "The Mechanism of trans-activation of the Escherichia coli operon thru(tufB) by the protein FIS. A Model" @default.
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• W2087514523 doi "https://doi.org/10.1093/nar/20.15.4077" @default.
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