Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087526860> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2087526860 endingPage "432" @default.
- W2087526860 startingPage "423" @default.
- W2087526860 abstract "Abstract We have carried out experiments designed to investigate the molecular mechanism by which the cI protein of phage λ functions as a repressor of RNA synthesis catalyzed by the host RNA polymerase. We find that the cI protein can inhibit RNA synthesis if added before RNA polymerase binds to λ DNA, after RNA polymerase binds, or even after formation of an “initiated complex” by the addition of ATP and GTP. However, prior binding of cI protein appears to prevent formation of an initiated complex by RNA polymerase. From these results, we suggest that the cI protein may have the capacity to inhibit two stages of the RNA polymerase reaction: formation of a stable initiated complex if repressor is bound before polymerase; or, an early stage of RNA synthesis subsequent to formation of an initiated complex if polymerase is bound before repressor. The possible biological merit of such a dual mechanism is discussed." @default.
- W2087526860 created "2016-06-24" @default.
- W2087526860 creator A5003978072 @default.
- W2087526860 creator A5025770436 @default.
- W2087526860 creator A5043368447 @default.
- W2087526860 date "1972-06-01" @default.
- W2087526860 modified "2023-09-27" @default.
- W2087526860 title "Repression by the cI protein of phage λ: Interaction with RNA polymerase" @default.
- W2087526860 cites W1977652146 @default.
- W2087526860 cites W1986014475 @default.
- W2087526860 cites W1991355308 @default.
- W2087526860 cites W2047330388 @default.
- W2087526860 cites W2070070246 @default.
- W2087526860 cites W2181183219 @default.
- W2087526860 doi "https://doi.org/10.1016/0022-2836(72)90460-3" @default.
- W2087526860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5045306" @default.
- W2087526860 hasPublicationYear "1972" @default.
- W2087526860 type Work @default.
- W2087526860 sameAs 2087526860 @default.
- W2087526860 citedByCount "18" @default.
- W2087526860 crossrefType "journal-article" @default.
- W2087526860 hasAuthorship W2087526860A5003978072 @default.
- W2087526860 hasAuthorship W2087526860A5025770436 @default.
- W2087526860 hasAuthorship W2087526860A5043368447 @default.
- W2087526860 hasConcept C104317684 @default.
- W2087526860 hasConcept C150194340 @default.
- W2087526860 hasConcept C153911025 @default.
- W2087526860 hasConcept C185592680 @default.
- W2087526860 hasConcept C186310378 @default.
- W2087526860 hasConcept C2776449523 @default.
- W2087526860 hasConcept C54355233 @default.
- W2087526860 hasConcept C552990157 @default.
- W2087526860 hasConcept C67705224 @default.
- W2087526860 hasConcept C70721500 @default.
- W2087526860 hasConcept C82381507 @default.
- W2087526860 hasConcept C86803240 @default.
- W2087526860 hasConcept C95444343 @default.
- W2087526860 hasConceptScore W2087526860C104317684 @default.
- W2087526860 hasConceptScore W2087526860C150194340 @default.
- W2087526860 hasConceptScore W2087526860C153911025 @default.
- W2087526860 hasConceptScore W2087526860C185592680 @default.
- W2087526860 hasConceptScore W2087526860C186310378 @default.
- W2087526860 hasConceptScore W2087526860C2776449523 @default.
- W2087526860 hasConceptScore W2087526860C54355233 @default.
- W2087526860 hasConceptScore W2087526860C552990157 @default.
- W2087526860 hasConceptScore W2087526860C67705224 @default.
- W2087526860 hasConceptScore W2087526860C70721500 @default.
- W2087526860 hasConceptScore W2087526860C82381507 @default.
- W2087526860 hasConceptScore W2087526860C86803240 @default.
- W2087526860 hasConceptScore W2087526860C95444343 @default.
- W2087526860 hasIssue "3" @default.
- W2087526860 hasLocation W20875268601 @default.
- W2087526860 hasLocation W20875268602 @default.
- W2087526860 hasOpenAccess W2087526860 @default.
- W2087526860 hasPrimaryLocation W20875268601 @default.
- W2087526860 hasRelatedWork W1528399183 @default.
- W2087526860 hasRelatedWork W1659766963 @default.
- W2087526860 hasRelatedWork W1882082207 @default.
- W2087526860 hasRelatedWork W1989149131 @default.
- W2087526860 hasRelatedWork W2023767520 @default.
- W2087526860 hasRelatedWork W2063381905 @default.
- W2087526860 hasRelatedWork W2074484440 @default.
- W2087526860 hasRelatedWork W2131907796 @default.
- W2087526860 hasRelatedWork W2306656032 @default.
- W2087526860 hasRelatedWork W34571489 @default.
- W2087526860 hasVolume "67" @default.
- W2087526860 isParatext "false" @default.
- W2087526860 isRetracted "false" @default.
- W2087526860 magId "2087526860" @default.
- W2087526860 workType "article" @default.