FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087625544> ?p ?o ?g. }

• W2087625544 endingPage "109" @default.
• W2087625544 startingPage "100" @default.
• W2087625544 abstract "Bundling of neurite extensions occur during nerve development and regeneration. Understanding the factors that drive neurite bundling is important for designing biomaterials for nerve regeneration toward the innervation target and preventing nociceptive collateral sprouting. High-density neuron cultures including dorsal root ganglia explants are employed for in vitro screening of biomaterials designed to control directional outgrowth. Although some semi-automated image processing methods exist for quantification of neurite outgrowth, methods to quantify axonal fasciculation in terms of direction of neurite outgrowth are lacking. This work presents a semi-automated program to analyze micrographs of high-density neurites; the program aims to quantify axonal fasciculation by determining the orientational distribution function of the tangent vectors of the neurites and calculating its Fourier series coefficients (‘c’ values). We found that neurite directional distribution analysis (NDDA) of fasciculated neurites yielded ‘c’ values of ≥∼0.25 whereas branched outgrowth led to statistically significant lesser values of <∼0.2. The ‘c’ values correlated directly to the width of neurite bundles and indirectly to the number of branching points. Information about the directional distribution of outgrowth is lost in simple counting methods or achieved laboriously through manual analysis. The NDDA supplements previous quantitative analyses of axonal bundling using a vector-based approach that captures new information about the directionality of outgrowth. The NDDA is a valuable addition to open source image processing tools available to biomedical researchers offering a robust, precise approach to quantification of imaged features important in tissue development, disease, and repair." @default.
• W2087625544 created "2016-06-24" @default.
• W2087625544 creator A5005125241 @default.
• W2087625544 creator A5012511525 @default.
• W2087625544 creator A5030749967 @default.
• W2087625544 creator A5057871048 @default.
• W2087625544 creator A5058372263 @default.
• W2087625544 date "2014-05-01" @default.
• W2087625544 modified "2023-09-23" @default.
• W2087625544 title "Semi-automatic quantification of neurite fasciculation in high-density neurite images by the neurite directional distribution analysis (NDDA)" @default.
• W2087625544 cites W1582166679 @default.
• W2087625544 cites W1648699603 @default.
• W2087625544 cites W1964441207 @default.
• W2087625544 cites W1965904253 @default.
• W2087625544 cites W1974525801 @default.
• W2087625544 cites W1974902416 @default.
• W2087625544 cites W1983794951 @default.
• W2087625544 cites W1984509666 @default.
• W2087625544 cites W1988239991 @default.
• W2087625544 cites W1989289921 @default.
• W2087625544 cites W1992033348 @default.
• W2087625544 cites W1998397185 @default.
• W2087625544 cites W1998514529 @default.
• W2087625544 cites W2003653107 @default.
• W2087625544 cites W2005978154 @default.
• W2087625544 cites W2009384522 @default.
• W2087625544 cites W2011840588 @default.
• W2087625544 cites W2013865460 @default.
• W2087625544 cites W2017323918 @default.
• W2087625544 cites W2019575274 @default.
• W2087625544 cites W2024405375 @default.
• W2087625544 cites W2029912651 @default.
• W2087625544 cites W2032322171 @default.
• W2087625544 cites W2033710513 @default.
• W2087625544 cites W2037230002 @default.
• W2087625544 cites W2045747193 @default.
• W2087625544 cites W2059278194 @default.
• W2087625544 cites W2063874859 @default.
• W2087625544 cites W2066196783 @default.
• W2087625544 cites W2066427639 @default.
• W2087625544 cites W2068012178 @default.
• W2087625544 cites W2071670230 @default.
• W2087625544 cites W2076763936 @default.
• W2087625544 cites W2079880925 @default.
• W2087625544 cites W2080306322 @default.
• W2087625544 cites W2084924803 @default.
• W2087625544 cites W2085103168 @default.
• W2087625544 cites W2085499204 @default.
• W2087625544 cites W2086555840 @default.
• W2087625544 cites W2087420052 @default.
• W2087625544 cites W2088056286 @default.
• W2087625544 cites W2088686740 @default.
• W2087625544 cites W2090036201 @default.
• W2087625544 cites W2094278270 @default.
• W2087625544 cites W2094520929 @default.
• W2087625544 cites W2094644814 @default.
• W2087625544 cites W2095407896 @default.
• W2087625544 cites W2096130846 @default.
• W2087625544 cites W2100169867 @default.
• W2087625544 cites W2127960034 @default.
• W2087625544 cites W2132795777 @default.
• W2087625544 cites W2141695741 @default.
• W2087625544 cites W2144797754 @default.
• W2087625544 cites W2148519596 @default.
• W2087625544 cites W2153287457 @default.
• W2087625544 cites W2156612477 @default.
• W2087625544 cites W2158456505 @default.
• W2087625544 cites W2162828427 @default.
• W2087625544 cites W2164897127 @default.
• W2087625544 cites W2167401672 @default.
• W2087625544 cites W2168687312 @default.
• W2087625544 cites W2169931542 @default.
• W2087625544 cites W2279313673 @default.
• W2087625544 cites W2319662446 @default.
• W2087625544 doi "https://doi.org/10.1016/j.jneumeth.2014.03.006" @default.
• W2087625544 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4057284" @default.
• W2087625544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24680908" @default.
• W2087625544 hasPublicationYear "2014" @default.
• W2087625544 type Work @default.
• W2087625544 sameAs 2087625544 @default.
• W2087625544 citedByCount "2" @default.
• W2087625544 countsByYear W20876255442015 @default.
• W2087625544 countsByYear W20876255442021 @default.
• W2087625544 crossrefType "journal-article" @default.
• W2087625544 hasAuthorship W2087625544A5005125241 @default.
• W2087625544 hasAuthorship W2087625544A5012511525 @default.
• W2087625544 hasAuthorship W2087625544A5030749967 @default.
• W2087625544 hasAuthorship W2087625544A5057871048 @default.
• W2087625544 hasAuthorship W2087625544A5058372263 @default.
• W2087625544 hasBestOaLocation W20876255442 @default.
• W2087625544 hasConcept C113246987 @default.
• W2087625544 hasConcept C135903288 @default.
• W2087625544 hasConcept C136229726 @default.
• W2087625544 hasConcept C169760540 @default.
• W2087625544 hasConcept C186060115 @default.
• W2087625544 hasConcept C202751555 @default.
• W2087625544 hasConcept C2778970341 @default.
• W2087625544 hasConcept C2779530196 @default.

• next