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- W2087667588 abstract "The Q genes of phages lambda and 82 encode transcription antiterminators that are active in vitro in a purified transcription system. Transcription termination is thought to involve two distinct steps: pausing of the transcription complex at the terminator and release of enzyme and RNA; either or both steps might be inhibited by Q protein. We show that Q-modified RNA polymerase pauses much less efficiently than does unmodified enzyme at the natural pause sites of a rho-dependent terminator as well as at other pause sites. This changed behavior can account for the termination properties of Q-modified RNA polymerase and reflects a fundamental alteration of the elongation properties of the enzyme." @default.
- W2087667588 created "2016-06-24" @default.
- W2087667588 creator A5002110077 @default.
- W2087667588 creator A5082698015 @default.
- W2087667588 date "1989-07-01" @default.
- W2087667588 modified "2023-10-04" @default.
- W2087667588 title "Gene Q antiterminator proteins of Escherichia coli phages 82 and lambda suppress pausing by RNA polymerase at a rho-dependent terminator and at other sites." @default.
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- W2087667588 doi "https://doi.org/10.1073/pnas.86.14.5301" @default.
- W2087667588 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/297609" @default.
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