FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087675416> ?p ?o ?g. }

• W2087675416 abstract "Recently, we crossed an original haired RET-transgenic mouse of line 242 with a hairless mouse and established a hairless RET-(HL/RET)-transgenic mouse line (242-hr/hr) with hyperpigmented skin but no tumors. In this study, we examined the effect of hyperpigmented skin in HL/RET-transgenic mice on UV irradiation-mediated cutaneous cancer development. UV irradiation to this mouse line never induced melanoma despite the presence of melanoma-inducible transgenic RET oncogenes. On the contrary, the hyperpigmented skin efficiently protected UV-mediated squamous carcinoma development in the skin. Probably underlying this result, hyperpigmentation protected the skin from damage and blocked the accompanying signal transduction for tyrosine phosphorylation of multiple cellular proteins and activation/phosphorylation of extracellular signal-regulated, c-Jun N-terminal, and p38 kinases. Thus, we demonstrated hyperpigmentation-mediated in vivo protection against UV irradiation-induced skin cancer." @default.
• W2087675416 created "2016-06-24" @default.
• W2087675416 creator A5010839188 @default.
• W2087675416 creator A5025405266 @default.
• W2087675416 creator A5034433475 @default.
• W2087675416 creator A5048038268 @default.
• W2087675416 creator A5048991469 @default.
• W2087675416 creator A5054474804 @default.
• W2087675416 creator A5054753108 @default.
• W2087675416 creator A5059264521 @default.
• W2087675416 creator A5063960911 @default.
• W2087675416 creator A5069490450 @default.
• W2087675416 creator A5073952817 @default.
• W2087675416 creator A5089988781 @default.
• W2087675416 date "2007-05-01" @default.
• W2087675416 modified "2023-09-28" @default.
• W2087675416 title "Protective Effect of Hyperpigmented Skin on UV-Mediated Cutaneous Cancer Development" @default.
• W2087675416 cites W1629158872 @default.
• W2087675416 cites W1974271424 @default.
• W2087675416 cites W1985975702 @default.
• W2087675416 cites W2005580242 @default.
• W2087675416 cites W2012141473 @default.
• W2087675416 cites W2015756738 @default.
• W2087675416 cites W2019239936 @default.
• W2087675416 cites W2031492533 @default.
• W2087675416 cites W2031859419 @default.
• W2087675416 cites W2032421088 @default.
• W2087675416 cites W2058709111 @default.
• W2087675416 cites W2071749936 @default.
• W2087675416 cites W2086390568 @default.
• W2087675416 cites W2100196851 @default.
• W2087675416 cites W2106211503 @default.
• W2087675416 cites W2106770504 @default.
• W2087675416 cites W2116415841 @default.
• W2087675416 cites W2117199571 @default.
• W2087675416 cites W2131533236 @default.
• W2087675416 cites W2131784395 @default.
• W2087675416 cites W2138959209 @default.
• W2087675416 cites W2157222323 @default.
• W2087675416 doi "https://doi.org/10.1038/sj.jid.5700659" @default.
• W2087675416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17159911" @default.
• W2087675416 hasPublicationYear "2007" @default.
• W2087675416 type Work @default.
• W2087675416 sameAs 2087675416 @default.
• W2087675416 citedByCount "24" @default.
• W2087675416 countsByYear W20876754162012 @default.
• W2087675416 countsByYear W20876754162014 @default.
• W2087675416 countsByYear W20876754162015 @default.
• W2087675416 countsByYear W20876754162016 @default.
• W2087675416 countsByYear W20876754162017 @default.
• W2087675416 countsByYear W20876754162018 @default.
• W2087675416 countsByYear W20876754162019 @default.
• W2087675416 countsByYear W20876754162020 @default.
• W2087675416 crossrefType "journal-article" @default.
• W2087675416 hasAuthorship W2087675416A5010839188 @default.
• W2087675416 hasAuthorship W2087675416A5025405266 @default.
• W2087675416 hasAuthorship W2087675416A5034433475 @default.
• W2087675416 hasAuthorship W2087675416A5048038268 @default.
• W2087675416 hasAuthorship W2087675416A5048991469 @default.
• W2087675416 hasAuthorship W2087675416A5054474804 @default.
• W2087675416 hasAuthorship W2087675416A5054753108 @default.
• W2087675416 hasAuthorship W2087675416A5059264521 @default.
• W2087675416 hasAuthorship W2087675416A5063960911 @default.
• W2087675416 hasAuthorship W2087675416A5069490450 @default.
• W2087675416 hasAuthorship W2087675416A5073952817 @default.
• W2087675416 hasAuthorship W2087675416A5089988781 @default.
• W2087675416 hasBestOaLocation W20876754161 @default.
• W2087675416 hasConcept C102230213 @default.
• W2087675416 hasConcept C104317684 @default.
• W2087675416 hasConcept C11960822 @default.
• W2087675416 hasConcept C121608353 @default.
• W2087675416 hasConcept C126322002 @default.
• W2087675416 hasConcept C141035611 @default.
• W2087675416 hasConcept C142724271 @default.
• W2087675416 hasConcept C16005928 @default.
• W2087675416 hasConcept C184235292 @default.
• W2087675416 hasConcept C2776728111 @default.
• W2087675416 hasConcept C2777459323 @default.
• W2087675416 hasConcept C2777658100 @default.
• W2087675416 hasConcept C2777789703 @default.
• W2087675416 hasConcept C2779156968 @default.
• W2087675416 hasConcept C2909381827 @default.
• W2087675416 hasConcept C502942594 @default.
• W2087675416 hasConcept C54355233 @default.
• W2087675416 hasConcept C55493867 @default.
• W2087675416 hasConcept C555283112 @default.
• W2087675416 hasConcept C62478195 @default.
• W2087675416 hasConcept C71924100 @default.
• W2087675416 hasConcept C86803240 @default.
• W2087675416 hasConcept C95444343 @default.
• W2087675416 hasConceptScore W2087675416C102230213 @default.
• W2087675416 hasConceptScore W2087675416C104317684 @default.
• W2087675416 hasConceptScore W2087675416C11960822 @default.
• W2087675416 hasConceptScore W2087675416C121608353 @default.
• W2087675416 hasConceptScore W2087675416C126322002 @default.
• W2087675416 hasConceptScore W2087675416C141035611 @default.
• W2087675416 hasConceptScore W2087675416C142724271 @default.
• W2087675416 hasConceptScore W2087675416C16005928 @default.
• W2087675416 hasConceptScore W2087675416C184235292 @default.
• W2087675416 hasConceptScore W2087675416C2776728111 @default.

• next