Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087753711> ?p ?o ?g. }
- W2087753711 endingPage "253" @default.
- W2087753711 startingPage "250" @default.
- W2087753711 abstract "Dysfunctions in serotonin neurotransmission have been implicated in some psychiatric disorders, and in particular, altered serotonin transporter function has been noted in panic disorder. In this study, the authors compared platelet [3H]serotonin uptake parameters, including maximum velocities (Vmax) and affinity constants (Km), in patients with panic disorder not undergoing treatment (n = 21) and in healthy subjects (n = 20). Vmax and Km values were re-examined after 12 weeks of paroxetine treatment. Values of Vmax and Km were lower in panic disorder patients at baseline than in healthy subjects. After treatment, Km normalized in panic patients, whereas Vmax did not change. A significant inverse correlation was found between increased Km and changes in anxiety levels. These results support a hypothesis of serotonergic transporter abnormalities in panic disorder, and suggest that increased Km values of platelet serotonin transporters parallel clinical improvement after short-term pharmacotherapy in panic disorder." @default.
- W2087753711 created "2016-06-24" @default.
- W2087753711 creator A5006865930 @default.
- W2087753711 creator A5021419436 @default.
- W2087753711 creator A5023656997 @default.
- W2087753711 creator A5035534489 @default.
- W2087753711 creator A5064360887 @default.
- W2087753711 creator A5069325751 @default.
- W2087753711 date "2010-04-01" @default.
- W2087753711 modified "2023-09-27" @default.
- W2087753711 title "Platelet serotonin transporter function after short-term paroxetine treatment in patients with panic disorder" @default.
- W2087753711 cites W10734341 @default.
- W2087753711 cites W1977943321 @default.
- W2087753711 cites W1982695729 @default.
- W2087753711 cites W1988612597 @default.
- W2087753711 cites W1989107032 @default.
- W2087753711 cites W1997326317 @default.
- W2087753711 cites W2003519496 @default.
- W2087753711 cites W2019763316 @default.
- W2087753711 cites W2019939591 @default.
- W2087753711 cites W2022328784 @default.
- W2087753711 cites W2023578523 @default.
- W2087753711 cites W2030116593 @default.
- W2087753711 cites W2037305317 @default.
- W2087753711 cites W2041985606 @default.
- W2087753711 cites W2043779522 @default.
- W2087753711 cites W2044335206 @default.
- W2087753711 cites W2044633941 @default.
- W2087753711 cites W2081526164 @default.
- W2087753711 cites W2082517699 @default.
- W2087753711 cites W2086901170 @default.
- W2087753711 cites W2091059631 @default.
- W2087753711 cites W2106095564 @default.
- W2087753711 cites W2114613490 @default.
- W2087753711 cites W2124549431 @default.
- W2087753711 cites W2137568489 @default.
- W2087753711 cites W2138643911 @default.
- W2087753711 cites W2160070901 @default.
- W2087753711 cites W2318263888 @default.
- W2087753711 cites W2322803374 @default.
- W2087753711 cites W2401865675 @default.
- W2087753711 cites W2416624752 @default.
- W2087753711 cites W2021354709 @default.
- W2087753711 doi "https://doi.org/10.1016/j.psychres.2008.12.007" @default.
- W2087753711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20207008" @default.
- W2087753711 hasPublicationYear "2010" @default.
- W2087753711 type Work @default.
- W2087753711 sameAs 2087753711 @default.
- W2087753711 citedByCount "6" @default.
- W2087753711 countsByYear W20877537112012 @default.
- W2087753711 countsByYear W20877537112013 @default.
- W2087753711 countsByYear W20877537112015 @default.
- W2087753711 countsByYear W20877537112018 @default.
- W2087753711 crossrefType "journal-article" @default.
- W2087753711 hasAuthorship W2087753711A5006865930 @default.
- W2087753711 hasAuthorship W2087753711A5021419436 @default.
- W2087753711 hasAuthorship W2087753711A5023656997 @default.
- W2087753711 hasAuthorship W2087753711A5035534489 @default.
- W2087753711 hasAuthorship W2087753711A5064360887 @default.
- W2087753711 hasAuthorship W2087753711A5069325751 @default.
- W2087753711 hasConcept C118552586 @default.
- W2087753711 hasConcept C126322002 @default.
- W2087753711 hasConcept C134018914 @default.
- W2087753711 hasConcept C15744967 @default.
- W2087753711 hasConcept C170493617 @default.
- W2087753711 hasConcept C2775864247 @default.
- W2087753711 hasConcept C2776317618 @default.
- W2087753711 hasConcept C2777529043 @default.
- W2087753711 hasConcept C2777828372 @default.
- W2087753711 hasConcept C2778897192 @default.
- W2087753711 hasConcept C2780712732 @default.
- W2087753711 hasConcept C2908747647 @default.
- W2087753711 hasConcept C37000724 @default.
- W2087753711 hasConcept C558461103 @default.
- W2087753711 hasConcept C71924100 @default.
- W2087753711 hasConceptScore W2087753711C118552586 @default.
- W2087753711 hasConceptScore W2087753711C126322002 @default.
- W2087753711 hasConceptScore W2087753711C134018914 @default.
- W2087753711 hasConceptScore W2087753711C15744967 @default.
- W2087753711 hasConceptScore W2087753711C170493617 @default.
- W2087753711 hasConceptScore W2087753711C2775864247 @default.
- W2087753711 hasConceptScore W2087753711C2776317618 @default.
- W2087753711 hasConceptScore W2087753711C2777529043 @default.
- W2087753711 hasConceptScore W2087753711C2777828372 @default.
- W2087753711 hasConceptScore W2087753711C2778897192 @default.
- W2087753711 hasConceptScore W2087753711C2780712732 @default.
- W2087753711 hasConceptScore W2087753711C2908747647 @default.
- W2087753711 hasConceptScore W2087753711C37000724 @default.
- W2087753711 hasConceptScore W2087753711C558461103 @default.
- W2087753711 hasConceptScore W2087753711C71924100 @default.
- W2087753711 hasIssue "2-3" @default.
- W2087753711 hasLocation W20877537111 @default.
- W2087753711 hasLocation W20877537112 @default.
- W2087753711 hasOpenAccess W2087753711 @default.
- W2087753711 hasPrimaryLocation W20877537111 @default.
- W2087753711 hasRelatedWork W10734341 @default.
- W2087753711 hasRelatedWork W2007139949 @default.
- W2087753711 hasRelatedWork W2007796416 @default.