FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087756493> ?p ?o ?g. }

• W2087756493 endingPage "1081" @default.
• W2087756493 startingPage "1075" @default.
• W2087756493 abstract "Aims: To study the growth inhibitory properties of a series of phytosphingosine (PHS) and phytoceramide (PHC) analogues. Methods and Results: A panel of two yeast (Candida albicans and Saccharomyces cerevisiae) and six moulds (Aspergillus repens, Aspergillus niger, Penicillium chrysogenum, Cladosporium cladosporioides, Arthroderma uncinatum and Penicillium funiculosum) has been used in this study. A series of new PHS and PHC analogues differing at the sphingoid backbone and the functional group at C1 position were synthesized. Conclusions: Among PHS analogues, 1-azido derivative 1c, bearing the natural d-ribo stereochemistry, showed a promising growth inhibitory profile. Among PHC analogues, compound 12, with a bulky N-pivaloyl group and a Z double bond at C3 position of the sphingoid chain, was the most active growth inhibitor. Minimal inhibitory concentration values were in the range of 23–48 μmol l−1 for 1c and 44–87 μmol l−1 for 12. Significance and Impact of the Study: Only scattered data on the antifungal activity of phytosphingolipids have been reported in the literature. This is the first time that a series of analogues of this kind are tested and compared to discern their structural requirements for antifungal activity." @default.
• W2087756493 created "2016-06-24" @default.
• W2087756493 creator A5035394841 @default.
• W2087756493 creator A5038880665 @default.
• W2087756493 creator A5055633226 @default.
• W2087756493 creator A5071507961 @default.
• W2087756493 creator A5080746703 @default.
• W2087756493 date "2008-04-01" @default.
• W2087756493 modified "2023-09-23" @default.
• W2087756493 title "Fungal growth inhibitory properties of new phytosphingolipid analogues" @default.
• W2087756493 cites W1581699504 @default.
• W2087756493 cites W1680920356 @default.
• W2087756493 cites W1974618932 @default.
• W2087756493 cites W1979793660 @default.
• W2087756493 cites W1984164793 @default.
• W2087756493 cites W1988477597 @default.
• W2087756493 cites W1991598314 @default.
• W2087756493 cites W2001621825 @default.
• W2087756493 cites W2003374787 @default.
• W2087756493 cites W2025518804 @default.
• W2087756493 cites W2038274403 @default.
• W2087756493 cites W2040810020 @default.
• W2087756493 cites W2044666681 @default.
• W2087756493 cites W2046407001 @default.
• W2087756493 cites W2053505134 @default.
• W2087756493 cites W2068540935 @default.
• W2087756493 cites W2086340560 @default.
• W2087756493 cites W2087711181 @default.
• W2087756493 cites W2092162378 @default.
• W2087756493 cites W2098211469 @default.
• W2087756493 cites W2099420541 @default.
• W2087756493 cites W2111155291 @default.
• W2087756493 cites W2154818679 @default.
• W2087756493 cites W2162062509 @default.
• W2087756493 cites W2164364672 @default.
• W2087756493 cites W2165348233 @default.
• W2087756493 cites W2950887232 @default.
• W2087756493 doi "https://doi.org/10.1111/j.1365-2672.2007.03635.x" @default.
• W2087756493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18005346" @default.
• W2087756493 hasPublicationYear "2008" @default.
• W2087756493 type Work @default.
• W2087756493 sameAs 2087756493 @default.
• W2087756493 citedByCount "7" @default.
• W2087756493 countsByYear W20877564932014 @default.
• W2087756493 countsByYear W20877564932015 @default.
• W2087756493 countsByYear W20877564932020 @default.
• W2087756493 countsByYear W20877564932021 @default.
• W2087756493 crossrefType "journal-article" @default.
• W2087756493 hasAuthorship W2087756493A5035394841 @default.
• W2087756493 hasAuthorship W2087756493A5038880665 @default.
• W2087756493 hasAuthorship W2087756493A5055633226 @default.
• W2087756493 hasAuthorship W2087756493A5071507961 @default.
• W2087756493 hasAuthorship W2087756493A5080746703 @default.
• W2087756493 hasBestOaLocation W20877564932 @default.
• W2087756493 hasConcept C185592680 @default.
• W2087756493 hasConcept C2775960407 @default.
• W2087756493 hasConcept C2777270571 @default.
• W2087756493 hasConcept C2777484150 @default.
• W2087756493 hasConcept C2777576037 @default.
• W2087756493 hasConcept C2779222958 @default.
• W2087756493 hasConcept C2779999543 @default.
• W2087756493 hasConcept C2780917455 @default.
• W2087756493 hasConcept C55493867 @default.
• W2087756493 hasConcept C59822182 @default.
• W2087756493 hasConcept C71240020 @default.
• W2087756493 hasConcept C86803240 @default.
• W2087756493 hasConcept C89423630 @default.
• W2087756493 hasConceptScore W2087756493C185592680 @default.
• W2087756493 hasConceptScore W2087756493C2775960407 @default.
• W2087756493 hasConceptScore W2087756493C2777270571 @default.
• W2087756493 hasConceptScore W2087756493C2777484150 @default.
• W2087756493 hasConceptScore W2087756493C2777576037 @default.
• W2087756493 hasConceptScore W2087756493C2779222958 @default.
• W2087756493 hasConceptScore W2087756493C2779999543 @default.
• W2087756493 hasConceptScore W2087756493C2780917455 @default.
• W2087756493 hasConceptScore W2087756493C55493867 @default.
• W2087756493 hasConceptScore W2087756493C59822182 @default.
• W2087756493 hasConceptScore W2087756493C71240020 @default.
• W2087756493 hasConceptScore W2087756493C86803240 @default.
• W2087756493 hasConceptScore W2087756493C89423630 @default.
• W2087756493 hasIssue "4" @default.
• W2087756493 hasLocation W20877564931 @default.
• W2087756493 hasLocation W20877564932 @default.
• W2087756493 hasLocation W20877564933 @default.
• W2087756493 hasOpenAccess W2087756493 @default.
• W2087756493 hasPrimaryLocation W20877564931 @default.
• W2087756493 hasRelatedWork W1596521974 @default.
• W2087756493 hasRelatedWork W201118680 @default.
• W2087756493 hasRelatedWork W2062385823 @default.
• W2087756493 hasRelatedWork W2081079750 @default.
• W2087756493 hasRelatedWork W2293161174 @default.
• W2087756493 hasRelatedWork W2390945406 @default.
• W2087756493 hasRelatedWork W2409637265 @default.
• W2087756493 hasRelatedWork W2417032728 @default.
• W2087756493 hasRelatedWork W2790371276 @default.
• W2087756493 hasRelatedWork W3044780684 @default.
• W2087756493 hasVolume "104" @default.
• W2087756493 isParatext "false" @default.

• next