Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087758093> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2087758093 abstract "Abstract A method for the simultaneous determination of phenobarbital (PB), phenytoin (PT), carbamazepine (CBZ), carbamazepine-10,11- epoxide (EPO), and N-desmethyl methsuximide (DM) in very small amounts of human brain (20–100 mg) is described. The weighed tissue is homogenized with a neutral buffer solution containing the internal standard (IS) 5-ethyl-5-(p-tolyl)-barbituric acid (ETB). The antiepileptic drugs (AEDs) are extracted with acetone from the homogenate. After centrifugation the drug solution is transferred onto an Extrelut(R)-III tube (filled with kieselguhr) and an acidic buffer is added. The AEDs are extracted from the matrix by di-chloro methane/propanol-(2) (97:3). The solvents are evaporated off and the residues taken up in methanol/water. The concentrated drug solution is injected into a microbore column which is filled with ODS silica gel (5 um). The mobile phase for the gradient elution is a mixture of a 0.05 M ammonium di-hydrogen phosphate buffer (pH 4.4) and acetonitrile. The colum..." @default.
- W2087758093 created "2016-06-24" @default.
- W2087758093 creator A5048260992 @default.
- W2087758093 creator A5057748694 @default.
- W2087758093 date "1987-06-01" @default.
- W2087758093 modified "2023-09-25" @default.
- W2087758093 title "Sensitive Analysis of Antiepileptic Drugs in Very Small Portions of Human Brain by Microbore HPLC" @default.
- W2087758093 cites W1904904806 @default.
- W2087758093 cites W1964837978 @default.
- W2087758093 cites W1976841519 @default.
- W2087758093 cites W199344695 @default.
- W2087758093 cites W2005840484 @default.
- W2087758093 cites W2008718878 @default.
- W2087758093 cites W2021564673 @default.
- W2087758093 cites W2040837665 @default.
- W2087758093 cites W2052035180 @default.
- W2087758093 cites W2058986127 @default.
- W2087758093 cites W2072763329 @default.
- W2087758093 cites W2086245168 @default.
- W2087758093 cites W2161475611 @default.
- W2087758093 cites W2161841233 @default.
- W2087758093 cites W4300776223 @default.
- W2087758093 doi "https://doi.org/10.1080/01483918708066802" @default.
- W2087758093 hasPublicationYear "1987" @default.
- W2087758093 type Work @default.
- W2087758093 sameAs 2087758093 @default.
- W2087758093 citedByCount "15" @default.
- W2087758093 crossrefType "journal-article" @default.
- W2087758093 hasAuthorship W2087758093A5048260992 @default.
- W2087758093 hasAuthorship W2087758093A5057748694 @default.
- W2087758093 hasConcept C169760540 @default.
- W2087758093 hasConcept C178790620 @default.
- W2087758093 hasConcept C185592680 @default.
- W2087758093 hasConcept C2777463227 @default.
- W2087758093 hasConcept C2778186239 @default.
- W2087758093 hasConcept C2778793413 @default.
- W2087758093 hasConcept C2779253243 @default.
- W2087758093 hasConcept C2779607525 @default.
- W2087758093 hasConcept C2781213060 @default.
- W2087758093 hasConcept C43617362 @default.
- W2087758093 hasConcept C71924100 @default.
- W2087758093 hasConcept C73826308 @default.
- W2087758093 hasConcept C86803240 @default.
- W2087758093 hasConcept C98274493 @default.
- W2087758093 hasConceptScore W2087758093C169760540 @default.
- W2087758093 hasConceptScore W2087758093C178790620 @default.
- W2087758093 hasConceptScore W2087758093C185592680 @default.
- W2087758093 hasConceptScore W2087758093C2777463227 @default.
- W2087758093 hasConceptScore W2087758093C2778186239 @default.
- W2087758093 hasConceptScore W2087758093C2778793413 @default.
- W2087758093 hasConceptScore W2087758093C2779253243 @default.
- W2087758093 hasConceptScore W2087758093C2779607525 @default.
- W2087758093 hasConceptScore W2087758093C2781213060 @default.
- W2087758093 hasConceptScore W2087758093C43617362 @default.
- W2087758093 hasConceptScore W2087758093C71924100 @default.
- W2087758093 hasConceptScore W2087758093C73826308 @default.
- W2087758093 hasConceptScore W2087758093C86803240 @default.
- W2087758093 hasConceptScore W2087758093C98274493 @default.
- W2087758093 hasLocation W20877580931 @default.
- W2087758093 hasOpenAccess W2087758093 @default.
- W2087758093 hasPrimaryLocation W20877580931 @default.
- W2087758093 hasRelatedWork W1512514318 @default.
- W2087758093 hasRelatedWork W1971079793 @default.
- W2087758093 hasRelatedWork W1979684447 @default.
- W2087758093 hasRelatedWork W1980979067 @default.
- W2087758093 hasRelatedWork W1989241766 @default.
- W2087758093 hasRelatedWork W1995265009 @default.
- W2087758093 hasRelatedWork W1996740108 @default.
- W2087758093 hasRelatedWork W1998315514 @default.
- W2087758093 hasRelatedWork W2004820285 @default.
- W2087758093 hasRelatedWork W2006593352 @default.
- W2087758093 hasRelatedWork W2010166209 @default.
- W2087758093 hasRelatedWork W2025949234 @default.
- W2087758093 hasRelatedWork W2040041388 @default.
- W2087758093 hasRelatedWork W2051264806 @default.
- W2087758093 hasRelatedWork W2056486509 @default.
- W2087758093 hasRelatedWork W2065266165 @default.
- W2087758093 hasRelatedWork W2072797708 @default.
- W2087758093 hasRelatedWork W2072991170 @default.
- W2087758093 hasRelatedWork W2089880002 @default.
- W2087758093 hasRelatedWork W2092291671 @default.
- W2087758093 isParatext "false" @default.
- W2087758093 isRetracted "false" @default.
- W2087758093 magId "2087758093" @default.
- W2087758093 workType "article" @default.