FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087765617> ?p ?o ?g. }

• W2087765617 endingPage "930" @default.
• W2087765617 startingPage "924" @default.
• W2087765617 abstract "Purified proteins such as antibodies are widely used as therapeutic agents in clinical medicine. However, clinical-grade proteins for therapeutic use require sophisticated technologies and are extremely expensive to produce. In vivo secretion of therapeutic proteins by genetically engineered human cells may advantageously replace injection of highly purified proteins. The use of gene transfer methods circumvents problems related to large-scale production and purification and offers additional benefits by achieving sustained concentrations of therapeutic protein with a syngenic glycosylation pattern that make the protein potentially less immunogenic. The feasibility of the in vivo production of therapeutic proteins by diverse cells/tissues has now been demonstrated using different techniques, such as ex vivo genetically modified cells and in vivo gene transfer mediated by viral vectors." @default.
• W2087765617 created "2016-06-24" @default.
• W2087765617 creator A5003276179 @default.
• W2087765617 creator A5031360602 @default.
• W2087765617 creator A5042598309 @default.
• W2087765617 date "2011-12-01" @default.
• W2087765617 modified "2023-10-17" @default.
• W2087765617 title "Engineering human cells for in vivo secretion of antibody and non-antibody therapeutic proteins" @default.
• W2087765617 cites W1965744027 @default.
• W2087765617 cites W1966422780 @default.
• W2087765617 cites W1967300094 @default.
• W2087765617 cites W1967334867 @default.
• W2087765617 cites W1969913120 @default.
• W2087765617 cites W1971482449 @default.
• W2087765617 cites W1976340920 @default.
• W2087765617 cites W1976578041 @default.
• W2087765617 cites W1977255778 @default.
• W2087765617 cites W1982994178 @default.
• W2087765617 cites W1983227853 @default.
• W2087765617 cites W1983775522 @default.
• W2087765617 cites W1985040895 @default.
• W2087765617 cites W1988508505 @default.
• W2087765617 cites W1991723371 @default.
• W2087765617 cites W1993524800 @default.
• W2087765617 cites W1994788053 @default.
• W2087765617 cites W2002095432 @default.
• W2087765617 cites W2002522963 @default.
• W2087765617 cites W2004222354 @default.
• W2087765617 cites W2007566237 @default.
• W2087765617 cites W2012468528 @default.
• W2087765617 cites W2012893428 @default.
• W2087765617 cites W2013001445 @default.
• W2087765617 cites W2014199384 @default.
• W2087765617 cites W2017158760 @default.
• W2087765617 cites W2017304478 @default.
• W2087765617 cites W2021401577 @default.
• W2087765617 cites W2029617091 @default.
• W2087765617 cites W2032109946 @default.
• W2087765617 cites W2032282401 @default.
• W2087765617 cites W2032410497 @default.
• W2087765617 cites W2039060347 @default.
• W2087765617 cites W2041360667 @default.
• W2087765617 cites W2043047945 @default.
• W2087765617 cites W2044795911 @default.
• W2087765617 cites W2047909718 @default.
• W2087765617 cites W2049544264 @default.
• W2087765617 cites W2050132596 @default.
• W2087765617 cites W2053220081 @default.
• W2087765617 cites W2053602894 @default.
• W2087765617 cites W2056662191 @default.
• W2087765617 cites W2058438178 @default.
• W2087765617 cites W2059193290 @default.
• W2087765617 cites W2065633718 @default.
• W2087765617 cites W2065997104 @default.
• W2087765617 cites W2068546732 @default.
• W2087765617 cites W2068635250 @default.
• W2087765617 cites W2070254401 @default.
• W2087765617 cites W2078128226 @default.
• W2087765617 cites W2079562074 @default.
• W2087765617 cites W2080434484 @default.
• W2087765617 cites W2084936473 @default.
• W2087765617 cites W2087138901 @default.
• W2087765617 cites W2088464857 @default.
• W2087765617 cites W2090943603 @default.
• W2087765617 cites W2092443845 @default.
• W2087765617 cites W2092946257 @default.
• W2087765617 cites W2093402994 @default.
• W2087765617 cites W2094602424 @default.
• W2087765617 cites W2096676113 @default.
• W2087765617 cites W2098182642 @default.
• W2087765617 cites W2105709419 @default.
• W2087765617 cites W2113103868 @default.
• W2087765617 cites W2117825789 @default.
• W2087765617 cites W2137491282 @default.
• W2087765617 cites W2141753215 @default.
• W2087765617 cites W2141815918 @default.
• W2087765617 cites W2151238232 @default.
• W2087765617 cites W2152362793 @default.
• W2087765617 cites W2167454336 @default.
• W2087765617 cites W2169921558 @default.
• W2087765617 doi "https://doi.org/10.1016/j.copbio.2011.03.001" @default.
• W2087765617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21435857" @default.
• W2087765617 hasPublicationYear "2011" @default.
• W2087765617 type Work @default.
• W2087765617 sameAs 2087765617 @default.
• W2087765617 citedByCount "12" @default.
• W2087765617 countsByYear W20877656172012 @default.
• W2087765617 countsByYear W20877656172013 @default.
• W2087765617 countsByYear W20877656172014 @default.
• W2087765617 countsByYear W20877656172015 @default.
• W2087765617 countsByYear W20877656172017 @default.
• W2087765617 countsByYear W20877656172020 @default.
• W2087765617 countsByYear W20877656172021 @default.
• W2087765617 countsByYear W20877656172022 @default.
• W2087765617 crossrefType "journal-article" @default.
• W2087765617 hasAuthorship W2087765617A5003276179 @default.
• W2087765617 hasAuthorship W2087765617A5031360602 @default.
• W2087765617 hasAuthorship W2087765617A5042598309 @default.

• next