FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087766271> ?p ?o ?g. }

• W2087766271 endingPage "1982" @default.
• W2087766271 startingPage "1981" @default.
• W2087766271 abstract "To the Editor: Ciguatera outbreaks usually occur in the area between 35° north and 35° south latitude, mainly in the Caribbean, Indo-Pacific islands, and the Indian Ocean (1–5) (Figure). Occasionally, ciguatera poisoning has been reported outside disease endemic areas, such as the Bahamas, Canada, or Chile, but no case had been described in the West African region until now. European and Spanish cases have been rarely described and are mainly associated with seafood imported from disease-endemic regions (6).FigureWorldwide distribution of ciguatera. Gray indicates coral reef regions located between 35° north and 35° south latitudes; brown indicates disease-endemic areas of ciguatera; red circle indicates Canary Islands (latitude 28°06´ ...Ciguatera fish poisoning is a clinical syndrome caused by eating contaminated fish (1). The causative toxins of its clinical manifestations are ciguatoxins (7). These toxins are transmitted by dinoflagellates of the species Gambierdiscus toxicus, which lives adhered to damaged coral reefs in tropical seas (2). Herbivorous fish species accumulate toxins in their musculature, liver, and viscera after ingesting dinoflagellates. Larger marine carnivores eat contaminated fish and concentrate ciguatoxins (1,2).More than 425 species of fish are associated with ciguatera poisoning in humans. The most commonly implicated fish are barracuda, red snapper, grouper, amberjack, sea bass, surgeonfish, and moray (eel) (2,3). In January 2004, 2 fishermen captured a 26-kg amberjack (local name: Medregal Negro; scientific name: Seriola Rivoliana) while scuba diving along the coast of the Canary Islands, Spain. The fishermen filleted the fish and stored fillets in a household freezer. Within a few days, one of the fishermen and 4 family members consumed some fish, and neurologic and gastrointestinal symptoms developed within 30 minutes to 28 hours. The 5 family members sought treatment at the emergency room of Hospital de Fuerteventura and the Outpatient Clinic of Infectious Diseases and Tropical Medicine Service of Hospital Insular de Las Palmas.The 5 family members exhibited a combination of gastrointestinal (diarrhea [4 persons], nausea/vomiting [3 persons], metallic taste [1 person]), cardiologic (heart rhythm disturbances [2 persons]), systemic (fatigue [5 persons], itching [3 persons], dizziness (1 person]), and neurologic manifestations (myalgia [3 persons], peripheral paresthesia [3 persons], perioral numbness [2 persons], and reversal of hot and cold sensations [3 persons], which is pathognomonic of ciguatera poisoning). These clinical observations and laboratory data were collected from a prospective questionnaire filled in by physicians at the patients' first visits. No hematologic or biochemical abnormalities were detected in any patient. Based upon the symptomatic profiles, relationships of the patients, and their common dietary histories, ciguatera intoxication was diagnosed in all. None of the patients required hospitalization. The neurologic and gastrointestinal symptoms resolved over several weeks, but intermittent recurrence of some symptoms, at lower intensities, was noted for several months.A portion of the implicated fish was recovered from freezer storage at the fisherman's home. A solid-phase membrane immunobead assay with a monoclonal antibody directed against Pacific ciguatoxins and related polyether toxins was used to detect ciguatoxins or other antigenically related substances in fish tissues. Results were positive.A 150-g sample of the fish was delivered to the US Food and Drug Organization's Gulf Coast Seafood Laboratory, Dauphin Island, Alabama, USA, for sodium channel–specific in vitro assay (8) and liquid chromatography–mass spectrometry (LC/MS/MS) analysis. Assay results were positive and the ciguatoxin content of the fish sample was estimated to be 1.0 ppb (ng/g). Caribbean ciguatoxin (CCTX-1: MH+ m/z 1141.6) was confirmed by LC/MS/MS by using multiple reaction monitoring (9). The amount of ciguatoxin in the fish tissue estimated by in vitro assay was low, and close to the limit the LC/MS/MS method can detect. At least 2 additional toxins were detected in the fish sample by in vitro assay of liquid chromatography fractions. We cannot rule out the possibility that these toxins represent new ciguatoxinlike structures unique to the eastern Atlantic. Further studies are necessary to elucidate all toxins implicated in this outbreak.Classic symptoms of ciguatera developed in our patients after eating a fish they captured in the Canary Islands, which are not in the ciguatera-endemic zone (Figure). The preliminary results of this outbreak investigation suggest the presence of ciguatoxins or ciguatoxinlike structures in fish from temperate waters of the eastern Atlantic. Ciguatera poisoning is a matter of public health concern and residents of coastal West Africa and the regional island archipelagos could be a new community at risk for this seafood intoxication syndrome. We emphasize that ciguatera poisoning is a debilitating disease, and therapeutic intervention strategies are very limited (10)." @default.
• W2087766271 created "2016-06-24" @default.
• W2087766271 creator A5000993426 @default.
• W2087766271 creator A5009679262 @default.
• W2087766271 creator A5012958957 @default.
• W2087766271 creator A5022890687 @default.
• W2087766271 creator A5055595542 @default.
• W2087766271 creator A5067925682 @default.
• W2087766271 creator A5070510899 @default.
• W2087766271 creator A5073281731 @default.
• W2087766271 creator A5087639074 @default.
• W2087766271 date "2005-12-01" @default.
• W2087766271 modified "2023-10-18" @default.
• W2087766271 title "Ciguatera Fish Poisoning, Canary Islands" @default.
• W2087766271 cites W151889145 @default.
• W2087766271 cites W1913248895 @default.
• W2087766271 cites W2024893302 @default.
• W2087766271 cites W2043062593 @default.
• W2087766271 cites W2046839528 @default.
• W2087766271 cites W2054080192 @default.
• W2087766271 cites W2071344259 @default.
• W2087766271 cites W2078761191 @default.
• W2087766271 cites W2106043339 @default.
• W2087766271 cites W2423826805 @default.
• W2087766271 cites W4245721412 @default.
• W2087766271 doi "https://doi.org/10.3201/eid1112.050393" @default.
• W2087766271 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3367630" @default.
• W2087766271 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16485501" @default.
• W2087766271 hasPublicationYear "2005" @default.
• W2087766271 type Work @default.
• W2087766271 sameAs 2087766271 @default.
• W2087766271 citedByCount "117" @default.
• W2087766271 countsByYear W20877662712012 @default.
• W2087766271 countsByYear W20877662712013 @default.
• W2087766271 countsByYear W20877662712014 @default.
• W2087766271 countsByYear W20877662712015 @default.
• W2087766271 countsByYear W20877662712016 @default.
• W2087766271 countsByYear W20877662712017 @default.
• W2087766271 countsByYear W20877662712018 @default.
• W2087766271 countsByYear W20877662712019 @default.
• W2087766271 countsByYear W20877662712020 @default.
• W2087766271 countsByYear W20877662712021 @default.
• W2087766271 countsByYear W20877662712022 @default.
• W2087766271 countsByYear W20877662712023 @default.
• W2087766271 crossrefType "journal-article" @default.
• W2087766271 hasAuthorship W2087766271A5000993426 @default.
• W2087766271 hasAuthorship W2087766271A5009679262 @default.
• W2087766271 hasAuthorship W2087766271A5012958957 @default.
• W2087766271 hasAuthorship W2087766271A5022890687 @default.
• W2087766271 hasAuthorship W2087766271A5055595542 @default.
• W2087766271 hasAuthorship W2087766271A5067925682 @default.
• W2087766271 hasAuthorship W2087766271A5070510899 @default.
• W2087766271 hasAuthorship W2087766271A5073281731 @default.
• W2087766271 hasAuthorship W2087766271A5087639074 @default.
• W2087766271 hasBestOaLocation W20877662711 @default.
• W2087766271 hasConcept C145316831 @default.
• W2087766271 hasConcept C205649164 @default.
• W2087766271 hasConcept C2779937837 @default.
• W2087766271 hasConcept C2909208804 @default.
• W2087766271 hasConcept C505870484 @default.
• W2087766271 hasConcept C86803240 @default.
• W2087766271 hasConceptScore W2087766271C145316831 @default.
• W2087766271 hasConceptScore W2087766271C205649164 @default.
• W2087766271 hasConceptScore W2087766271C2779937837 @default.
• W2087766271 hasConceptScore W2087766271C2909208804 @default.
• W2087766271 hasConceptScore W2087766271C505870484 @default.
• W2087766271 hasConceptScore W2087766271C86803240 @default.
• W2087766271 hasIssue "12" @default.
• W2087766271 hasLocation W20877662711 @default.
• W2087766271 hasLocation W20877662712 @default.
• W2087766271 hasLocation W20877662713 @default.
• W2087766271 hasLocation W20877662714 @default.
• W2087766271 hasLocation W20877662715 @default.
• W2087766271 hasOpenAccess W2087766271 @default.
• W2087766271 hasPrimaryLocation W20877662711 @default.
• W2087766271 hasRelatedWork W1978102941 @default.
• W2087766271 hasRelatedWork W2001835821 @default.
• W2087766271 hasRelatedWork W2087397260 @default.
• W2087766271 hasRelatedWork W2129328301 @default.
• W2087766271 hasRelatedWork W2231454014 @default.
• W2087766271 hasRelatedWork W2335431845 @default.
• W2087766271 hasRelatedWork W2400035742 @default.
• W2087766271 hasRelatedWork W2912145609 @default.
• W2087766271 hasRelatedWork W3170356201 @default.
• W2087766271 hasRelatedWork W3199317718 @default.
• W2087766271 hasVolume "11" @default.
• W2087766271 isParatext "false" @default.
• W2087766271 isRetracted "false" @default.
• W2087766271 magId "2087766271" @default.
• W2087766271 workType "article" @default.