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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087790925> ?p ?o ?g. }

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• W2087790925 abstract "The synthesis and in vitro activities of a series of succinyl-nitrile-based inhibitors of Cathepsin S are described. Several members of this class show nanomolar inhibition of the target enzyme as well as cellular potency. The inhibitors displaying the greatest potency contain N-alkyl substituted piperidine and pyrrolidine rings spiro-fused to the alpha-carbon of the P1 residue." @default.
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• W2087790925 date "2007-05-01" @default.
• W2087790925 modified "2023-09-26" @default.
• W2087790925 title "Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors" @default.
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• W2087790925 doi "https://doi.org/10.1016/j.bmcl.2007.02.046" @default.
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