Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087804543> ?p ?o ?g. }
- W2087804543 endingPage "69" @default.
- W2087804543 startingPage "66" @default.
- W2087804543 abstract "In an investigation of the mechanism by which brain lesions result in delayed degeneration of neurons remote from the site of injury, neurons within the caudate nucleus of rats were destroyed by local injection of the excitotoxin ibotenic acid. Treatment resulted in the rapid degeneration of the striatonigral pathway including projections containing the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and delayed transneuronal death of neurons in the substantia nigra pars reticulata. The distribution of nigral cell loss corresponded to the loss of GABAergic terminals. Neuronal death was prevented by long-term intraventricular infusion of the GABA agonist muscimol. Delayed transneuronal degeneration may be produced by neuronal disinhibition consequent to loss of inhibitory inputs. Replacement of inhibitory transmitters by suitable drugs may prevent some forms of delayed neuronal death." @default.
- W2087804543 created "2016-06-24" @default.
- W2087804543 creator A5018014529 @default.
- W2087804543 creator A5085264920 @default.
- W2087804543 date "1987-01-02" @default.
- W2087804543 modified "2023-10-18" @default.
- W2087804543 title "Delayed Transneuronal Death of Substantia Nigra Neurons Prevented by γ-Aminobutyric Acid Agonist" @default.
- W2087804543 cites W1965948714 @default.
- W2087804543 cites W1975946135 @default.
- W2087804543 cites W1993405721 @default.
- W2087804543 cites W1993470377 @default.
- W2087804543 cites W1996455766 @default.
- W2087804543 cites W1998164097 @default.
- W2087804543 cites W2004896772 @default.
- W2087804543 cites W2005780620 @default.
- W2087804543 cites W2012129844 @default.
- W2087804543 cites W2014384509 @default.
- W2087804543 cites W2014486882 @default.
- W2087804543 cites W2031767378 @default.
- W2087804543 cites W2040806697 @default.
- W2087804543 cites W2066168019 @default.
- W2087804543 cites W2068832757 @default.
- W2087804543 cites W2073734156 @default.
- W2087804543 cites W2074870180 @default.
- W2087804543 cites W2083865005 @default.
- W2087804543 cites W2146613713 @default.
- W2087804543 cites W2162239416 @default.
- W2087804543 cites W2444475331 @default.
- W2087804543 cites W2410518510 @default.
- W2087804543 doi "https://doi.org/10.1126/science.3798095" @default.
- W2087804543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3798095" @default.
- W2087804543 hasPublicationYear "1987" @default.
- W2087804543 type Work @default.
- W2087804543 sameAs 2087804543 @default.
- W2087804543 citedByCount "216" @default.
- W2087804543 countsByYear W20878045432012 @default.
- W2087804543 countsByYear W20878045432013 @default.
- W2087804543 countsByYear W20878045432014 @default.
- W2087804543 countsByYear W20878045432015 @default.
- W2087804543 countsByYear W20878045432016 @default.
- W2087804543 countsByYear W20878045432017 @default.
- W2087804543 countsByYear W20878045432018 @default.
- W2087804543 countsByYear W20878045432019 @default.
- W2087804543 countsByYear W20878045432020 @default.
- W2087804543 crossrefType "journal-article" @default.
- W2087804543 hasAuthorship W2087804543A5018014529 @default.
- W2087804543 hasAuthorship W2087804543A5085264920 @default.
- W2087804543 hasConcept C137183658 @default.
- W2087804543 hasConcept C169760540 @default.
- W2087804543 hasConcept C170493617 @default.
- W2087804543 hasConcept C17077164 @default.
- W2087804543 hasConcept C185592680 @default.
- W2087804543 hasConcept C2776055257 @default.
- W2087804543 hasConcept C2776219046 @default.
- W2087804543 hasConcept C2776355744 @default.
- W2087804543 hasConcept C2776599063 @default.
- W2087804543 hasConcept C2777681179 @default.
- W2087804543 hasConcept C2777771985 @default.
- W2087804543 hasConcept C2778938600 @default.
- W2087804543 hasConcept C2779177108 @default.
- W2087804543 hasConcept C2779188335 @default.
- W2087804543 hasConcept C2780938664 @default.
- W2087804543 hasConcept C2781423529 @default.
- W2087804543 hasConcept C513476851 @default.
- W2087804543 hasConcept C529278444 @default.
- W2087804543 hasConcept C55493867 @default.
- W2087804543 hasConcept C86803240 @default.
- W2087804543 hasConceptScore W2087804543C137183658 @default.
- W2087804543 hasConceptScore W2087804543C169760540 @default.
- W2087804543 hasConceptScore W2087804543C170493617 @default.
- W2087804543 hasConceptScore W2087804543C17077164 @default.
- W2087804543 hasConceptScore W2087804543C185592680 @default.
- W2087804543 hasConceptScore W2087804543C2776055257 @default.
- W2087804543 hasConceptScore W2087804543C2776219046 @default.
- W2087804543 hasConceptScore W2087804543C2776355744 @default.
- W2087804543 hasConceptScore W2087804543C2776599063 @default.
- W2087804543 hasConceptScore W2087804543C2777681179 @default.
- W2087804543 hasConceptScore W2087804543C2777771985 @default.
- W2087804543 hasConceptScore W2087804543C2778938600 @default.
- W2087804543 hasConceptScore W2087804543C2779177108 @default.
- W2087804543 hasConceptScore W2087804543C2779188335 @default.
- W2087804543 hasConceptScore W2087804543C2780938664 @default.
- W2087804543 hasConceptScore W2087804543C2781423529 @default.
- W2087804543 hasConceptScore W2087804543C513476851 @default.
- W2087804543 hasConceptScore W2087804543C529278444 @default.
- W2087804543 hasConceptScore W2087804543C55493867 @default.
- W2087804543 hasConceptScore W2087804543C86803240 @default.
- W2087804543 hasIssue "4784" @default.
- W2087804543 hasLocation W20878045431 @default.
- W2087804543 hasLocation W20878045432 @default.
- W2087804543 hasOpenAccess W2087804543 @default.
- W2087804543 hasPrimaryLocation W20878045431 @default.
- W2087804543 hasRelatedWork W1972459904 @default.
- W2087804543 hasRelatedWork W2016138793 @default.
- W2087804543 hasRelatedWork W2045959301 @default.
- W2087804543 hasRelatedWork W2051558496 @default.
- W2087804543 hasRelatedWork W2073508040 @default.
- W2087804543 hasRelatedWork W2074112754 @default.