FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087845396> ?p ?o ?g. }

• W2087845396 endingPage "3060" @default.
• W2087845396 startingPage "3048" @default.
• W2087845396 abstract "Abstract Francisella tularensis is the causative agent of the zoonotic disease tularemia. Four subspecies of this pathogen, namely ssp. tularensis , mediaasiatica , holarctica , and novicida are spread throughout the northern hemisphere. Although there are marked variations in their virulence to mammals, the subspecies are difficult to identify as they are closely genetically related. We carried out the comparative proteome analysis of cellular extracts from isolates representing the highly virulent subspecies tularensis , and the less virulent subspecies mediaasiatica and holarctica in order to identify new diagnostic markers and putative factors of virulence. We identified 27 protein spots that were either specifically present or at significantly higher abundance in ssp. tularensis strains, 22 proteins in ssp. mediaasiatica strains, and 26 proteins in ssp. holarctica strains. Subspecies tularensis ‐specific proteins might represent putative virulence factors. Of 27 identified tularensis ‐specific spots 17 represented charge and mass variants of proteins occurring in other subspecies, 7 spots were found to be present at higher abundance, and 3 spots were specifically present in tularensis strains. Amongst them, PilP protein, as a component neccessary for the biogenesis of the type IV pilus, virulence and adhesion factor for many human pathogen, was identified. Furthermore, the identification of additional 27 proteins common for ssp. tularensis and mediaasiatica , and 19 proteins shared by ssp. mediaasiatica and holarctica documented apparent closer genetic similarity between ssp. tularensis and mediaasiatica ." @default.
• W2087845396 created "2016-06-24" @default.
• W2087845396 creator A5003313570 @default.
• W2087845396 creator A5007471774 @default.
• W2087845396 creator A5024734448 @default.
• W2087845396 creator A5050226871 @default.
• W2087845396 creator A5050285652 @default.
• W2087845396 creator A5066604555 @default.
• W2087845396 date "2004-10-01" @default.
• W2087845396 modified "2023-10-17" @default.
• W2087845396 title "Comparative proteome analysis of cellular proteins extracted from highly virulent <b><i>Francisella tularensis</i></b> ssp. <b><i>tularensis</i></b> and less virulent <b><i>F. tularensis</i></b> ssp. <b><i>holarctica</i></b> and <b><i>F. tularensis</i></b> ssp. <b><i>mediaasiatica</i></b>" @default.
• W2087845396 cites W1495025190 @default.
• W2087845396 cites W15684062 @default.
• W2087845396 cites W1581442411 @default.
• W2087845396 cites W1858195267 @default.
• W2087845396 cites W1919549708 @default.
• W2087845396 cites W1934921138 @default.
• W2087845396 cites W1947762817 @default.
• W2087845396 cites W1963415235 @default.
• W2087845396 cites W2010330824 @default.
• W2087845396 cites W2024120829 @default.
• W2087845396 cites W2031280089 @default.
• W2087845396 cites W2036077981 @default.
• W2087845396 cites W2040629531 @default.
• W2087845396 cites W2042259740 @default.
• W2087845396 cites W2086819236 @default.
• W2087845396 cites W2092007780 @default.
• W2087845396 cites W2093292138 @default.
• W2087845396 cites W2093548693 @default.
• W2087845396 cites W2096695579 @default.
• W2087845396 cites W2101166451 @default.
• W2087845396 cites W2101683535 @default.
• W2087845396 cites W2102071794 @default.
• W2087845396 cites W2105736821 @default.
• W2087845396 cites W2111968027 @default.
• W2087845396 cites W2113982808 @default.
• W2087845396 cites W2114583053 @default.
• W2087845396 cites W2127367385 @default.
• W2087845396 cites W2134564388 @default.
• W2087845396 cites W2135482759 @default.
• W2087845396 cites W2143629111 @default.
• W2087845396 cites W2145802889 @default.
• W2087845396 cites W2154652750 @default.
• W2087845396 cites W2169929748 @default.
• W2087845396 cites W4211067865 @default.
• W2087845396 doi "https://doi.org/10.1002/pmic.200400939" @default.
• W2087845396 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15378745" @default.
• W2087845396 hasPublicationYear "2004" @default.
• W2087845396 type Work @default.
• W2087845396 sameAs 2087845396 @default.
• W2087845396 citedByCount "50" @default.
• W2087845396 countsByYear W20878453962012 @default.
• W2087845396 countsByYear W20878453962013 @default.
• W2087845396 countsByYear W20878453962014 @default.
• W2087845396 countsByYear W20878453962015 @default.
• W2087845396 countsByYear W20878453962016 @default.
• W2087845396 countsByYear W20878453962017 @default.
• W2087845396 countsByYear W20878453962018 @default.
• W2087845396 countsByYear W20878453962020 @default.
• W2087845396 countsByYear W20878453962021 @default.
• W2087845396 crossrefType "journal-article" @default.
• W2087845396 hasAuthorship W2087845396A5003313570 @default.
• W2087845396 hasAuthorship W2087845396A5007471774 @default.
• W2087845396 hasAuthorship W2087845396A5024734448 @default.
• W2087845396 hasAuthorship W2087845396A5050226871 @default.
• W2087845396 hasAuthorship W2087845396A5050285652 @default.
• W2087845396 hasAuthorship W2087845396A5066604555 @default.
• W2087845396 hasConcept C104317684 @default.
• W2087845396 hasConcept C104397665 @default.
• W2087845396 hasConcept C151730666 @default.
• W2087845396 hasConcept C159047783 @default.
• W2087845396 hasConcept C17966761 @default.
• W2087845396 hasConcept C2775983634 @default.
• W2087845396 hasConcept C2776460866 @default.
• W2087845396 hasConcept C2780467176 @default.
• W2087845396 hasConcept C54355233 @default.
• W2087845396 hasConcept C60987743 @default.
• W2087845396 hasConcept C86803240 @default.
• W2087845396 hasConcept C89423630 @default.
• W2087845396 hasConceptScore W2087845396C104317684 @default.
• W2087845396 hasConceptScore W2087845396C104397665 @default.
• W2087845396 hasConceptScore W2087845396C151730666 @default.
• W2087845396 hasConceptScore W2087845396C159047783 @default.
• W2087845396 hasConceptScore W2087845396C17966761 @default.
• W2087845396 hasConceptScore W2087845396C2775983634 @default.
• W2087845396 hasConceptScore W2087845396C2776460866 @default.
• W2087845396 hasConceptScore W2087845396C2780467176 @default.
• W2087845396 hasConceptScore W2087845396C54355233 @default.
• W2087845396 hasConceptScore W2087845396C60987743 @default.
• W2087845396 hasConceptScore W2087845396C86803240 @default.
• W2087845396 hasConceptScore W2087845396C89423630 @default.
• W2087845396 hasIssue "10" @default.
• W2087845396 hasLocation W20878453961 @default.
• W2087845396 hasLocation W20878453962 @default.
• W2087845396 hasOpenAccess W2087845396 @default.
• W2087845396 hasPrimaryLocation W20878453961 @default.
• W2087845396 hasRelatedWork W180909500 @default.
• W2087845396 hasRelatedWork W1817228116 @default.

• next