FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087917879> ?p ?o ?g. }

• W2087917879 endingPage "1249.e7" @default.
• W2087917879 startingPage "1249.e1" @default.
• W2087917879 abstract "To study the effects of chronic ischemia on bladder purinoceptors. A close correlation between bladder ischemia and lower urinary tract symptoms has been reported. Purinoceptors contribute to important aspects of bladder function including sensation, neural signaling, and voiding contraction. Our goal was to examine purinoceptors expression in the ischemic overactive bladder.Moderate bladder ischemia was produced in rabbits by creating bilateral iliac artery atherosclerosis. After 8 weeks, bladder blood flow was measured, and cystometrograms were obtained. Bladder tissues from 8-week ischemic and age-matched control bladders were processed for the analysis of oxidative stress markers, P2X and P2Y purinoceptors expression, and transmission electron microscopy.Arterial atherosclerosis significantly decreased bladder blood flow. Markers of oxidative stress characterized by increased levels of advanced oxidation protein products and malondialdehyde were evident in the ischemic bladder tissues. Chronic ischemia and oxidative stress decreased the bladder capacity and increased spontaneous bladder contractions. Bladder pressure at micturition and intravesical pressure rise during contractions tended to be greater in the ischemic bladder but did not reach significance. Transmission electron microscopy showed smooth muscle cell and microvasculature structural damage and diffuse fibrosis. These changes in the ischemic bladder were associated with significant increases in purinoceptors P2X1, P2X2, P2X3, P2X4, P2X5, and P2X7 expression. The P2Y isoforms were not expressed in the rabbit bladder.Structural and functional changes in the chronically ischemic bladder were associated with upregulation of P2X receptor isoforms. Increased P2X expression may play a role in ischemia-induced bladder overactivity and noncompliance." @default.
• W2087917879 created "2016-06-24" @default.
• W2087917879 creator A5000604552 @default.
• W2087917879 creator A5014342573 @default.
• W2087917879 creator A5026984704 @default.
• W2087917879 creator A5042826265 @default.
• W2087917879 creator A5060279706 @default.
• W2087917879 date "2014-11-01" @default.
• W2087917879 modified "2023-10-14" @default.
• W2087917879 title "Effects of Ischemia and Oxidative Stress on Bladder Purinoceptors Expression" @default.
• W2087917879 cites W1574413143 @default.
• W2087917879 cites W1623121663 @default.
• W2087917879 cites W1996739958 @default.
• W2087917879 cites W2030700436 @default.
• W2087917879 cites W2033931603 @default.
• W2087917879 cites W2052986896 @default.
• W2087917879 cites W2059285299 @default.
• W2087917879 cites W2060083375 @default.
• W2087917879 cites W2068922363 @default.
• W2087917879 cites W2070049861 @default.
• W2087917879 cites W2076661274 @default.
• W2087917879 cites W2087613565 @default.
• W2087917879 cites W2089363276 @default.
• W2087917879 cites W2095457664 @default.
• W2087917879 cites W2101859335 @default.
• W2087917879 cites W2118835581 @default.
• W2087917879 cites W2123770357 @default.
• W2087917879 cites W2134942830 @default.
• W2087917879 cites W2139978055 @default.
• W2087917879 cites W2140341287 @default.
• W2087917879 cites W2142609868 @default.
• W2087917879 cites W2144592553 @default.
• W2087917879 cites W2150371994 @default.
• W2087917879 cites W2159867066 @default.
• W2087917879 doi "https://doi.org/10.1016/j.urology.2014.07.023" @default.
• W2087917879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25219364" @default.
• W2087917879 hasPublicationYear "2014" @default.
• W2087917879 type Work @default.
• W2087917879 sameAs 2087917879 @default.
• W2087917879 citedByCount "24" @default.
• W2087917879 countsByYear W20879178792015 @default.
• W2087917879 countsByYear W20879178792016 @default.
• W2087917879 countsByYear W20879178792017 @default.
• W2087917879 countsByYear W20879178792018 @default.
• W2087917879 countsByYear W20879178792019 @default.
• W2087917879 countsByYear W20879178792020 @default.
• W2087917879 countsByYear W20879178792021 @default.
• W2087917879 countsByYear W20879178792022 @default.
• W2087917879 countsByYear W20879178792023 @default.
• W2087917879 crossrefType "journal-article" @default.
• W2087917879 hasAuthorship W2087917879A5000604552 @default.
• W2087917879 hasAuthorship W2087917879A5014342573 @default.
• W2087917879 hasAuthorship W2087917879A5026984704 @default.
• W2087917879 hasAuthorship W2087917879A5042826265 @default.
• W2087917879 hasAuthorship W2087917879A5060279706 @default.
• W2087917879 hasConcept C126322002 @default.
• W2087917879 hasConcept C126894567 @default.
• W2087917879 hasConcept C134018914 @default.
• W2087917879 hasConcept C142724271 @default.
• W2087917879 hasConcept C170493617 @default.
• W2087917879 hasConcept C204787440 @default.
• W2087917879 hasConcept C2776151105 @default.
• W2087917879 hasConcept C2778401633 @default.
• W2087917879 hasConcept C2778941218 @default.
• W2087917879 hasConcept C2779762690 @default.
• W2087917879 hasConcept C541997718 @default.
• W2087917879 hasConcept C57306754 @default.
• W2087917879 hasConcept C71924100 @default.
• W2087917879 hasConceptScore W2087917879C126322002 @default.
• W2087917879 hasConceptScore W2087917879C126894567 @default.
• W2087917879 hasConceptScore W2087917879C134018914 @default.
• W2087917879 hasConceptScore W2087917879C142724271 @default.
• W2087917879 hasConceptScore W2087917879C170493617 @default.
• W2087917879 hasConceptScore W2087917879C204787440 @default.
• W2087917879 hasConceptScore W2087917879C2776151105 @default.
• W2087917879 hasConceptScore W2087917879C2778401633 @default.
• W2087917879 hasConceptScore W2087917879C2778941218 @default.
• W2087917879 hasConceptScore W2087917879C2779762690 @default.
• W2087917879 hasConceptScore W2087917879C541997718 @default.
• W2087917879 hasConceptScore W2087917879C57306754 @default.
• W2087917879 hasConceptScore W2087917879C71924100 @default.
• W2087917879 hasFunder F4320306127 @default.
• W2087917879 hasIssue "5" @default.
• W2087917879 hasLocation W20879178791 @default.
• W2087917879 hasLocation W20879178792 @default.
• W2087917879 hasOpenAccess W2087917879 @default.
• W2087917879 hasPrimaryLocation W20879178791 @default.
• W2087917879 hasRelatedWork W1974959567 @default.
• W2087917879 hasRelatedWork W1982172676 @default.
• W2087917879 hasRelatedWork W2087917879 @default.
• W2087917879 hasRelatedWork W2118526472 @default.
• W2087917879 hasRelatedWork W2163502299 @default.
• W2087917879 hasRelatedWork W2896641258 @default.
• W2087917879 hasRelatedWork W2902664778 @default.
• W2087917879 hasRelatedWork W3014249079 @default.
• W2087917879 hasRelatedWork W4247432253 @default.
• W2087917879 hasRelatedWork W69721835 @default.
• W2087917879 hasVolume "84" @default.

• next