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• W2087923440 abstract "To examine associations of major complications after surgical treatment of slipped upper femoral epiphysis (SUFE) with condition- and treatment-related risk factors.This systematic review and meta-analysis of observational studies used an electronic literature search of Embase and Medline supplemented by a manual search of bibliographies. The studies enrolled children and adolescents with SUFE, defined stable and unstable disease, and reported at least 3 primary endpoints: avascular necrosis (AVN), chondrolysis, and reoperation. Random-effects meta-regression analysis was performed when possible.The weighted risk for AVN, derived from intercept-only meta-regression, was estimated as 5.3% (95% confidence interval [CI], 3.4%-7.2%). Patients with unstable slips had a 9.4-fold greater risk of developing AVN. Instability proved to be an independent predictor for AVN. The weighted risk of chondrolysis was 0.8% (95% CI, 0.2%-1.4%), associated with unstable slips and osteotomies. The risk of reoperation was estimated at 5.5% (95% CI, 1.7%-9.3%). Loss of fixation was the primary reason for reoperation.Current evidence indicates that unstable slips are at a significantly higher risk for AVN than stable slips, regardless of the attempted surgical approach. Little clinical information is available regarding chondrolysis and reoperation in relation to the stability of the physis." @default.
• W2087923440 created "2016-06-24" @default.
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• W2087923440 date "2010-10-01" @default.
• W2087923440 modified "2023-10-16" @default.
• W2087923440 title "Prognostic Significance of Stability in Slipped Upper Femoral Epiphysis: A Systematic Review and Meta-Analysis" @default.
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• W2087923440 doi "https://doi.org/10.1016/j.jpeds.2010.04.018" @default.
• W2087923440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20605166" @default.
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