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- W2087924755 abstract "Abstract New radiolabeled matrix metalloproteinase inhibitors (MMPIs) [11C]Me‐Halo‐CGS 27023A analogs have been synthesized for evaluation as potential novel positron emission tomography (PET) tumor imaging agents. Their lipophilicity coefficients (log P) were determined by C−18 reversed‐phase HPLC method. These logP values were compared, and the correlations between lipophilicity and biological activity of selected analogs were made. The results suggest the appropriate level of lipophilic character in this class of compounds as useful imaging agents appears to be in the range of 2.00–2.67." @default.
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- W2087924755 date "2005-03-01" @default.
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- W2087924755 title "Lipophilicity Coefficients of [<sup>11</sup>C]Me‐Halo‐CGS 27023A Analogs Determined by HPLC" @default.
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- W2087924755 doi "https://doi.org/10.1081/jlc-200051486" @default.
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