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- W2087929517 abstract "This study was designed to evaluate the effects of a high-protein (HP) diet on insulin resistance and body fat in catch-up growth (CUG) rats born small for gestational age (SGA).SGA rats were randomly divided into standard diet and HP diet groups. Perirenal fat weight and blood glucose, serum insulin and insulin-like growth factor-1 levels were measured at 4 and/or 8 weeks. Insulin resistance and β-cell function were evaluated by homeostatic model assessment for insulin resistance (HOMA-IR) and HOMA%.The values of HOMA-IR in both CUG-SGA groups were significantly higher than those in the appropriate for gestational age (AGA) group (p < 0.01), whereas they were significantly lower in the HP diet CUG-SGA group than in the standard diet CUG-SGA group at week 8 (p < 0.01). At week 8, perirenal fat weight and adipocyte diameters were higher in both CUG-SGA groups than in the AGA group (p < 0.05), but these values were significantly lower in the HP diet CUG-SGA group than in the standard diet CUG-SGA group (p < 0.05).The HP diet had positive effects on the prevention of insulin resistance, which may have been caused by the reduction of body fat." @default.
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- W2087929517 date "2012-01-01" @default.
- W2087929517 modified "2023-09-27" @default.
- W2087929517 title "Effects of a High-Protein Diet on Insulin Resistance and Body Fat in Catch-Up Growth Rats Born Small for Gestational Age" @default.
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- W2087929517 doi "https://doi.org/10.1159/000343149" @default.
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