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- W2087930031 abstract "In African trypanosomes, the expression of surface antigen genes is controlleed by several mechanisms which lead to their mutually exclusive activation, along with rapid evolution of their repertoires. This allows the parasite to escape the immune response of its mammalian host, and to develop waves of chronic infection. Analysis of these mechanisms has uncovered several interesting features for molecular geneticists, concerning DNA recombination, transcription and replication in telomeres. Although this potential for high variation precludes short-term vaccination, some possibilities for prophylaxy against human sleeping sickness can be envisaged." @default.
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- W2087930031 date "1986-01-01" @default.
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- W2087930031 title "Variability of antigen genes in African trypanosomes" @default.
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- W2087930031 doi "https://doi.org/10.1016/0168-9525(86)90164-2" @default.
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