Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087965685> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2087965685 endingPage "224" @default.
- W2087965685 startingPage "212" @default.
- W2087965685 abstract "TT virus (TTV) has been reported to occur in association with elevated alanine aminotransferase (ALT) levels in patients with posttransfusion hepatitis of unknown etiology. We examined whether the presence, change of DNA titer, or variation in sequence of this virus is associated with acute or chronic liver dysfunction in Japanese. We detected TTV by polymerase chain reaction (PCR) using primers generated from the conserved region of the TTV genome. Direct DNA sequencing of the original N22 region was used to characterize TTV isolates. We detected TTV DNA in 15 (25%) of 60 patients with liver dysfunction. Variants recovered from infected patients formed four genotypes/subtypes, corresponding to G1a, G1b, G2, and G4. Although TTV DNA titers in patients with G2 and G4 were lower than those with G1, TTV was consistently detected regardless of genotype/subtype. TTV infection continued for at least 1 year after normalization of ALT level in patients with acute liver dysfunction. Changes in DNA titer, substitutions of deduced amino acids, and variety of quasispecies of TTV were detected during the observation period, but no significant fluctuation in ALT level was found. We conclude that persistent infection, changes in DNA titer, and variation in sequence of this novel virus are not significantly related to hepatic disorders." @default.
- W2087965685 created "2016-06-24" @default.
- W2087965685 creator A5020924139 @default.
- W2087965685 creator A5030449856 @default.
- W2087965685 creator A5031054469 @default.
- W2087965685 creator A5044603246 @default.
- W2087965685 creator A5070281968 @default.
- W2087965685 date "2001-03-26" @default.
- W2087965685 modified "2023-09-27" @default.
- W2087965685 title "Changes of DNA titer and sequence variance of TT virus in hepatic disorders" @default.
- W2087965685 cites W1556991626 @default.
- W2087965685 cites W1963575432 @default.
- W2087965685 cites W1982921631 @default.
- W2087965685 cites W1983204059 @default.
- W2087965685 cites W1988911153 @default.
- W2087965685 cites W2018858310 @default.
- W2087965685 cites W2038264706 @default.
- W2087965685 cites W2044369474 @default.
- W2087965685 cites W2053512416 @default.
- W2087965685 cites W2067818192 @default.
- W2087965685 cites W2069607004 @default.
- W2087965685 cites W2069812190 @default.
- W2087965685 cites W2079599481 @default.
- W2087965685 cites W2089551619 @default.
- W2087965685 cites W2092027551 @default.
- W2087965685 cites W2093649367 @default.
- W2087965685 cites W2097902843 @default.
- W2087965685 cites W2121440740 @default.
- W2087965685 cites W2126256504 @default.
- W2087965685 cites W2132284948 @default.
- W2087965685 cites W2156404972 @default.
- W2087965685 cites W2255043511 @default.
- W2087965685 doi "https://doi.org/10.1016/s1386-6346(00)00106-6" @default.
- W2087965685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11251304" @default.
- W2087965685 hasPublicationYear "2001" @default.
- W2087965685 type Work @default.
- W2087965685 sameAs 2087965685 @default.
- W2087965685 citedByCount "5" @default.
- W2087965685 countsByYear W20879656852012 @default.
- W2087965685 countsByYear W20879656852013 @default.
- W2087965685 crossrefType "journal-article" @default.
- W2087965685 hasAuthorship W2087965685A5020924139 @default.
- W2087965685 hasAuthorship W2087965685A5030449856 @default.
- W2087965685 hasAuthorship W2087965685A5031054469 @default.
- W2087965685 hasAuthorship W2087965685A5044603246 @default.
- W2087965685 hasAuthorship W2087965685A5070281968 @default.
- W2087965685 hasConcept C104317684 @default.
- W2087965685 hasConcept C135763542 @default.
- W2087965685 hasConcept C141231307 @default.
- W2087965685 hasConcept C14500911 @default.
- W2087965685 hasConcept C159047783 @default.
- W2087965685 hasConcept C2522874641 @default.
- W2087965685 hasConcept C2776408679 @default.
- W2087965685 hasConcept C2779758228 @default.
- W2087965685 hasConcept C32611913 @default.
- W2087965685 hasConcept C49105822 @default.
- W2087965685 hasConcept C54355233 @default.
- W2087965685 hasConcept C86803240 @default.
- W2087965685 hasConceptScore W2087965685C104317684 @default.
- W2087965685 hasConceptScore W2087965685C135763542 @default.
- W2087965685 hasConceptScore W2087965685C141231307 @default.
- W2087965685 hasConceptScore W2087965685C14500911 @default.
- W2087965685 hasConceptScore W2087965685C159047783 @default.
- W2087965685 hasConceptScore W2087965685C2522874641 @default.
- W2087965685 hasConceptScore W2087965685C2776408679 @default.
- W2087965685 hasConceptScore W2087965685C2779758228 @default.
- W2087965685 hasConceptScore W2087965685C32611913 @default.
- W2087965685 hasConceptScore W2087965685C49105822 @default.
- W2087965685 hasConceptScore W2087965685C54355233 @default.
- W2087965685 hasConceptScore W2087965685C86803240 @default.
- W2087965685 hasIssue "3" @default.
- W2087965685 hasLocation W20879656851 @default.
- W2087965685 hasLocation W20879656852 @default.
- W2087965685 hasOpenAccess W2087965685 @default.
- W2087965685 hasPrimaryLocation W20879656851 @default.
- W2087965685 hasRelatedWork W1435627280 @default.
- W2087965685 hasRelatedWork W1968229989 @default.
- W2087965685 hasRelatedWork W2029008013 @default.
- W2087965685 hasRelatedWork W2047510921 @default.
- W2087965685 hasRelatedWork W2100701384 @default.
- W2087965685 hasRelatedWork W2126203350 @default.
- W2087965685 hasRelatedWork W2164225036 @default.
- W2087965685 hasRelatedWork W2189512835 @default.
- W2087965685 hasRelatedWork W4306659257 @default.
- W2087965685 hasRelatedWork W2189178250 @default.
- W2087965685 hasVolume "19" @default.
- W2087965685 isParatext "false" @default.
- W2087965685 isRetracted "false" @default.
- W2087965685 magId "2087965685" @default.
- W2087965685 workType "article" @default.