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• W2087966257 abstract "Lactating rats were exposed to 0, 5 or 25ppm cadmium as cadmium chloride in the drinking water. A battery of neurobehavioural tests was applied to the male offspring after weaning at 5 weeks until 4 months of age. The mean cadmium levels in exposed pup kidneys ranged from 0.006 to 0.030mg/kg wet weight at weaning, with the corresponding maternal kidney cadmium levels ranging from 4 to 13mg/kg wet weight. Significantly increased activity during the initial 20min of the spontaneous motor activity test was observed in the highest-dose group compared to the control group. The activity outcome was significantly positively correlated with cadmium levels in the pup kidneys. No cadmium-related changes in performance were observed in the Morris water maze, the E-shaped maze or the elevated plus-maze. The results indicate that neurobehavioural effects during development may be a more sensitive parameter for Cd toxicity than renal dysfunction." @default.
• W2087966257 created "2016-06-24" @default.
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• W2087966257 date "2004-05-01" @default.
• W2087966257 modified "2023-09-23" @default.
• W2087966257 title "Increased spontaneous motor activity in offspring after maternal cadmium exposure during lactation" @default.
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• W2087966257 doi "https://doi.org/10.1016/j.etap.2004.02.001" @default.
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