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- W2087995131 abstract "A cloned minisatellite, termed λMS29, that is unusual because it detects two variable loci in human DNA has been isolated. One locus, DNF21S1, located in the terminal region of the short arm of human chromosome 6, is also present in great apes. The second minisatellite locus, DNF21S2, is located interstitially on chromosome 16p11 and is absent both from non-human primates and from some humans. Physical mapping and sequencing show that the second locus has arisen recently in evolution by duplication of a large (> 15 kb) segment of chromosome 6 DNA containing a minisatellite and transposition onto chromosome 16 into a member of a novel low-copy-number repetitive DNA family. This unusual duplication/transposition event appears to represent the first example of a human DNA polymorphism arising through DNA-mediated, rather than RNA-mediated, transfer between autosomes." @default.
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- W2087995131 date "1990-06-01" @default.
- W2087995131 modified "2023-09-23" @default.
- W2087995131 title "A novel human DNA polymorphism resulting from transfer of DNA from chromosome 6 to chromosome 16" @default.
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- W2087995131 doi "https://doi.org/10.1016/0888-7543(90)90544-5" @default.
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