Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087996855> ?p ?o ?g. }
- W2087996855 endingPage "636" @default.
- W2087996855 startingPage "630" @default.
- W2087996855 abstract "Objectives: To review the contributions of cardiovascular disease to Alzheimer's disease and vascular dementia. Methods: Review of the literature. Results: Alzheimer's disease and vascular dementia both share significant risk attributable to cardiovascular risk factors. Hypertension and hypercholesterolemia at midlife are significant risk factors for both subsequent dementia. Diabetes and obesity are also risk factors for dementia. Stressful medical procedures, such as coronary artery bypass and graft operations also appear to contribute to the risk of Alzheimer's disease. Apolipoprotein E is the major risk factor for Alzheimer's disease. Apolipoprotein E does not appear to contribute to Alzheimer's disease by increasing serum cholesterol, but it might contribute to the disease through a mechanism involving both Aβ and an increase in neuronal vulnerability to stress. Discussion: The strong association of cardiovascular risk factors with Alzheimer's disease and vascular dementia suggest that these diseases share some biologic pathways in common. The contribution of cardiovascular disease to Alzheimer's disease and vascular dementia suggest that cardiovascular therapies might prove useful in treating or preventing dementia. Antihypertensive medications appear to be beneficial in preventing vascular dementia. Statins might be beneficial in preventing the progression of dementia in subjects with Alzheimer's disease." @default.
- W2087996855 created "2016-06-24" @default.
- W2087996855 creator A5071579004 @default.
- W2087996855 creator A5076516816 @default.
- W2087996855 date "2006-09-01" @default.
- W2087996855 modified "2023-10-18" @default.
- W2087996855 title "Interventions for heart disease and their effects on Alzheimer's disease" @default.
- W2087996855 cites W1503895697 @default.
- W2087996855 cites W1954313480 @default.
- W2087996855 cites W1965801493 @default.
- W2087996855 cites W1978841341 @default.
- W2087996855 cites W1980688966 @default.
- W2087996855 cites W1980906872 @default.
- W2087996855 cites W1982823300 @default.
- W2087996855 cites W1987762208 @default.
- W2087996855 cites W1991867131 @default.
- W2087996855 cites W1993668532 @default.
- W2087996855 cites W1997913988 @default.
- W2087996855 cites W1998664054 @default.
- W2087996855 cites W2003188394 @default.
- W2087996855 cites W2005481412 @default.
- W2087996855 cites W2006409771 @default.
- W2087996855 cites W2007898025 @default.
- W2087996855 cites W2009365915 @default.
- W2087996855 cites W2009869050 @default.
- W2087996855 cites W2011837326 @default.
- W2087996855 cites W2012215271 @default.
- W2087996855 cites W2016817047 @default.
- W2087996855 cites W2021181758 @default.
- W2087996855 cites W2026884356 @default.
- W2087996855 cites W2029205666 @default.
- W2087996855 cites W2034897558 @default.
- W2087996855 cites W2036362108 @default.
- W2087996855 cites W2039934896 @default.
- W2087996855 cites W2047613132 @default.
- W2087996855 cites W2050881912 @default.
- W2087996855 cites W2051993731 @default.
- W2087996855 cites W2057042201 @default.
- W2087996855 cites W2058138221 @default.
- W2087996855 cites W2070734601 @default.
- W2087996855 cites W2071345353 @default.
- W2087996855 cites W2072947218 @default.
- W2087996855 cites W2076517751 @default.
- W2087996855 cites W2079540265 @default.
- W2087996855 cites W2087141077 @default.
- W2087996855 cites W2098878950 @default.
- W2087996855 cites W2099284947 @default.
- W2087996855 cites W2099556509 @default.
- W2087996855 cites W2102320098 @default.
- W2087996855 cites W2104565625 @default.
- W2087996855 cites W2105489250 @default.
- W2087996855 cites W2107473715 @default.
- W2087996855 cites W2108326377 @default.
- W2087996855 cites W2109620996 @default.
- W2087996855 cites W2112039957 @default.
- W2087996855 cites W2122522567 @default.
- W2087996855 cites W2123457140 @default.
- W2087996855 cites W2124205593 @default.
- W2087996855 cites W2126615789 @default.
- W2087996855 cites W2131963133 @default.
- W2087996855 cites W2135631433 @default.
- W2087996855 cites W2145123193 @default.
- W2087996855 cites W2146405340 @default.
- W2087996855 cites W2149486086 @default.
- W2087996855 cites W2155210372 @default.
- W2087996855 cites W2158894504 @default.
- W2087996855 cites W2162294352 @default.
- W2087996855 cites W2162680540 @default.
- W2087996855 cites W2167720733 @default.
- W2087996855 cites W2169146425 @default.
- W2087996855 cites W2281384055 @default.
- W2087996855 cites W2325537322 @default.
- W2087996855 cites W23957462 @default.
- W2087996855 cites W4231517048 @default.
- W2087996855 cites W4233622592 @default.
- W2087996855 cites W4235732579 @default.
- W2087996855 cites W424467158 @default.
- W2087996855 cites W4293875546 @default.
- W2087996855 doi "https://doi.org/10.1179/016164106x130515" @default.
- W2087996855 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3913064" @default.
- W2087996855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16945215" @default.
- W2087996855 hasPublicationYear "2006" @default.
- W2087996855 type Work @default.
- W2087996855 sameAs 2087996855 @default.
- W2087996855 citedByCount "30" @default.
- W2087996855 countsByYear W20879968552012 @default.
- W2087996855 countsByYear W20879968552013 @default.
- W2087996855 countsByYear W20879968552015 @default.
- W2087996855 countsByYear W20879968552016 @default.
- W2087996855 countsByYear W20879968552017 @default.
- W2087996855 countsByYear W20879968552018 @default.
- W2087996855 countsByYear W20879968552020 @default.
- W2087996855 countsByYear W20879968552021 @default.
- W2087996855 crossrefType "journal-article" @default.
- W2087996855 hasAuthorship W2087996855A5071579004 @default.
- W2087996855 hasAuthorship W2087996855A5076516816 @default.
- W2087996855 hasBestOaLocation W20879968552 @default.
- W2087996855 hasConcept C126322002 @default.