FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088001552> ?p ?o ?g. }

• W2088001552 endingPage "396" @default.
• W2088001552 startingPage "393" @default.
• W2088001552 abstract "It is not known whether serum potassium levels affect blood pressure response to antihypertensive medication. The African American Study of Kidney Disease and Hypertension (AASK) Genomics Study (N=828) is a subset of the AASK trial that randomized 1094 African American men and women with hypertensive nephrosclerosis to ramipril, amlodipine or metoprolol. Participants were also randomized to a usual (102–107 mm Hg) or low (⩽92 mm Hg) mean arterial pressure (MAP) treatment goal. Time-to-event analyses were used to determine the relationship between serum potassium at randomization and time (days) to reach an MAP of 107 mm Hg. Mean baseline serum potassium was 4.22 mmol l−1 (s.d.±0.56 and range 2.8–6.0) and the median days to reach target MAP was 32 (interquartile range 8–95). The adjusted hazard ratio (HR) for each 1 mmol l−1 increase in serum potassium was 1.31 (95% confidence interval (CI): 1.08–1.59) in the usual MAP group, and 1.21 (95% CI: 1.02–1.44) in the low MAP group. Secondary findings suggested that women in the usual MAP group on amlodipine were more likely to reach target MAP compared with women randomized to ramipril (HR: 2.05, 95% CI: 1.30–3.21). Older subjects in the low MAP group (⩾55 years) were also more likely to reach target MAP on amlodipine compared with ramipril (HR: 1.57, 95% CI: 1.03–2.38). Serum potassium appears to be a significant predictor of time to blood pressure response, independent of drug class. The effect of serum potassium on blood pressure response to antihypertensive medications needs to be further studied in different patient populations." @default.
• W2088001552 created "2016-06-24" @default.
• W2088001552 creator A5005927388 @default.
• W2088001552 creator A5036087719 @default.
• W2088001552 creator A5048833376 @default.
• W2088001552 creator A5058631030 @default.
• W2088001552 creator A5089047049 @default.
• W2088001552 date "2012-11-15" @default.
• W2088001552 modified "2023-10-09" @default.
• W2088001552 title "Serum potassium predicts time to blood pressure response among African Americans with hypertensive nephrosclerosis" @default.
• W2088001552 cites W1976238931 @default.
• W2088001552 cites W1986747720 @default.
• W2088001552 cites W2003209602 @default.
• W2088001552 cites W2008516710 @default.
• W2088001552 cites W2021012510 @default.
• W2088001552 cites W2028336806 @default.
• W2088001552 cites W2043603709 @default.
• W2088001552 cites W2070801881 @default.
• W2088001552 cites W2075264236 @default.
• W2088001552 cites W2076118250 @default.
• W2088001552 cites W2076155335 @default.
• W2088001552 cites W2077910327 @default.
• W2088001552 cites W2086179586 @default.
• W2088001552 cites W2090860909 @default.
• W2088001552 cites W2120235169 @default.
• W2088001552 cites W2123107022 @default.
• W2088001552 cites W2134422033 @default.
• W2088001552 cites W2155765714 @default.
• W2088001552 cites W2160847021 @default.
• W2088001552 cites W2169859718 @default.
• W2088001552 cites W2170682979 @default.
• W2088001552 cites W2326215482 @default.
• W2088001552 cites W3213425522 @default.
• W2088001552 cites W4237383128 @default.
• W2088001552 cites W4256056939 @default.
• W2088001552 doi "https://doi.org/10.1038/jhh.2012.47" @default.
• W2088001552 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4537064" @default.
• W2088001552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23151750" @default.
• W2088001552 hasPublicationYear "2012" @default.
• W2088001552 type Work @default.
• W2088001552 sameAs 2088001552 @default.
• W2088001552 citedByCount "1" @default.
• W2088001552 countsByYear W20880015522015 @default.
• W2088001552 crossrefType "journal-article" @default.
• W2088001552 hasAuthorship W2088001552A5005927388 @default.
• W2088001552 hasAuthorship W2088001552A5036087719 @default.
• W2088001552 hasAuthorship W2088001552A5048833376 @default.
• W2088001552 hasAuthorship W2088001552A5058631030 @default.
• W2088001552 hasAuthorship W2088001552A5089047049 @default.
• W2088001552 hasBestOaLocation W20880015521 @default.
• W2088001552 hasConcept C119060515 @default.
• W2088001552 hasConcept C126322002 @default.
• W2088001552 hasConcept C126894567 @default.
• W2088001552 hasConcept C164705383 @default.
• W2088001552 hasConcept C168563851 @default.
• W2088001552 hasConcept C204243189 @default.
• W2088001552 hasConcept C207103383 @default.
• W2088001552 hasConcept C2779646130 @default.
• W2088001552 hasConcept C2779888176 @default.
• W2088001552 hasConcept C2780091579 @default.
• W2088001552 hasConcept C2911077047 @default.
• W2088001552 hasConcept C44249647 @default.
• W2088001552 hasConcept C71924100 @default.
• W2088001552 hasConcept C84393581 @default.
• W2088001552 hasConceptScore W2088001552C119060515 @default.
• W2088001552 hasConceptScore W2088001552C126322002 @default.
• W2088001552 hasConceptScore W2088001552C126894567 @default.
• W2088001552 hasConceptScore W2088001552C164705383 @default.
• W2088001552 hasConceptScore W2088001552C168563851 @default.
• W2088001552 hasConceptScore W2088001552C204243189 @default.
• W2088001552 hasConceptScore W2088001552C207103383 @default.
• W2088001552 hasConceptScore W2088001552C2779646130 @default.
• W2088001552 hasConceptScore W2088001552C2779888176 @default.
• W2088001552 hasConceptScore W2088001552C2780091579 @default.
• W2088001552 hasConceptScore W2088001552C2911077047 @default.
• W2088001552 hasConceptScore W2088001552C44249647 @default.
• W2088001552 hasConceptScore W2088001552C71924100 @default.
• W2088001552 hasConceptScore W2088001552C84393581 @default.
• W2088001552 hasIssue "6" @default.
• W2088001552 hasLocation W20880015521 @default.
• W2088001552 hasLocation W20880015522 @default.
• W2088001552 hasLocation W20880015523 @default.
• W2088001552 hasLocation W20880015524 @default.
• W2088001552 hasOpenAccess W2088001552 @default.
• W2088001552 hasPrimaryLocation W20880015521 @default.
• W2088001552 hasRelatedWork W2035945291 @default.
• W2088001552 hasRelatedWork W2111435044 @default.
• W2088001552 hasRelatedWork W2168557376 @default.
• W2088001552 hasRelatedWork W2349166799 @default.
• W2088001552 hasRelatedWork W2368088040 @default.
• W2088001552 hasRelatedWork W2375178265 @default.
• W2088001552 hasRelatedWork W2435813115 @default.
• W2088001552 hasRelatedWork W2767059609 @default.
• W2088001552 hasRelatedWork W3202571014 @default.
• W2088001552 hasRelatedWork W4383957414 @default.
• W2088001552 hasVolume "27" @default.
• W2088001552 isParatext "false" @default.
• W2088001552 isRetracted "false" @default.

• next