FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088049359> ?p ?o ?g. }

• W2088049359 endingPage "13484" @default.
• W2088049359 startingPage "13474" @default.
• W2088049359 abstract "We investigated analytically and numerically the interplay between two opposing forms of synaptic plasticity: positive-feedback, long-term potentiation/depression (LTP/LTD), and negative-feedback, homeostatic synaptic plasticity (HSP). A detailed model of a CA1 pyramidal neuron, with numerous HSP-modifiable dendritic synapses, demonstrates that HSP may have an important role in selecting which spatial patterns of LTP/LTD are to last. Several measures are developed for predicting the net residual potentiation/depression after HSP from the initial spatial pattern of LTP/LTD. Under a local dendritic HSP mechanism, sparse patterns of LTP/LTD, which we show, using information theoretical tools, to have a significant impact on the output of the postsynaptic neuron, will persist. In contrast, spatially clustered patterns with a smaller impact on the output will diminish. A global somatic HSP mechanism, conversely, will favor distally occurring LTP/LTDs over proximal ones. Despite the negative-feedback nature of HSP, under both local and global HSP, numerous synaptic potentiations/depressions can persist. These experimentally testable results imply that HSP could be significantly involved in shaping the spatial distribution of synaptic weights in the dendrites and not just normalizing it, as is currently believed." @default.
• W2088049359 created "2016-06-24" @default.
• W2088049359 creator A5025022011 @default.
• W2088049359 creator A5048156775 @default.
• W2088049359 date "2006-12-27" @default.
• W2088049359 modified "2023-10-17" @default.
• W2088049359 title "The Endurance and Selectivity of Spatial Patterns of Long-Term Potentiation/Depression in Dendrites under Homeostatic Synaptic Plasticity" @default.
• W2088049359 cites W1486852018 @default.
• W2088049359 cites W1489333352 @default.
• W2088049359 cites W1512624479 @default.
• W2088049359 cites W1514853588 @default.
• W2088049359 cites W1528942588 @default.
• W2088049359 cites W1598503391 @default.
• W2088049359 cites W1733248925 @default.
• W2088049359 cites W1855000541 @default.
• W2088049359 cites W1965265446 @default.
• W2088049359 cites W1969584830 @default.
• W2088049359 cites W1975117887 @default.
• W2088049359 cites W1982681520 @default.
• W2088049359 cites W1983553517 @default.
• W2088049359 cites W1991779336 @default.
• W2088049359 cites W1994119944 @default.
• W2088049359 cites W2001688314 @default.
• W2088049359 cites W2004803686 @default.
• W2088049359 cites W2005736512 @default.
• W2088049359 cites W2005793571 @default.
• W2088049359 cites W2009544901 @default.
• W2088049359 cites W2011432049 @default.
• W2088049359 cites W2015701831 @default.
• W2088049359 cites W2027699509 @default.
• W2088049359 cites W2031779883 @default.
• W2088049359 cites W2031898618 @default.
• W2088049359 cites W2037921808 @default.
• W2088049359 cites W2038365936 @default.
• W2088049359 cites W2039655932 @default.
• W2088049359 cites W2040003929 @default.
• W2088049359 cites W2046550620 @default.
• W2088049359 cites W2047103575 @default.
• W2088049359 cites W2053287773 @default.
• W2088049359 cites W2053909281 @default.
• W2088049359 cites W2057426891 @default.
• W2088049359 cites W2065546903 @default.
• W2088049359 cites W2066781880 @default.
• W2088049359 cites W2067187446 @default.
• W2088049359 cites W2076837924 @default.
• W2088049359 cites W2079481027 @default.
• W2088049359 cites W2084518163 @default.
• W2088049359 cites W2089413793 @default.
• W2088049359 cites W2095202445 @default.
• W2088049359 cites W2103594871 @default.
• W2088049359 cites W2105949133 @default.
• W2088049359 cites W2106307904 @default.
• W2088049359 cites W2109161455 @default.
• W2088049359 cites W2136175743 @default.
• W2088049359 cites W2136425602 @default.
• W2088049359 cites W2143397316 @default.
• W2088049359 cites W2144925492 @default.
• W2088049359 cites W2146655366 @default.
• W2088049359 cites W2156259017 @default.
• W2088049359 cites W2156353006 @default.
• W2088049359 cites W2157238829 @default.
• W2088049359 cites W2160361560 @default.
• W2088049359 cites W2163758015 @default.
• W2088049359 cites W2168028420 @default.
• W2088049359 cites W2169541524 @default.
• W2088049359 doi "https://doi.org/10.1523/jneurosci.4333-06.2006" @default.
• W2088049359 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6674716" @default.
• W2088049359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17192430" @default.
• W2088049359 hasPublicationYear "2006" @default.
• W2088049359 type Work @default.
• W2088049359 sameAs 2088049359 @default.
• W2088049359 citedByCount "32" @default.
• W2088049359 countsByYear W20880493592012 @default.
• W2088049359 countsByYear W20880493592013 @default.
• W2088049359 countsByYear W20880493592014 @default.
• W2088049359 countsByYear W20880493592015 @default.
• W2088049359 countsByYear W20880493592016 @default.
• W2088049359 countsByYear W20880493592017 @default.
• W2088049359 countsByYear W20880493592022 @default.
• W2088049359 crossrefType "journal-article" @default.
• W2088049359 hasAuthorship W2088049359A5025022011 @default.
• W2088049359 hasAuthorship W2088049359A5048156775 @default.
• W2088049359 hasBestOaLocation W20880493591 @default.
• W2088049359 hasConcept C112592302 @default.
• W2088049359 hasConcept C117718741 @default.
• W2088049359 hasConcept C127445978 @default.
• W2088049359 hasConcept C169760540 @default.
• W2088049359 hasConcept C170493617 @default.
• W2088049359 hasConcept C17077164 @default.
• W2088049359 hasConcept C194973443 @default.
• W2088049359 hasConcept C197341189 @default.
• W2088049359 hasConcept C25274449 @default.
• W2088049359 hasConcept C26410512 @default.
• W2088049359 hasConcept C47611674 @default.
• W2088049359 hasConcept C55493867 @default.
• W2088049359 hasConcept C5687787 @default.
• W2088049359 hasConcept C86803240 @default.
• W2088049359 hasConcept C95293801 @default.

• next