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- W2088109286 abstract "In order to improve the guidance potential of a nerve entubulation bridging device, highly aligned textures were formed on the inner surface of semipermeable hollow fiber membranes (HFMs) during the wet phase inversion process. By precisely controlling the fabrication parameters, such as polymer solution flow rate, coagulant solution flow rate, and the air-gap distance, also called drop height, different-sized aligned grooves can be fabricated on the inner surface of HFMs. Preliminary studies using in vitro dorsal root ganglion (DRG) regeneration assay showed that both the alignment and outgrowth rate of regenerating axons increased significantly on HFMs with aligned textures compared to those on HFMs with a smooth inner surface. Studies in progress are evaluating axonal outgrowth and regeneration using in vivo sciatic-nerve and spinal-cord-injury models." @default.
- W2088109286 created "2016-06-24" @default.
- W2088109286 creator A5051851437 @default.
- W2088109286 creator A5054418515 @default.
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- W2088109286 date "2005-08-25" @default.
- W2088109286 modified "2023-10-13" @default.
- W2088109286 title "Fabrication of semipermeable hollow fiber membranes with highly aligned texture for nerve guidance" @default.
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- W2088109286 doi "https://doi.org/10.1002/jbm.a.30495" @default.
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