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- W2088115502 abstract "Reported mean values for urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) for both depressed patients and controls vary substantially between laboratories. The present study describes methodological sources of variance affecting urinary MHPG values. Although intra-assay variance is small (coefficient of variation (CV) = 4.6%), the interassay variance is high (CV = 14.3%) and suggests caution in the interpretation of small group differences. The gas chromatographic (GC) method in this laboratory produces values highly correlated (r = 0.98) with those obtained by a reference gas chromatographic-mass spectrometric (GC-MS) method. The absolute values obtained by GC are 20% higher than those by GC-MS--a problem that may be shared to a varying extent by all GC assays.methodological differences do contribute to some of the variation in reported values of urinary MHPG." @default.
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- W2088115502 date "1981-06-01" @default.
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- W2088115502 title "Methodological issues in the measurement of urinary MHPG" @default.
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- W2088115502 doi "https://doi.org/10.1016/0165-1781(81)90028-7" @default.
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