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- W2088127462 abstract "One-hundred and twenty-three polyethylene tube implants of 12 endodontic sealers were placed subcutaneously into rats. The implants were left in situ for periods of 14 and 90 days. The tissue response was analyzed histologically and by scanning X-ray microanalysis. The tissue responses differed markedly in the intensity, extent, and cellular characteristics. A slight long-term tissue response was noted for polymeric resin-based materials; zinc oxide-eugenol-based sealers gave a stronger reaction; and a chloroform-based and two paste-type materials caused the least favorable reactions. X-ray microanalysis of tissue sections revealed material components in the reactive capsule and in the peripheral connective tissue of most specimens investigated. Implants of the resin-based sealers, AH26 and Hydron, were surrounded by macrophages, phagocytosing heavy metal components (Bi, Ba) of the materials. Zinc oxide-eugenol- and chloroform-based materials appeared more frequently to fragment into particles of sizes too large for monocellular phagocytosis. One-hundred and twenty-three polyethylene tube implants of 12 endodontic sealers were placed subcutaneously into rats. The implants were left in situ for periods of 14 and 90 days. The tissue response was analyzed histologically and by scanning X-ray microanalysis. The tissue responses differed markedly in the intensity, extent, and cellular characteristics. A slight long-term tissue response was noted for polymeric resin-based materials; zinc oxide-eugenol-based sealers gave a stronger reaction; and a chloroform-based and two paste-type materials caused the least favorable reactions. X-ray microanalysis of tissue sections revealed material components in the reactive capsule and in the peripheral connective tissue of most specimens investigated. Implants of the resin-based sealers, AH26 and Hydron, were surrounded by macrophages, phagocytosing heavy metal components (Bi, Ba) of the materials. Zinc oxide-eugenol- and chloroform-based materials appeared more frequently to fragment into particles of sizes too large for monocellular phagocytosis." @default.
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- W2088127462 date "1988-01-01" @default.
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- W2088127462 title "Histopathology and X-ray microanalysis of the subcutaneous tissue response to endodontic sealers" @default.
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- W2088127462 doi "https://doi.org/10.1016/s0099-2399(88)80236-x" @default.
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