Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088128998> ?p ?o ?g. }
- W2088128998 endingPage "425" @default.
- W2088128998 startingPage "416" @default.
- W2088128998 abstract "Purpose of review The question of when to initiate antiretroviral treatment for children is perhaps the most critical unanswered question in pediatric HIV therapeutics. With large numbers of children throughout the world acquiring HIV infection and with improved global access to HIV treatment it is particularly timely to consider the optimal time to initiate antiretroviral therapy in infants, children and adolescents. Recent findings Early treatment can result in suppression of HIV viremia, immune preservation and prevention of disease progression. This must be balanced by the challenges of maintaining adherence to multidrug regimens, the risks of selecting drug-resistant virus, and long and short-term toxicities of medications. Summary This review provides a framework within which to consider when to initiate children on antiretroviral treatment. A child's age and developmental status, where they live, and the goals and expectations for treatment provide a context for balancing the risks of disease progression with the risks of drug-related toxicities and viral resistance." @default.
- W2088128998 created "2016-06-24" @default.
- W2088128998 creator A5058881734 @default.
- W2088128998 date "2007-09-01" @default.
- W2088128998 modified "2023-09-24" @default.
- W2088128998 title "The unanswered question: when to initiate antiretroviral therapy in children with HIV infection" @default.
- W2088128998 cites W1497170016 @default.
- W2088128998 cites W1516480248 @default.
- W2088128998 cites W1522239606 @default.
- W2088128998 cites W1549637102 @default.
- W2088128998 cites W1596626870 @default.
- W2088128998 cites W1966624986 @default.
- W2088128998 cites W1971771720 @default.
- W2088128998 cites W1971927429 @default.
- W2088128998 cites W1979564083 @default.
- W2088128998 cites W1981937271 @default.
- W2088128998 cites W1994477876 @default.
- W2088128998 cites W1995519304 @default.
- W2088128998 cites W1996828265 @default.
- W2088128998 cites W2005617325 @default.
- W2088128998 cites W2005732333 @default.
- W2088128998 cites W2006291559 @default.
- W2088128998 cites W2006973096 @default.
- W2088128998 cites W2011656694 @default.
- W2088128998 cites W2012313372 @default.
- W2088128998 cites W2012377587 @default.
- W2088128998 cites W2015491389 @default.
- W2088128998 cites W2020292793 @default.
- W2088128998 cites W2024056053 @default.
- W2088128998 cites W2024236584 @default.
- W2088128998 cites W2028099639 @default.
- W2088128998 cites W2035391525 @default.
- W2088128998 cites W2036250213 @default.
- W2088128998 cites W2036594368 @default.
- W2088128998 cites W2039596291 @default.
- W2088128998 cites W2043122232 @default.
- W2088128998 cites W2043396849 @default.
- W2088128998 cites W2051272543 @default.
- W2088128998 cites W2054980981 @default.
- W2088128998 cites W2058010369 @default.
- W2088128998 cites W2058472104 @default.
- W2088128998 cites W2059873581 @default.
- W2088128998 cites W2060513447 @default.
- W2088128998 cites W2061577259 @default.
- W2088128998 cites W2067051705 @default.
- W2088128998 cites W2068884761 @default.
- W2088128998 cites W2075230143 @default.
- W2088128998 cites W2083035734 @default.
- W2088128998 cites W2084192059 @default.
- W2088128998 cites W2085628809 @default.
- W2088128998 cites W2088275158 @default.
- W2088128998 cites W2088874312 @default.
- W2088128998 cites W2089032846 @default.
- W2088128998 cites W2090740440 @default.
- W2088128998 cites W2093979189 @default.
- W2088128998 cites W2102326515 @default.
- W2088128998 cites W2118749241 @default.
- W2088128998 cites W2126952925 @default.
- W2088128998 cites W2127300645 @default.
- W2088128998 cites W2131639307 @default.
- W2088128998 cites W2132271398 @default.
- W2088128998 cites W2132845988 @default.
- W2088128998 cites W2133166320 @default.
- W2088128998 cites W2139402719 @default.
- W2088128998 cites W2139984845 @default.
- W2088128998 cites W2142356600 @default.
- W2088128998 cites W2144275513 @default.
- W2088128998 cites W2148521133 @default.
- W2088128998 cites W2148684707 @default.
- W2088128998 cites W2150410879 @default.
- W2088128998 cites W2151922892 @default.
- W2088128998 cites W2153494870 @default.
- W2088128998 cites W2155753953 @default.
- W2088128998 cites W2162609634 @default.
- W2088128998 cites W2162881343 @default.
- W2088128998 cites W2162945621 @default.
- W2088128998 cites W2163955993 @default.
- W2088128998 cites W2164216283 @default.
- W2088128998 cites W2164241626 @default.
- W2088128998 cites W2166738638 @default.
- W2088128998 cites W2312499014 @default.
- W2088128998 cites W2313922401 @default.
- W2088128998 cites W2490541401 @default.
- W2088128998 cites W4232900179 @default.
- W2088128998 cites W83931366 @default.
- W2088128998 doi "https://doi.org/10.1097/coh.0b013e3282cef1ee" @default.
- W2088128998 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19372921" @default.
- W2088128998 hasPublicationYear "2007" @default.
- W2088128998 type Work @default.
- W2088128998 sameAs 2088128998 @default.
- W2088128998 citedByCount "3" @default.
- W2088128998 crossrefType "journal-article" @default.
- W2088128998 hasAuthorship W2088128998A5058881734 @default.
- W2088128998 hasConcept C114851261 @default.
- W2088128998 hasConcept C126322002 @default.
- W2088128998 hasConcept C142462285 @default.
- W2088128998 hasConcept C151730666 @default.
- W2088128998 hasConcept C177713679 @default.