FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088130488> ?p ?o ?g. }

• W2088130488 endingPage "57" @default.
• W2088130488 startingPage "53" @default.
• W2088130488 abstract "Earlier results highlighted hyperferritinemia during type-1 Gaucher disease (GD), but its potential mechanisms and long-term progression remained unexamined. We analyzed the clinical, biological and iron characteristics of type-1 GD patients, before and after starting enzyme-replacement therapy (ERT). Iron parameters under ERT were subjected to linear-regression analyses. Serum ferritin (median 739 [46–2371] μg/L) was determined for 54 patients (21 (39%) males; median age 32 [range 12–73] years) before ERT; it exceeded 300 μg/L in 47 (87%), while the other iron parameters always remained normal: transferrin saturation coefficient (26 [16–42]), serum iron at 13 [6–22] mmol/L and transferrin at 2.4 [2,3] g/L. Four patients had mild elevation of liver transaminases, with C-reactive protein > 20 mg/l in two. The absence of hemolysis was accompanied by a median bilirubin of 9 μmol/L and lactate dehydrogenase at 250 IU/L; diabetes and lipid anomalies were not observed. Clinical, biological and iron parameters at GD diagnosis were comparable for the 12 and 42 patients with ferritinemia ≤ 400 and > 400 μg/L, respectively. Ferritinemia was measured at least once for 46 patients after ERT onset (median treatment duration 90 [3–204] months). At study closure, median serum ferritin was 187.5 [11–1560] μg/L, exceeding 300 μg/L in 15 (33%) patients, while the other iron parameters were normal. Among the latter, only the mean ± SD ferritinemia slope decreased significantly under ERT (− 1.9 ± 0.3%/month; p < 0.001). Hyperferritinemia is a specific GD characteristic and serum ferritin monitoring could be informative during follow-up." @default.
• W2088130488 created "2016-06-24" @default.
• W2088130488 creator A5032207811 @default.
• W2088130488 creator A5032873950 @default.
• W2088130488 creator A5041077575 @default.
• W2088130488 creator A5042547987 @default.
• W2088130488 creator A5055335263 @default.
• W2088130488 creator A5069537100 @default.
• W2088130488 creator A5074956599 @default.
• W2088130488 creator A5087386909 @default.
• W2088130488 date "2012-06-01" @default.
• W2088130488 modified "2023-10-12" @default.
• W2088130488 title "Ferritinemia during type 1 Gaucher disease: Mechanisms and progression under treatment" @default.
• W2088130488 cites W1967640947 @default.
• W2088130488 cites W1967852178 @default.
• W2088130488 cites W1969092065 @default.
• W2088130488 cites W1991078747 @default.
• W2088130488 cites W1995647160 @default.
• W2088130488 cites W1998231921 @default.
• W2088130488 cites W2064324964 @default.
• W2088130488 cites W2077868231 @default.
• W2088130488 cites W2086916290 @default.
• W2088130488 cites W2097813811 @default.
• W2088130488 cites W2103553099 @default.
• W2088130488 cites W2105009731 @default.
• W2088130488 cites W2144387904 @default.
• W2088130488 cites W2145198531 @default.
• W2088130488 cites W2150105784 @default.
• W2088130488 cites W2153170511 @default.
• W2088130488 cites W4251551022 @default.
• W2088130488 doi "https://doi.org/10.1016/j.bcmd.2012.04.002" @default.
• W2088130488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22560483" @default.
• W2088130488 hasPublicationYear "2012" @default.
• W2088130488 type Work @default.
• W2088130488 sameAs 2088130488 @default.
• W2088130488 citedByCount "32" @default.
• W2088130488 countsByYear W20881304882012 @default.
• W2088130488 countsByYear W20881304882013 @default.
• W2088130488 countsByYear W20881304882014 @default.
• W2088130488 countsByYear W20881304882015 @default.
• W2088130488 countsByYear W20881304882016 @default.
• W2088130488 countsByYear W20881304882017 @default.
• W2088130488 countsByYear W20881304882018 @default.
• W2088130488 countsByYear W20881304882019 @default.
• W2088130488 countsByYear W20881304882020 @default.
• W2088130488 countsByYear W20881304882021 @default.
• W2088130488 countsByYear W20881304882022 @default.
• W2088130488 countsByYear W20881304882023 @default.
• W2088130488 crossrefType "journal-article" @default.
• W2088130488 hasAuthorship W2088130488A5032207811 @default.
• W2088130488 hasAuthorship W2088130488A5032873950 @default.
• W2088130488 hasAuthorship W2088130488A5041077575 @default.
• W2088130488 hasAuthorship W2088130488A5042547987 @default.
• W2088130488 hasAuthorship W2088130488A5055335263 @default.
• W2088130488 hasAuthorship W2088130488A5069537100 @default.
• W2088130488 hasAuthorship W2088130488A5074956599 @default.
• W2088130488 hasAuthorship W2088130488A5087386909 @default.
• W2088130488 hasConcept C126322002 @default.
• W2088130488 hasConcept C134018914 @default.
• W2088130488 hasConcept C153852466 @default.
• W2088130488 hasConcept C22814914 @default.
• W2088130488 hasConcept C2777513400 @default.
• W2088130488 hasConcept C2778319317 @default.
• W2088130488 hasConcept C2779134260 @default.
• W2088130488 hasConcept C2779969927 @default.
• W2088130488 hasConcept C3019184707 @default.
• W2088130488 hasConcept C71924100 @default.
• W2088130488 hasConcept C90924648 @default.
• W2088130488 hasConceptScore W2088130488C126322002 @default.
• W2088130488 hasConceptScore W2088130488C134018914 @default.
• W2088130488 hasConceptScore W2088130488C153852466 @default.
• W2088130488 hasConceptScore W2088130488C22814914 @default.
• W2088130488 hasConceptScore W2088130488C2777513400 @default.
• W2088130488 hasConceptScore W2088130488C2778319317 @default.
• W2088130488 hasConceptScore W2088130488C2779134260 @default.
• W2088130488 hasConceptScore W2088130488C2779969927 @default.
• W2088130488 hasConceptScore W2088130488C3019184707 @default.
• W2088130488 hasConceptScore W2088130488C71924100 @default.
• W2088130488 hasConceptScore W2088130488C90924648 @default.
• W2088130488 hasIssue "1" @default.
• W2088130488 hasLocation W20881304881 @default.
• W2088130488 hasLocation W20881304882 @default.
• W2088130488 hasOpenAccess W2088130488 @default.
• W2088130488 hasPrimaryLocation W20881304881 @default.
• W2088130488 hasRelatedWork W2022305411 @default.
• W2088130488 hasRelatedWork W2058210237 @default.
• W2088130488 hasRelatedWork W2086863876 @default.
• W2088130488 hasRelatedWork W2088130488 @default.
• W2088130488 hasRelatedWork W2102868472 @default.
• W2088130488 hasRelatedWork W2168580393 @default.
• W2088130488 hasRelatedWork W2996970448 @default.
• W2088130488 hasRelatedWork W3117776092 @default.
• W2088130488 hasRelatedWork W4224919177 @default.
• W2088130488 hasRelatedWork W4295528242 @default.
• W2088130488 hasVolume "49" @default.
• W2088130488 isParatext "false" @default.
• W2088130488 isRetracted "false" @default.
• W2088130488 magId "2088130488" @default.

• next