Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088157788> ?p ?o ?g. }
- W2088157788 endingPage "2031" @default.
- W2088157788 startingPage "2023" @default.
- W2088157788 abstract "Better assessment of the association between cardiovascular disease and osteoporosis in older men may help identify shared etiologies for bone and heart health in this population. We assessed the association of BMD and bone turnover markers (BTMs) with risk of cardiovascular events (myocardial infarction or stroke) in 744 men ≥50 yr of age. During the 7.5-yr prospective follow-up, 43 strokes and 40 myocardial infarctions occurred in 79 men. After adjustment for confounders (age, weight, height, smoking, education, physical activity, self-reported history of diabetes, hypertension, and prevalent ischemic heart disease), men in the lowest quartile of BMD at the spine, whole body, and forearm had a 2-fold increased risk of cardiovascular events. Men in the highest quartile of bone resorption markers (deoxypyridinoline [DPD], C-telopeptide of type I collagen) had a 2-fold increased risk of cardiovascular events (e.g., multivariable-adjusted hazard ratio [including additional adjustment for BMD] was 2.11 [95% CI: 1.26–3.56], for the highest quartile of free DPD relative to the lowest three quartiles). The results were similar for men without prevalent ischemic heart disease and for myocardial infarction and stroke analyzed separately. Our data suggest that men with low BMD or high bone resorption may be at increased risk of myocardial infarction and stroke in addition to fracture. Thus, men with osteoporosis may benefit from screening for cardiovascular disease. Further study to elucidate the biological mechanism shared by bone and vascular disease may help efforts to identify men at risk or develop treatment." @default.
- W2088157788 created "2016-06-24" @default.
- W2088157788 creator A5002843087 @default.
- W2088157788 creator A5013115644 @default.
- W2088157788 creator A5045187968 @default.
- W2088157788 creator A5054458876 @default.
- W2088157788 date "2009-12-01" @default.
- W2088157788 modified "2023-10-05" @default.
- W2088157788 title "Increased Bone Resorption Is Associated With Increased Risk of Cardiovascular Events in Men: The MINOS Study" @default.
- W2088157788 cites W1527588610 @default.
- W2088157788 cites W1535266121 @default.
- W2088157788 cites W1550493347 @default.
- W2088157788 cites W1551452776 @default.
- W2088157788 cites W1793674463 @default.
- W2088157788 cites W1963676489 @default.
- W2088157788 cites W1966766074 @default.
- W2088157788 cites W1969654155 @default.
- W2088157788 cites W1970142610 @default.
- W2088157788 cites W1972584749 @default.
- W2088157788 cites W1999703499 @default.
- W2088157788 cites W2003904705 @default.
- W2088157788 cites W2006700402 @default.
- W2088157788 cites W2012865835 @default.
- W2088157788 cites W2015536677 @default.
- W2088157788 cites W2015571962 @default.
- W2088157788 cites W2019691840 @default.
- W2088157788 cites W2024542225 @default.
- W2088157788 cites W2025994623 @default.
- W2088157788 cites W2031390524 @default.
- W2088157788 cites W2034959911 @default.
- W2088157788 cites W2035139971 @default.
- W2088157788 cites W2048605574 @default.
- W2088157788 cites W2051268983 @default.
- W2088157788 cites W2051702994 @default.
- W2088157788 cites W2054797498 @default.
- W2088157788 cites W2057195839 @default.
- W2088157788 cites W2058579856 @default.
- W2088157788 cites W2058709767 @default.
- W2088157788 cites W2059188644 @default.
- W2088157788 cites W2061884525 @default.
- W2088157788 cites W2062511941 @default.
- W2088157788 cites W2062764979 @default.
- W2088157788 cites W2067325834 @default.
- W2088157788 cites W2067504868 @default.
- W2088157788 cites W2069891069 @default.
- W2088157788 cites W2076067955 @default.
- W2088157788 cites W2077006024 @default.
- W2088157788 cites W2086447342 @default.
- W2088157788 cites W2101051981 @default.
- W2088157788 cites W2103241766 @default.
- W2088157788 cites W2104127478 @default.
- W2088157788 cites W2108859807 @default.
- W2088157788 cites W2109539718 @default.
- W2088157788 cites W2111674612 @default.
- W2088157788 cites W2113748378 @default.
- W2088157788 cites W2118835331 @default.
- W2088157788 cites W2125983743 @default.
- W2088157788 cites W2127454781 @default.
- W2088157788 cites W2128843508 @default.
- W2088157788 cites W2137188853 @default.
- W2088157788 cites W2151667145 @default.
- W2088157788 cites W2157242620 @default.
- W2088157788 cites W2159635135 @default.
- W2088157788 cites W2165698743 @default.
- W2088157788 cites W2167455623 @default.
- W2088157788 cites W2170486369 @default.
- W2088157788 cites W2171074879 @default.
- W2088157788 cites W2331280127 @default.
- W2088157788 cites W2398359567 @default.
- W2088157788 cites W3147351840 @default.
- W2088157788 doi "https://doi.org/10.1359/jbmr.090531" @default.
- W2088157788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2791516" @default.
- W2088157788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19453264" @default.
- W2088157788 hasPublicationYear "2009" @default.
- W2088157788 type Work @default.
- W2088157788 sameAs 2088157788 @default.
- W2088157788 citedByCount "54" @default.
- W2088157788 countsByYear W20881577882012 @default.
- W2088157788 countsByYear W20881577882013 @default.
- W2088157788 countsByYear W20881577882014 @default.
- W2088157788 countsByYear W20881577882015 @default.
- W2088157788 countsByYear W20881577882016 @default.
- W2088157788 countsByYear W20881577882017 @default.
- W2088157788 countsByYear W20881577882018 @default.
- W2088157788 countsByYear W20881577882019 @default.
- W2088157788 countsByYear W20881577882020 @default.
- W2088157788 countsByYear W20881577882021 @default.
- W2088157788 countsByYear W20881577882022 @default.
- W2088157788 countsByYear W20881577882023 @default.
- W2088157788 crossrefType "journal-article" @default.
- W2088157788 hasAuthorship W2088157788A5002843087 @default.
- W2088157788 hasAuthorship W2088157788A5013115644 @default.
- W2088157788 hasAuthorship W2088157788A5045187968 @default.
- W2088157788 hasAuthorship W2088157788A5054458876 @default.
- W2088157788 hasBestOaLocation W20881577881 @default.
- W2088157788 hasConcept C126322002 @default.
- W2088157788 hasConcept C127413603 @default.
- W2088157788 hasConcept C134018914 @default.