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- W2088171495 abstract "Introduction The intra-aortic administration of concentrated radiopaque agents is an established diagnostic technique. Complications are rare, but when they occur the kidney is most frequently involved. 1 The mechanism of toxicity remains obscure. Considerable evidence has been presented 2 to support a direct parenchymal effect. However, vasospasm, either arterial 3 or venous, 4 has been reported suggesting that renal damage is secondary to ischemia. The purpose of the present investigation was to determine the influence of various perfusates on the hemodynamic response of the canine kidney to angiographic media, since in previous experimental studies 5 vascular obstruction arising from markedly hypertonic solutions including contrast agents was found to be related to the presence of the red cell. Materials and Methods 1. Renal Perfusion Studies. —Adult mongrel dogs were anesthetized by the intravenous administration of pentobarbital sodium, 30 mg/kg body weight. A midline laparotomy was performed and the left kidney removed." @default.
- W2088171495 created "2016-06-24" @default.
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- W2088171495 date "1964-05-01" @default.
- W2088171495 modified "2023-09-24" @default.
- W2088171495 title "Renal Damage From Angiographic Media" @default.
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- W2088171495 doi "https://doi.org/10.1001/archsurg.1964.01310230088019" @default.
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