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• W2088173400 abstract "In Brief Study Design. Comparative, prospective follow-up study. Objective. Comparison of outcome between patients treated with Percutaneous VertebroPlasty (PVP) using low and medium viscosity PolyMethylMetAcrylate (PMMA) bone cement. Summary of Background Data. Viscosity is the characterizing parameter of PMMA bone cement, currently the standard augmentation material in PVP, and influences interdigitation, cement distribution inside the vertebral body, injected volume and extravasation, thereby affecting the clinical outcome of PVP. Currently, low, medium, and high viscosity PMMA bone cements are used interchangeably. However, effect of viscosity on clinical outcome in patients with Osteoporotic Vertebral Compression Fractures (OVCFs) has not yet been explicit subject of investigation. Methods. Follow-up was conducted using a 0 to 10 Pain Intensity Numerical Rating Scale (PI-NRS) and the Short Form 36 (SF-36) Quality of Life questionnaire before PVP and at 7 days (PI-NRS only), 1, 3, and 12 months after PVP. Injected cement volume, degree of interdigitation, and cement leakage were analyzed on direct postoperative computed tomography scanning. At 6 and 52 weeks and at suspicion, patients were analyzed for new fractures. Results. A total of 30 consecutive patients received PVP using low viscosity PMMA bone cement (OsteoPal-V) for 62 OVCFs, followed by 34 patients who received PVP using medium viscosity PMMA bone cement (Disc-O-Tech) for 67 OVCFs. Results regarding PI-NRS and SF-36 were comparable between both groups. Postoperative comparison of injected cement volume, degree of interdigitation, proportion of bipedicular procedures, incidence of new vertebral fractures and complications revealed no differences between both groups. Viscosity was identified as a risk factor for the occurrence of cement leakage (yes/no, OR: 2.925, 95% confidence interval: [1.072-7.984], P = 0.036). Conclusion. No major differences in clinical outcome after PVP in OVCFs using low and medium viscosity PMMA bone cement were found. Viscosity of PMMA bone cement was identified as an independent predictor of cement leakage. This is the first study to explicitly investigate the in vivo effect of PolyMethylMetAcrylate bone cement viscosity on clinical outcome after percutaneous vertebroplasty. No major differences in clinical outcome after percutaneous vertebroplasty using low and medium viscosity PolyMethylMetAcrylate bone cement were found. Viscosity was identified as an independent predictor of cement extravasation." @default.
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• W2088173400 date "2010-09-01" @default.
• W2088173400 modified "2023-09-25" @default.
• W2088173400 title "A Clinical Comparative Study on Low Versus Medium Viscosity PolyMethylMetAcrylate Bone Cement in Percutaneous Vertebroplasty" @default.
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• W2088173400 doi "https://doi.org/10.1097/brs.0b013e3181ddd262" @default.
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