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- W2088228295 abstract "This study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>μ</mml:mi></mml:math>A/2 min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mrow><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>.05</mml:mn></mml:mrow></mml:math>), with positive effects on the area of newly formed tissue, number of fibroblasts, number of newly formed blood vessels, and epithelial thickness. Morphometric data confirmed the structural findings. The O. flexuosum leaf extract contains active compounds that speed the healing process, especially when applied simultaneously with microcurrent stimulation." @default.
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- W2088228295 date "2011-01-01" @default.
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- W2088228295 title "Effects of the Topical Application of Hydroalcoholic Leaf Extract of<i>Oncidium flexuosum</i>Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in<i>Wistar</i>Rats" @default.
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- W2088228295 doi "https://doi.org/10.1155/2011/950347" @default.
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