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- W2088249531 abstract "Sixty-three addicts were given heroin intravenously at a rate of 20–40 mg/2 cc/ 2 min, and 8–32 min later received 1–2 mg naloxone. The EEG was recorded in the preheroin, post-heroin and post-naloxone periods. The early response to heroin (first 4 min after the start of the injection) was an increase in alpha amplitudes, decrease of alpha frequency and an occasional increase in alpha spindling. The late response (5–32 min after the start of the injection) was a decrease in alpha abundance, an increase in theta and sometimes delta activities, and paroxysmal EEG activity. Two clinical seizures were seen. The tracings returned to the pre-heroin pattern after the administration of naloxone. These observations of heroin and naloxone are consistent with established theories of association of EEG and behavior in man after psychoactive drugs." @default.
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- W2088249531 date "1970-11-01" @default.
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- W2088249531 title "Electrographic effects of diacetylmorphine (heroin) and naloxone in man" @default.
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- W2088249531 doi "https://doi.org/10.1016/0028-3908(70)90009-2" @default.
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