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- W2088252359 abstract "Pentaerythritol (2,2-bis-hydroxymethyl-propane-1,3-diol) was converted into a series of mono-, di-, and trisubstituted derivatives, comprising allyl ethers and amino-alkyl ethers, by systematic chemical manipulation of the hydroxy groups. The remaining hydroxymethyl group in the case of the trisubstituted analog was functionalized with ether groups bearing terminal ω-carboxyl or ω-alkene groups. These derivatives are versatile templates and scaffolds for single, double, or triple substitution with appropriate ligands forming amides and esters, and allowing the attachment of the ω-alkene or ω-carboxyl group to solid support for combinatorial chemistry. Key words: molecular diversity, scaffolds, templates and tris(2-aminoethyl)-pentaerythritol." @default.
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- W2088252359 date "1996-09-01" @default.
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- W2088252359 title "Synthesis of chemically and functionally diverse scaffolds from pentaerythritol" @default.
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- W2088252359 doi "https://doi.org/10.1139/v96-191" @default.
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