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• W2088262418 abstract "A circadian clock regulates a number of diverse physiological functions in the vertebrate eye. In this study, we show that mRNA for the red-sensitive cone pigment, iodopsin, fluctuates with a circadian rhythm in chicken retina. Transcript levels increase in the late afternoon just prior to the time of cone disc shedding. Furthermore, iodopsin mRNA levels are regulated similarly by a circadian oscillator in primary cultures of dispersed embryonic chick retina. Nuclear run-on experiments show that the circadian regulation of iodopsin transcript abundance occurs at the level of gene transcription. Our results provide a demonstration of clock-regulated gene expression in a vertebrate preparation maintained in cell culture." @default.
• W2088262418 created "2016-06-24" @default.
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• W2088262418 date "1993-04-01" @default.
• W2088262418 modified "2023-09-26" @default.
• W2088262418 title "Circadian regulation of lodopsin gene expression in embryonic photoreceptors in retinal cell culture" @default.
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• W2088262418 doi "https://doi.org/10.1016/0896-6273(93)90161-j" @default.
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