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- W2088270029 abstract "This short review addresses modern concepts of oxygen transport and utilization. It consists of two sections. The first deals with the underlying concepts and is largely theoretical. It first presents the transport pathway components as a linked in series system. Then, the way in which the components are integrated to set limits to overall O2 availability to tissue mitochondria is discussed. It therefore presents a framework for interpreting O2 transport limitations, both in health and disease. The second section deals with experimental outcomes of studies that address the pathway components and the limitations they may impose on O2 availability using that framework. Most of these studies have involved exercise in healthy subjects, but some have examined the relationship between O2 supply and utilization in critically ill patients. An application suitable for intact transgenic mouse phenotyping studies is also proposed." @default.
- W2088270029 created "2016-06-24" @default.
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- W2088270029 date "2008-01-10" @default.
- W2088270029 modified "2023-10-18" @default.
- W2088270029 title "Systemic oxygen transport and utilization" @default.
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- W2088270029 doi "https://doi.org/10.1088/1752-7155/2/2/024001" @default.
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