Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088291857> ?p ?o ?g. }
- W2088291857 endingPage "286" @default.
- W2088291857 startingPage "282" @default.
- W2088291857 abstract "Summary. Platelets are highly responsive to signals from their environment. The sensing and processing of some of these stimuli are mediated by G-protein signal transduction cascades. It is well established that proteins involved in signal transduction may be targets for naturally occurring mutations resulting in human diseases. The best-studied molecules in platelets in relation to disease are the G-protein coupled receptors being the most platelet-specific. Many of the other signal transduction genes are often not only present in platelets but also in other tissues. Therefore, the clinical phenotype of signaling defects in platelets, apart from the membrane receptor defects, is seldom isolated to a hemostatic phenotype. Moreover, as platelets are easily accessible cells, and one of the best-studied models regarding signaling, platelets are easily applicable to investigate defects in ubiquitously expressed genes. Apart from a discussion on classical thrombopathies, this review will also deal with the less commonly known relation between platelet signaling defects and disorders with a broader clinical phenotype." @default.
- W2088291857 created "2016-06-24" @default.
- W2088291857 creator A5030746368 @default.
- W2088291857 creator A5056676933 @default.
- W2088291857 creator A5064832605 @default.
- W2088291857 creator A5078978029 @default.
- W2088291857 date "2009-07-01" @default.
- W2088291857 modified "2023-10-04" @default.
- W2088291857 title "Human platelet pathology related to defects in the G-protein signaling cascade" @default.
- W2088291857 cites W1490772051 @default.
- W2088291857 cites W1567363998 @default.
- W2088291857 cites W1657825487 @default.
- W2088291857 cites W1879519963 @default.
- W2088291857 cites W1899700659 @default.
- W2088291857 cites W1913178294 @default.
- W2088291857 cites W1977493444 @default.
- W2088291857 cites W1982733325 @default.
- W2088291857 cites W1984212762 @default.
- W2088291857 cites W1990996373 @default.
- W2088291857 cites W1998609280 @default.
- W2088291857 cites W2002409738 @default.
- W2088291857 cites W2003029294 @default.
- W2088291857 cites W2003440775 @default.
- W2088291857 cites W2015589757 @default.
- W2088291857 cites W2016217548 @default.
- W2088291857 cites W2017450138 @default.
- W2088291857 cites W2019738984 @default.
- W2088291857 cites W2027256014 @default.
- W2088291857 cites W2030625703 @default.
- W2088291857 cites W2034083722 @default.
- W2088291857 cites W2051461646 @default.
- W2088291857 cites W2053074918 @default.
- W2088291857 cites W2054295839 @default.
- W2088291857 cites W2095013577 @default.
- W2088291857 cites W2105624967 @default.
- W2088291857 cites W2123343810 @default.
- W2088291857 cites W212830756 @default.
- W2088291857 cites W2132523777 @default.
- W2088291857 cites W2134723230 @default.
- W2088291857 cites W2135582045 @default.
- W2088291857 cites W2143442358 @default.
- W2088291857 cites W2150641842 @default.
- W2088291857 cites W2161488081 @default.
- W2088291857 cites W2218657236 @default.
- W2088291857 cites W2265371507 @default.
- W2088291857 cites W2469645070 @default.
- W2088291857 cites W2519967868 @default.
- W2088291857 cites W4239058305 @default.
- W2088291857 doi "https://doi.org/10.1111/j.1538-7836.2009.03399.x" @default.
- W2088291857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19630817" @default.
- W2088291857 hasPublicationYear "2009" @default.
- W2088291857 type Work @default.
- W2088291857 sameAs 2088291857 @default.
- W2088291857 citedByCount "25" @default.
- W2088291857 countsByYear W20882918572012 @default.
- W2088291857 countsByYear W20882918572013 @default.
- W2088291857 countsByYear W20882918572014 @default.
- W2088291857 countsByYear W20882918572015 @default.
- W2088291857 countsByYear W20882918572016 @default.
- W2088291857 countsByYear W20882918572017 @default.
- W2088291857 countsByYear W20882918572018 @default.
- W2088291857 countsByYear W20882918572019 @default.
- W2088291857 countsByYear W20882918572022 @default.
- W2088291857 crossrefType "journal-article" @default.
- W2088291857 hasAuthorship W2088291857A5030746368 @default.
- W2088291857 hasAuthorship W2088291857A5056676933 @default.
- W2088291857 hasAuthorship W2088291857A5064832605 @default.
- W2088291857 hasAuthorship W2088291857A5078978029 @default.
- W2088291857 hasConcept C104317684 @default.
- W2088291857 hasConcept C127716648 @default.
- W2088291857 hasConcept C15152581 @default.
- W2088291857 hasConcept C170493617 @default.
- W2088291857 hasConcept C197462201 @default.
- W2088291857 hasConcept C203014093 @default.
- W2088291857 hasConcept C3018697912 @default.
- W2088291857 hasConcept C54355233 @default.
- W2088291857 hasConcept C55493867 @default.
- W2088291857 hasConcept C62478195 @default.
- W2088291857 hasConcept C86803240 @default.
- W2088291857 hasConcept C89560881 @default.
- W2088291857 hasConcept C95444343 @default.
- W2088291857 hasConceptScore W2088291857C104317684 @default.
- W2088291857 hasConceptScore W2088291857C127716648 @default.
- W2088291857 hasConceptScore W2088291857C15152581 @default.
- W2088291857 hasConceptScore W2088291857C170493617 @default.
- W2088291857 hasConceptScore W2088291857C197462201 @default.
- W2088291857 hasConceptScore W2088291857C203014093 @default.
- W2088291857 hasConceptScore W2088291857C3018697912 @default.
- W2088291857 hasConceptScore W2088291857C54355233 @default.
- W2088291857 hasConceptScore W2088291857C55493867 @default.
- W2088291857 hasConceptScore W2088291857C62478195 @default.
- W2088291857 hasConceptScore W2088291857C86803240 @default.
- W2088291857 hasConceptScore W2088291857C89560881 @default.
- W2088291857 hasConceptScore W2088291857C95444343 @default.
- W2088291857 hasLocation W20882918571 @default.
- W2088291857 hasLocation W20882918572 @default.
- W2088291857 hasOpenAccess W2088291857 @default.
- W2088291857 hasPrimaryLocation W20882918571 @default.