Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088367057> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2088367057 endingPage "227" @default.
- W2088367057 startingPage "219" @default.
- W2088367057 abstract "An analysis of prospectively collected data from 75 patients with bone metastases secondary to prostate cancer who were treated with strontium-89 injection in a single centre over a 10-year period, is presented. The surrogate role of markers of disease progression (haemoglobin and prostate specific (PSA) antigen levels; number of bone scan-positive sites), symptomatic factors (analgesic intake; number of painful bone sites) and history of prior external radiotherapy, were analysed to determine whether any parameters had a predictive effect on the success of strontium-89 treatment. The success of strontium-89 injection was determined by calculating the change in number of sites of bone pain (pain sites) and analgesic intake. The outcome was classed as successful in 42 (56.0%) patients, unsuccessful in 13 (17.3%) and unchanged in 20 (26.7%). Proportionately more of the patients who had ‘superscans’ on bone scintigraphy at baseline had an unsuccessful outcome after a strontium-89 injection (5/7; 71.4%); for those with fewer bone scan-positive sites the majority had successful outcomes. Patients with a successful outcome had a significantly better survival rate after strontium- 89 injection. Multivariate analysis showed haemoglobin level, PSA level and outcome after strontium-89 treatment to be significant independent prognostic variables; no change/unsuccessful outcome, a high PSA level prior to treatment, and a low haemoglobin level were associated with poor survival. It is suggested that early treatment with strontium-89 (Metastron®) in patients with fewer bone metastases is more likely to be successful, with a longer time before further therapy required." @default.
- W2088367057 created "2016-06-24" @default.
- W2088367057 creator A5072981537 @default.
- W2088367057 date "2001-06-01" @default.
- W2088367057 modified "2023-09-26" @default.
- W2088367057 title "Predictors of Response to Strontium-89 (Metastron®) in Skeletal Metastases from Prostate Cancer: Report of a Single Centre's 10-Year Experience" @default.
- W2088367057 cites W1963635251 @default.
- W2088367057 cites W1983514189 @default.
- W2088367057 cites W1986961751 @default.
- W2088367057 cites W1990718568 @default.
- W2088367057 cites W1994309595 @default.
- W2088367057 cites W1995975133 @default.
- W2088367057 cites W2007493031 @default.
- W2088367057 cites W2058825665 @default.
- W2088367057 cites W2066553392 @default.
- W2088367057 cites W2070408871 @default.
- W2088367057 cites W2073955285 @default.
- W2088367057 cites W2092389226 @default.
- W2088367057 cites W2130484646 @default.
- W2088367057 cites W2142814605 @default.
- W2088367057 cites W2417467422 @default.
- W2088367057 doi "https://doi.org/10.1053/clon.2001.9257" @default.
- W2088367057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11527299" @default.
- W2088367057 hasPublicationYear "2001" @default.
- W2088367057 type Work @default.
- W2088367057 sameAs 2088367057 @default.
- W2088367057 citedByCount "13" @default.
- W2088367057 countsByYear W20883670572012 @default.
- W2088367057 countsByYear W20883670572013 @default.
- W2088367057 countsByYear W20883670572014 @default.
- W2088367057 countsByYear W20883670572015 @default.
- W2088367057 countsByYear W20883670572016 @default.
- W2088367057 countsByYear W20883670572023 @default.
- W2088367057 crossrefType "journal-article" @default.
- W2088367057 hasAuthorship W2088367057A5072981537 @default.
- W2088367057 hasConcept C121332964 @default.
- W2088367057 hasConcept C121608353 @default.
- W2088367057 hasConcept C126322002 @default.
- W2088367057 hasConcept C126894567 @default.
- W2088367057 hasConcept C141071460 @default.
- W2088367057 hasConcept C143998085 @default.
- W2088367057 hasConcept C185544564 @default.
- W2088367057 hasConcept C2776049877 @default.
- W2088367057 hasConcept C2776235491 @default.
- W2088367057 hasConcept C2780192828 @default.
- W2088367057 hasConcept C2780820201 @default.
- W2088367057 hasConcept C2781406297 @default.
- W2088367057 hasConcept C2989005 @default.
- W2088367057 hasConcept C38180746 @default.
- W2088367057 hasConcept C42219234 @default.
- W2088367057 hasConcept C509974204 @default.
- W2088367057 hasConcept C518915863 @default.
- W2088367057 hasConcept C71924100 @default.
- W2088367057 hasConceptScore W2088367057C121332964 @default.
- W2088367057 hasConceptScore W2088367057C121608353 @default.
- W2088367057 hasConceptScore W2088367057C126322002 @default.
- W2088367057 hasConceptScore W2088367057C126894567 @default.
- W2088367057 hasConceptScore W2088367057C141071460 @default.
- W2088367057 hasConceptScore W2088367057C143998085 @default.
- W2088367057 hasConceptScore W2088367057C185544564 @default.
- W2088367057 hasConceptScore W2088367057C2776049877 @default.
- W2088367057 hasConceptScore W2088367057C2776235491 @default.
- W2088367057 hasConceptScore W2088367057C2780192828 @default.
- W2088367057 hasConceptScore W2088367057C2780820201 @default.
- W2088367057 hasConceptScore W2088367057C2781406297 @default.
- W2088367057 hasConceptScore W2088367057C2989005 @default.
- W2088367057 hasConceptScore W2088367057C38180746 @default.
- W2088367057 hasConceptScore W2088367057C42219234 @default.
- W2088367057 hasConceptScore W2088367057C509974204 @default.
- W2088367057 hasConceptScore W2088367057C518915863 @default.
- W2088367057 hasConceptScore W2088367057C71924100 @default.
- W2088367057 hasIssue "3" @default.
- W2088367057 hasLocation W20883670571 @default.
- W2088367057 hasLocation W20883670572 @default.
- W2088367057 hasOpenAccess W2088367057 @default.
- W2088367057 hasPrimaryLocation W20883670571 @default.
- W2088367057 hasRelatedWork W1980188241 @default.
- W2088367057 hasRelatedWork W1982816235 @default.
- W2088367057 hasRelatedWork W2038565121 @default.
- W2088367057 hasRelatedWork W2042911820 @default.
- W2088367057 hasRelatedWork W2074491453 @default.
- W2088367057 hasRelatedWork W2084319043 @default.
- W2088367057 hasRelatedWork W2129795405 @default.
- W2088367057 hasRelatedWork W2152050874 @default.
- W2088367057 hasRelatedWork W2393285311 @default.
- W2088367057 hasRelatedWork W2897445903 @default.
- W2088367057 hasVolume "13" @default.
- W2088367057 isParatext "false" @default.
- W2088367057 isRetracted "false" @default.
- W2088367057 magId "2088367057" @default.
- W2088367057 workType "article" @default.