FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088384080> ?p ?o ?g. }

• W2088384080 endingPage "200" @default.
• W2088384080 startingPage "196" @default.
• W2088384080 abstract "Whole-cell patch-clamp was used to assess the modulatory effect of thiopental (Thio) on glycine (Gly) receptor in mechanically dissociated rat spinal dorsal horn neurons. It was found that Thio inhibited the amplitude, accelerated the desensitization and prolonged the deactivation of Gly-induced currents (IGly) in a concentration-dependent manner. In addition, a rebound current occurred after washout of the co-application of Gly and Thio in most neurons tested. Moreover, the inhibitory effect of Thio was not the result of cross-inhibition between Gly and GABAA receptors. Furthermore, taurine-induced currents, a low-affinity agonist for Gly receptors, were also markedly inhibited by Thio in a similar way to IGly. These results indicate that Thio suppresses Gly receptor function and suggest that Thio anesthetic actions might not be mediated by Gly receptors. We speculate that the weak muscle relaxation and the limited analgesic effects observed during Thio anesthesia may attribute to its inhibitory effects on Gly receptors." @default.
• W2088384080 created "2016-06-24" @default.
• W2088384080 creator A5008166482 @default.
• W2088384080 creator A5080465353 @default.
• W2088384080 date "2006-04-01" @default.
• W2088384080 modified "2023-10-13" @default.
• W2088384080 title "Thiopental inhibits glycine receptor function in acutely dissociated rat spinal dorsal horn neurons" @default.
• W2088384080 cites W1827031147 @default.
• W2088384080 cites W1871839128 @default.
• W2088384080 cites W1968895385 @default.
• W2088384080 cites W1969640231 @default.
• W2088384080 cites W1972287815 @default.
• W2088384080 cites W1980983414 @default.
• W2088384080 cites W2014855154 @default.
• W2088384080 cites W2022158067 @default.
• W2088384080 cites W2023730096 @default.
• W2088384080 cites W2029877737 @default.
• W2088384080 cites W2036635378 @default.
• W2088384080 cites W2045221743 @default.
• W2088384080 cites W2049184249 @default.
• W2088384080 cites W2053480499 @default.
• W2088384080 cites W2062226595 @default.
• W2088384080 cites W2083106679 @default.
• W2088384080 cites W2102763903 @default.
• W2088384080 cites W2110107835 @default.
• W2088384080 cites W2117449859 @default.
• W2088384080 cites W2117474212 @default.
• W2088384080 cites W2156969997 @default.
• W2088384080 doi "https://doi.org/10.1016/j.neulet.2005.12.020" @default.
• W2088384080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16406669" @default.
• W2088384080 hasPublicationYear "2006" @default.
• W2088384080 type Work @default.
• W2088384080 sameAs 2088384080 @default.
• W2088384080 citedByCount "2" @default.
• W2088384080 countsByYear W20883840802014 @default.
• W2088384080 countsByYear W20883840802020 @default.
• W2088384080 crossrefType "journal-article" @default.
• W2088384080 hasAuthorship W2088384080A5008166482 @default.
• W2088384080 hasAuthorship W2088384080A5080465353 @default.
• W2088384080 hasConcept C126322002 @default.
• W2088384080 hasConcept C134018914 @default.
• W2088384080 hasConcept C147944092 @default.
• W2088384080 hasConcept C168258287 @default.
• W2088384080 hasConcept C169760540 @default.
• W2088384080 hasConcept C170493617 @default.
• W2088384080 hasConcept C17077164 @default.
• W2088384080 hasConcept C185592680 @default.
• W2088384080 hasConcept C2777756961 @default.
• W2088384080 hasConcept C2778938600 @default.
• W2088384080 hasConcept C2779701627 @default.
• W2088384080 hasConcept C2779779143 @default.
• W2088384080 hasConcept C2781253882 @default.
• W2088384080 hasConcept C35599011 @default.
• W2088384080 hasConcept C515207424 @default.
• W2088384080 hasConcept C55493867 @default.
• W2088384080 hasConcept C71240020 @default.
• W2088384080 hasConcept C71924100 @default.
• W2088384080 hasConcept C86803240 @default.
• W2088384080 hasConcept C98274493 @default.
• W2088384080 hasConceptScore W2088384080C126322002 @default.
• W2088384080 hasConceptScore W2088384080C134018914 @default.
• W2088384080 hasConceptScore W2088384080C147944092 @default.
• W2088384080 hasConceptScore W2088384080C168258287 @default.
• W2088384080 hasConceptScore W2088384080C169760540 @default.
• W2088384080 hasConceptScore W2088384080C170493617 @default.
• W2088384080 hasConceptScore W2088384080C17077164 @default.
• W2088384080 hasConceptScore W2088384080C185592680 @default.
• W2088384080 hasConceptScore W2088384080C2777756961 @default.
• W2088384080 hasConceptScore W2088384080C2778938600 @default.
• W2088384080 hasConceptScore W2088384080C2779701627 @default.
• W2088384080 hasConceptScore W2088384080C2779779143 @default.
• W2088384080 hasConceptScore W2088384080C2781253882 @default.
• W2088384080 hasConceptScore W2088384080C35599011 @default.
• W2088384080 hasConceptScore W2088384080C515207424 @default.
• W2088384080 hasConceptScore W2088384080C55493867 @default.
• W2088384080 hasConceptScore W2088384080C71240020 @default.
• W2088384080 hasConceptScore W2088384080C71924100 @default.
• W2088384080 hasConceptScore W2088384080C86803240 @default.
• W2088384080 hasConceptScore W2088384080C98274493 @default.
• W2088384080 hasFunder F4320321001 @default.
• W2088384080 hasFunder F4320335777 @default.
• W2088384080 hasIssue "3" @default.
• W2088384080 hasLocation W20883840801 @default.
• W2088384080 hasLocation W20883840802 @default.
• W2088384080 hasOpenAccess W2088384080 @default.
• W2088384080 hasPrimaryLocation W20883840801 @default.
• W2088384080 hasRelatedWork W1985236527 @default.
• W2088384080 hasRelatedWork W2007578015 @default.
• W2088384080 hasRelatedWork W2019769317 @default.
• W2088384080 hasRelatedWork W2045574104 @default.
• W2088384080 hasRelatedWork W2088384080 @default.
• W2088384080 hasRelatedWork W2108265031 @default.
• W2088384080 hasRelatedWork W2113270041 @default.
• W2088384080 hasRelatedWork W2198504477 @default.
• W2088384080 hasRelatedWork W2245630575 @default.
• W2088384080 hasRelatedWork W2396823435 @default.
• W2088384080 hasVolume "397" @default.
• W2088384080 isParatext "false" @default.

• next