FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088391621> ?p ?o ?g. }

• W2088391621 endingPage "198" @default.
• W2088391621 startingPage "193" @default.
• W2088391621 abstract "Provision of Ca2+ for egg shell calcification in the avian uterus [egg shell gland (ESG)] derives mostly from vitamin D-dependent intestinal Ca2+ absorption from the diet. Ca2+ absorption is strongly linked to the intestinal vitamin D-dependent calbindin D28K (D28K) concentration. The laying hen ESG also contains D28K, and again, Ca2+ transport into the shell appeared to be linked to the ESG D28K concentration. However, evidence is now presented that ESG D28K synthesis may be estradiol (E2) dependent and vitamin D independent under certain conditions. One-day-old female chicks fed a vitamin D-free diet for as long as 6 weeks and then repeatedly injected im with E2 for up to 3 more weeks developed frank rickets, but possessed precociously matured reproductive tracts. While the tiny presumptive ESGs of nonestrogenized vitamin D-depleted chicks were devoid of D28K, the highly developed ESG, including the isthmus, of estrogenized chicks contained D28K. The ESGs of nonestrogenized, vitamin D-replete chicks also exhibited no development or detectable D28K. Regardless of whether vitamin D depleted or replete, estrogenized chick ESG contained similar D28K and D28K mRNA concentrations. Immunohistochemical techniques showed that the endometrial cellular localization of both D28K and Ca(2+)-ATPase (Ca2+ pump) in estrogenized chicks was similar to that in mature laying hens. There was no trace of D28K, nor was there any stimulation of Ca2+ absorption, in duodenum of vitamin D-free, immature chicks regardless of E2 treatment. As expected, both D28K and D28K mRNA were present in vitamin D-replete chick duodenum. We conclude that in E2-treated chicks, ESG D28K gene expression may be vitamin D independent and E2 dependent. This is the first clear demonstration of hormone-dependent tissue-specific D28K gene expression in the chick." @default.
• W2088391621 created "2016-06-24" @default.
• W2088391621 creator A5004712720 @default.
• W2088391621 creator A5079146564 @default.
• W2088391621 creator A5083094518 @default.
• W2088391621 creator A5088952309 @default.
• W2088391621 date "1993-01-01" @default.
• W2088391621 modified "2023-09-26" @default.
• W2088391621 title "Tissue-specific regulation of shell gland calbindin D28K biosynthesis by estradiol in precociously matured, vitamin D-depleted chicks." @default.
• W2088391621 cites W1480743860 @default.
• W2088391621 cites W1546500344 @default.
• W2088391621 cites W1579204819 @default.
• W2088391621 cites W1868516327 @default.
• W2088391621 cites W1975386494 @default.
• W2088391621 cites W1987017429 @default.
• W2088391621 cites W1994390711 @default.
• W2088391621 cites W2001345316 @default.
• W2088391621 cites W2014457861 @default.
• W2088391621 cites W2033760486 @default.
• W2088391621 cites W2036943682 @default.
• W2088391621 cites W2048302188 @default.
• W2088391621 cites W2061683571 @default.
• W2088391621 cites W2111740625 @default.
• W2088391621 cites W2161957220 @default.
• W2088391621 cites W2175998906 @default.
• W2088391621 cites W320253653 @default.
• W2088391621 doi "https://doi.org/10.1210/endo.132.1.8419123" @default.
• W2088391621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8419123" @default.
• W2088391621 hasPublicationYear "1993" @default.
• W2088391621 type Work @default.
• W2088391621 sameAs 2088391621 @default.
• W2088391621 citedByCount "22" @default.
• W2088391621 countsByYear W20883916212015 @default.
• W2088391621 countsByYear W20883916212018 @default.
• W2088391621 countsByYear W20883916212021 @default.
• W2088391621 countsByYear W20883916212023 @default.
• W2088391621 crossrefType "journal-article" @default.
• W2088391621 hasAuthorship W2088391621A5004712720 @default.
• W2088391621 hasAuthorship W2088391621A5079146564 @default.
• W2088391621 hasAuthorship W2088391621A5083094518 @default.
• W2088391621 hasAuthorship W2088391621A5088952309 @default.
• W2088391621 hasConcept C124490489 @default.
• W2088391621 hasConcept C126322002 @default.
• W2088391621 hasConcept C134018914 @default.
• W2088391621 hasConcept C185592680 @default.
• W2088391621 hasConcept C18903297 @default.
• W2088391621 hasConcept C195973872 @default.
• W2088391621 hasConcept C2776489590 @default.
• W2088391621 hasConcept C2776809568 @default.
• W2088391621 hasConcept C2776940978 @default.
• W2088391621 hasConcept C2777551382 @default.
• W2088391621 hasConcept C2778004101 @default.
• W2088391621 hasConcept C2779066055 @default.
• W2088391621 hasConcept C55493867 @default.
• W2088391621 hasConcept C71924100 @default.
• W2088391621 hasConcept C86803240 @default.
• W2088391621 hasConceptScore W2088391621C124490489 @default.
• W2088391621 hasConceptScore W2088391621C126322002 @default.
• W2088391621 hasConceptScore W2088391621C134018914 @default.
• W2088391621 hasConceptScore W2088391621C185592680 @default.
• W2088391621 hasConceptScore W2088391621C18903297 @default.
• W2088391621 hasConceptScore W2088391621C195973872 @default.
• W2088391621 hasConceptScore W2088391621C2776489590 @default.
• W2088391621 hasConceptScore W2088391621C2776809568 @default.
• W2088391621 hasConceptScore W2088391621C2776940978 @default.
• W2088391621 hasConceptScore W2088391621C2777551382 @default.
• W2088391621 hasConceptScore W2088391621C2778004101 @default.
• W2088391621 hasConceptScore W2088391621C2779066055 @default.
• W2088391621 hasConceptScore W2088391621C55493867 @default.
• W2088391621 hasConceptScore W2088391621C71924100 @default.
• W2088391621 hasConceptScore W2088391621C86803240 @default.
• W2088391621 hasIssue "1" @default.
• W2088391621 hasLocation W20883916211 @default.
• W2088391621 hasLocation W20883916212 @default.
• W2088391621 hasOpenAccess W2088391621 @default.
• W2088391621 hasPrimaryLocation W20883916211 @default.
• W2088391621 hasRelatedWork W141873526 @default.
• W2088391621 hasRelatedWork W1967386430 @default.
• W2088391621 hasRelatedWork W1969419739 @default.
• W2088391621 hasRelatedWork W1997007826 @default.
• W2088391621 hasRelatedWork W2040672875 @default.
• W2088391621 hasRelatedWork W2091001271 @default.
• W2088391621 hasRelatedWork W2107761980 @default.
• W2088391621 hasRelatedWork W2137013713 @default.
• W2088391621 hasRelatedWork W2149799471 @default.
• W2088391621 hasRelatedWork W4229053620 @default.
• W2088391621 hasVolume "132" @default.
• W2088391621 isParatext "false" @default.
• W2088391621 isRetracted "false" @default.
• W2088391621 magId "2088391621" @default.
• W2088391621 workType "article" @default.