Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088392312> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2088392312 endingPage "O30" @default.
- W2088392312 startingPage "O30" @default.
- W2088392312 abstract "7-11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK Co-infections with HCV and HIV are common, because both viruses share routes of transmission and establish chronic infections. The standard treatment for chronic hepatitis C, a combination of peginterferon-α and ribavirin, is poorly tolerated and only successful in about half of the treated patients. Thus, identification of accurate predictors of treatment response is highly desirable. Several independent genome-wide association studies have recently identified human genetic variants around the IL28B gene (coding for IFN-λ3) that strongly associate with spontaneous clearance of HCV and with treatment success, both in HCV mono-infected and in co-infected patients. I will put these findings in perspective and discuss their practical and theoretical implications with regard to drug development, clinical trial design and clinical management of chronic HCV infection. Results of detailed genetic and functional analyses of the IL28B gene region will also be presented." @default.
- W2088392312 created "2016-06-24" @default.
- W2088392312 creator A5078153174 @default.
- W2088392312 date "2010-11-01" @default.
- W2088392312 modified "2023-09-24" @default.
- W2088392312 title "Host genetics of HCV disease - IL28B" @default.
- W2088392312 doi "https://doi.org/10.1186/1758-2652-13-s4-o30" @default.
- W2088392312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3112844" @default.
- W2088392312 hasPublicationYear "2010" @default.
- W2088392312 type Work @default.
- W2088392312 sameAs 2088392312 @default.
- W2088392312 citedByCount "0" @default.
- W2088392312 crossrefType "journal-article" @default.
- W2088392312 hasAuthorship W2088392312A5078153174 @default.
- W2088392312 hasBestOaLocation W20883923121 @default.
- W2088392312 hasConcept C104317684 @default.
- W2088392312 hasConcept C106208931 @default.
- W2088392312 hasConcept C126322002 @default.
- W2088392312 hasConcept C135763542 @default.
- W2088392312 hasConcept C153209595 @default.
- W2088392312 hasConcept C159047783 @default.
- W2088392312 hasConcept C203014093 @default.
- W2088392312 hasConcept C2522874641 @default.
- W2088392312 hasConcept C2776455275 @default.
- W2088392312 hasConcept C2780040827 @default.
- W2088392312 hasConcept C3020491458 @default.
- W2088392312 hasConcept C535046627 @default.
- W2088392312 hasConcept C54355233 @default.
- W2088392312 hasConcept C60644358 @default.
- W2088392312 hasConcept C71924100 @default.
- W2088392312 hasConcept C86803240 @default.
- W2088392312 hasConceptScore W2088392312C104317684 @default.
- W2088392312 hasConceptScore W2088392312C106208931 @default.
- W2088392312 hasConceptScore W2088392312C126322002 @default.
- W2088392312 hasConceptScore W2088392312C135763542 @default.
- W2088392312 hasConceptScore W2088392312C153209595 @default.
- W2088392312 hasConceptScore W2088392312C159047783 @default.
- W2088392312 hasConceptScore W2088392312C203014093 @default.
- W2088392312 hasConceptScore W2088392312C2522874641 @default.
- W2088392312 hasConceptScore W2088392312C2776455275 @default.
- W2088392312 hasConceptScore W2088392312C2780040827 @default.
- W2088392312 hasConceptScore W2088392312C3020491458 @default.
- W2088392312 hasConceptScore W2088392312C535046627 @default.
- W2088392312 hasConceptScore W2088392312C54355233 @default.
- W2088392312 hasConceptScore W2088392312C60644358 @default.
- W2088392312 hasConceptScore W2088392312C71924100 @default.
- W2088392312 hasConceptScore W2088392312C86803240 @default.
- W2088392312 hasLocation W20883923121 @default.
- W2088392312 hasLocation W20883923122 @default.
- W2088392312 hasLocation W20883923123 @default.
- W2088392312 hasOpenAccess W2088392312 @default.
- W2088392312 hasPrimaryLocation W20883923121 @default.
- W2088392312 hasRelatedWork W2022365546 @default.
- W2088392312 hasRelatedWork W2036119394 @default.
- W2088392312 hasRelatedWork W2042116581 @default.
- W2088392312 hasRelatedWork W2067404011 @default.
- W2088392312 hasRelatedWork W2076131525 @default.
- W2088392312 hasRelatedWork W2122020610 @default.
- W2088392312 hasRelatedWork W2347142336 @default.
- W2088392312 hasRelatedWork W2411498497 @default.
- W2088392312 hasRelatedWork W4241926437 @default.
- W2088392312 hasRelatedWork W2771873057 @default.
- W2088392312 hasVolume "13" @default.
- W2088392312 isParatext "false" @default.
- W2088392312 isRetracted "false" @default.
- W2088392312 magId "2088392312" @default.
- W2088392312 workType "article" @default.