Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088398304> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2088398304 endingPage "415" @default.
- W2088398304 startingPage "408" @default.
- W2088398304 abstract "Pharmacological control of blood pressure is usually indicated during aortic cross-clamping (AXC). The aim of this study was to analyze the modulation by isoflurane (ISO), sodium nitroprusside (SNP) and milrinone (MIL) of the systemic circulatory responses to a standardized infra-renal AXC.Chloralose-anaesthetized pigs were exposed to AXC at control (no vasoactive drugs) and during the administration of each of the drugs.During control, AXC increased mean arterial pressure (MAP, 17 +/- 4%) and systemic vascular resistance (SVR, 27 +/- 7%), but induced no significant changes in cardiac output (CO), heart rate (HR), pulmonary arterial pressures, pulmonary vascular resistance or central venous pressure. Low-dose ISO (0.7%) and investigated doses of SNP and MIL did not significantly alter this response. High-dose ISO (1.4%, attenuated the AXC-induced increase in SVR, but not in MAP. All drugs decreased non-clamp MAP levels. Therefore, with low-dose ISO and with SNP or MIL, peak MAP during AXC was not significantly different from control non-clamp levels (i.e. prior to pharmacological or surgical interventions). High-dose ISO was associated with a MAP during AXC that was below control non-clamp levels.The objective that during AXC MAP should not exceed control non-clamp levels was achieveable by ISO, SNP or MIL. The modulating actions of the drugs on MAP during AXC were exerted mainly through reductions in non-clamp levels. This systemic hypotension was associated with decreased CO and SVR during ISO, and with decreased SVR and increased HR during SNP and MIL. Attenuation of the AXC-induced increase in SVR was produced only by 1.4% ISO." @default.
- W2088398304 created "2016-06-24" @default.
- W2088398304 creator A5014992113 @default.
- W2088398304 creator A5019709705 @default.
- W2088398304 creator A5021353667 @default.
- W2088398304 creator A5040556370 @default.
- W2088398304 creator A5057609975 @default.
- W2088398304 date "1996-04-01" @default.
- W2088398304 modified "2023-10-18" @default.
- W2088398304 title "Cardiovascular responses to experimental infra-renal aortic cross-clamping. Modulating effects of isoflurane, sodium nitroprusside and milrinone" @default.
- W2088398304 cites W1982674666 @default.
- W2088398304 cites W1986897777 @default.
- W2088398304 cites W1995446344 @default.
- W2088398304 cites W1996807206 @default.
- W2088398304 cites W2005565117 @default.
- W2088398304 cites W2012977854 @default.
- W2088398304 cites W2038068150 @default.
- W2088398304 cites W2044348533 @default.
- W2088398304 cites W2045059130 @default.
- W2088398304 cites W2055902440 @default.
- W2088398304 cites W2071120941 @default.
- W2088398304 cites W2073528804 @default.
- W2088398304 cites W2091991192 @default.
- W2088398304 cites W2118416395 @default.
- W2088398304 cites W2146242416 @default.
- W2088398304 cites W2165263117 @default.
- W2088398304 cites W4210950940 @default.
- W2088398304 cites W4237516337 @default.
- W2088398304 cites W4301434551 @default.
- W2088398304 cites W4317563852 @default.
- W2088398304 doi "https://doi.org/10.1111/j.1399-6576.1996.tb04461.x" @default.
- W2088398304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8738683" @default.
- W2088398304 hasPublicationYear "1996" @default.
- W2088398304 type Work @default.
- W2088398304 sameAs 2088398304 @default.
- W2088398304 citedByCount "6" @default.
- W2088398304 countsByYear W20883983042014 @default.
- W2088398304 crossrefType "journal-article" @default.
- W2088398304 hasAuthorship W2088398304A5014992113 @default.
- W2088398304 hasAuthorship W2088398304A5019709705 @default.
- W2088398304 hasAuthorship W2088398304A5021353667 @default.
- W2088398304 hasAuthorship W2088398304A5040556370 @default.
- W2088398304 hasAuthorship W2088398304A5057609975 @default.
- W2088398304 hasConcept C126322002 @default.
- W2088398304 hasConcept C127413603 @default.
- W2088398304 hasConcept C164705383 @default.
- W2088398304 hasConcept C178853913 @default.
- W2088398304 hasConcept C2776161997 @default.
- W2088398304 hasConcept C2776452961 @default.
- W2088398304 hasConcept C2776645727 @default.
- W2088398304 hasConcept C2777953023 @default.
- W2088398304 hasConcept C2779610285 @default.
- W2088398304 hasConcept C42219234 @default.
- W2088398304 hasConcept C519581460 @default.
- W2088398304 hasConcept C58245268 @default.
- W2088398304 hasConcept C71924100 @default.
- W2088398304 hasConcept C78519656 @default.
- W2088398304 hasConcept C84111939 @default.
- W2088398304 hasConcept C84393581 @default.
- W2088398304 hasConceptScore W2088398304C126322002 @default.
- W2088398304 hasConceptScore W2088398304C127413603 @default.
- W2088398304 hasConceptScore W2088398304C164705383 @default.
- W2088398304 hasConceptScore W2088398304C178853913 @default.
- W2088398304 hasConceptScore W2088398304C2776161997 @default.
- W2088398304 hasConceptScore W2088398304C2776452961 @default.
- W2088398304 hasConceptScore W2088398304C2776645727 @default.
- W2088398304 hasConceptScore W2088398304C2777953023 @default.
- W2088398304 hasConceptScore W2088398304C2779610285 @default.
- W2088398304 hasConceptScore W2088398304C42219234 @default.
- W2088398304 hasConceptScore W2088398304C519581460 @default.
- W2088398304 hasConceptScore W2088398304C58245268 @default.
- W2088398304 hasConceptScore W2088398304C71924100 @default.
- W2088398304 hasConceptScore W2088398304C78519656 @default.
- W2088398304 hasConceptScore W2088398304C84111939 @default.
- W2088398304 hasConceptScore W2088398304C84393581 @default.
- W2088398304 hasIssue "4" @default.
- W2088398304 hasLocation W20883983041 @default.
- W2088398304 hasLocation W20883983042 @default.
- W2088398304 hasOpenAccess W2088398304 @default.
- W2088398304 hasPrimaryLocation W20883983041 @default.
- W2088398304 hasRelatedWork W2022651435 @default.
- W2088398304 hasRelatedWork W2128445096 @default.
- W2088398304 hasRelatedWork W2159987582 @default.
- W2088398304 hasRelatedWork W2195513968 @default.
- W2088398304 hasRelatedWork W2285354716 @default.
- W2088398304 hasRelatedWork W2392249173 @default.
- W2088398304 hasRelatedWork W2469397725 @default.
- W2088398304 hasRelatedWork W2582971951 @default.
- W2088398304 hasRelatedWork W2977523330 @default.
- W2088398304 hasRelatedWork W2979617965 @default.
- W2088398304 hasVolume "40" @default.
- W2088398304 isParatext "false" @default.
- W2088398304 isRetracted "false" @default.
- W2088398304 magId "2088398304" @default.
- W2088398304 workType "article" @default.