FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088405783> ?p ?o ?g. }

• W2088405783 endingPage "70" @default.
• W2088405783 startingPage "65" @default.
• W2088405783 abstract "Purpose of review Extracellular matrix (ECM) has both structural and regulatory roles. This update reviews the representative recent developments in diverse aspects of ECM biology relevant to inflammation, tissue destruction, fibrosis, and regeneration. Recent findings Biological regulation by ECM is emerging as a major research area, driven by several new directions. Sensing of mechanical cues provided by ECM was found to be crucial in regulating cell differentiation. Transforming growth factor-β (TGF-β) is a pivotal agent in fibrosis and inflammation. A combination of structural biology and cell biology provided novel insights on the mechanisms of its activation by cellular traction and ECM. Improved understanding of how fibrillin microfibrils and associated proteins regulated TGF-β sequestration and activation was achieved by analysis of inherited connective tissue disorders having TGF-β dysregulation as an underlying pathologic mechanism. Insights on microRNA-mediated ECM regulation suggest a key role for miR-29, for which potential therapeutic roles are emerging. Advances in understanding the ECM turnover by proteinases provided novel insights on cell regulation and identified useful disease biomarkers. Summary As a crucial modulator of cell behavior, ECM has exceptionally strong relevance and translational implications for human disease, opening novel opportunities for mechanistic understanding of disease pathogenesis as well as treatment." @default.
• W2088405783 created "2016-06-24" @default.
• W2088405783 creator A5028694338 @default.
• W2088405783 creator A5064761253 @default.
• W2088405783 date "2013-01-01" @default.
• W2088405783 modified "2023-10-18" @default.
• W2088405783 title "The biology of the extracellular matrix" @default.
• W2088405783 cites W1964220623 @default.
• W2088405783 cites W1966501485 @default.
• W2088405783 cites W1969049128 @default.
• W2088405783 cites W1977914172 @default.
• W2088405783 cites W1980409139 @default.
• W2088405783 cites W1982265133 @default.
• W2088405783 cites W1988381381 @default.
• W2088405783 cites W1988576610 @default.
• W2088405783 cites W1988784569 @default.
• W2088405783 cites W2004715531 @default.
• W2088405783 cites W2005918147 @default.
• W2088405783 cites W2038313328 @default.
• W2088405783 cites W2051546365 @default.
• W2088405783 cites W2051816002 @default.
• W2088405783 cites W2052031900 @default.
• W2088405783 cites W2053442544 @default.
• W2088405783 cites W2055012867 @default.
• W2088405783 cites W2055035964 @default.
• W2088405783 cites W2065678781 @default.
• W2088405783 cites W2068145360 @default.
• W2088405783 cites W2073922218 @default.
• W2088405783 cites W2080949560 @default.
• W2088405783 cites W2091765669 @default.
• W2088405783 cites W2097862336 @default.
• W2088405783 cites W2103589970 @default.
• W2088405783 cites W2115182078 @default.
• W2088405783 cites W2120055234 @default.
• W2088405783 cites W2128810105 @default.
• W2088405783 cites W2129032853 @default.
• W2088405783 cites W2130568296 @default.
• W2088405783 cites W2141738357 @default.
• W2088405783 cites W2146104000 @default.
• W2088405783 cites W2150338395 @default.
• W2088405783 cites W2157523461 @default.
• W2088405783 cites W2158482287 @default.
• W2088405783 cites W2160390633 @default.
• W2088405783 cites W2169754078 @default.
• W2088405783 doi "https://doi.org/10.1097/bor.0b013e32835b137b" @default.
• W2088405783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3560377" @default.
• W2088405783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23143224" @default.
• W2088405783 hasPublicationYear "2013" @default.
• W2088405783 type Work @default.
• W2088405783 sameAs 2088405783 @default.
• W2088405783 citedByCount "112" @default.
• W2088405783 countsByYear W20884057832013 @default.
• W2088405783 countsByYear W20884057832014 @default.
• W2088405783 countsByYear W20884057832015 @default.
• W2088405783 countsByYear W20884057832016 @default.
• W2088405783 countsByYear W20884057832017 @default.
• W2088405783 countsByYear W20884057832018 @default.
• W2088405783 countsByYear W20884057832019 @default.
• W2088405783 countsByYear W20884057832020 @default.
• W2088405783 countsByYear W20884057832021 @default.
• W2088405783 countsByYear W20884057832022 @default.
• W2088405783 countsByYear W20884057832023 @default.
• W2088405783 crossrefType "journal-article" @default.
• W2088405783 hasAuthorship W2088405783A5028694338 @default.
• W2088405783 hasAuthorship W2088405783A5064761253 @default.
• W2088405783 hasBestOaLocation W20884057831 @default.
• W2088405783 hasConcept C104317684 @default.
• W2088405783 hasConcept C10854531 @default.
• W2088405783 hasConcept C118131993 @default.
• W2088405783 hasConcept C142724271 @default.
• W2088405783 hasConcept C145059251 @default.
• W2088405783 hasConcept C189165786 @default.
• W2088405783 hasConcept C203014093 @default.
• W2088405783 hasConcept C2776914184 @default.
• W2088405783 hasConcept C2778229498 @default.
• W2088405783 hasConcept C2780559512 @default.
• W2088405783 hasConcept C28328180 @default.
• W2088405783 hasConcept C54355233 @default.
• W2088405783 hasConcept C71924100 @default.
• W2088405783 hasConcept C86803240 @default.
• W2088405783 hasConcept C95444343 @default.
• W2088405783 hasConceptScore W2088405783C104317684 @default.
• W2088405783 hasConceptScore W2088405783C10854531 @default.
• W2088405783 hasConceptScore W2088405783C118131993 @default.
• W2088405783 hasConceptScore W2088405783C142724271 @default.
• W2088405783 hasConceptScore W2088405783C145059251 @default.
• W2088405783 hasConceptScore W2088405783C189165786 @default.
• W2088405783 hasConceptScore W2088405783C203014093 @default.
• W2088405783 hasConceptScore W2088405783C2776914184 @default.
• W2088405783 hasConceptScore W2088405783C2778229498 @default.
• W2088405783 hasConceptScore W2088405783C2780559512 @default.
• W2088405783 hasConceptScore W2088405783C28328180 @default.
• W2088405783 hasConceptScore W2088405783C54355233 @default.
• W2088405783 hasConceptScore W2088405783C71924100 @default.
• W2088405783 hasConceptScore W2088405783C86803240 @default.
• W2088405783 hasConceptScore W2088405783C95444343 @default.
• W2088405783 hasIssue "1" @default.
• W2088405783 hasLocation W20884057831 @default.

• next