Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088432845> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2088432845 endingPage "192" @default.
- W2088432845 startingPage "186" @default.
- W2088432845 abstract "The ontogeny of glutamine uptake by jejunal basolateral membrane vesicles (BLMV) was studied in suckling and weanling rats and the results were compared with adult rats. Glutamine uptake was found to represent a transport into an osmotically active space and not mere binding to the membrane surface. Temperature dependency indicated a carrier-mediated process with optimal pH of 7.0. Transport of glutamine was Na+ (out greater than in) gradient dependent with a distinct overshoot phenomenon. The magnitude of the overshoot was higher in suckling compared with weanling rats. The uptake kinetics and inhibition profile indicated the existence of two major transport pathways. A Na(+)-dependent system correlated with System A showed tolerance to System N and System ASC substrates, and a Na(+)-independent system similar to the classical L system that favors leucine and BCH. The Vmax for the Na(+)-dependent system was higher in suckling compared with weanling and adult rats. The Vmax for the Na(+)-dependent system was 0.86 +/- 0.17, 0.64 +/- 0.8, and 0.41 +/- 0.9 nmol.mg protein-1.10 sec-1 for suckling, weanling, and adult rats, respectively. The Vmax for the Na(+)-independent system was 0.68 +/- 0.08, 0.50 +/- 0.03, and 0.24 +/- 0.03 nmol.mg protein-1.10 sec-1 for suckling, weanling, and adult rats, respectively. We conclude that glutamine uptake undergoes developmental changes consistent with more activity and/or number of glutamine transporters during periods of active cellular proliferation and differentiation." @default.
- W2088432845 created "2016-06-24" @default.
- W2088432845 creator A5009414104 @default.
- W2088432845 creator A5075999111 @default.
- W2088432845 creator A5082242825 @default.
- W2088432845 date "1990-07-01" @default.
- W2088432845 modified "2023-10-14" @default.
- W2088432845 title "Developmental Changes in Glutamine Transport by Rat Jejunal Basolateral Membrane Vesicles" @default.
- W2088432845 cites W1487906855 @default.
- W2088432845 cites W1525820657 @default.
- W2088432845 cites W1592254411 @default.
- W2088432845 cites W1775749144 @default.
- W2088432845 cites W1988970110 @default.
- W2088432845 cites W2019889457 @default.
- W2088432845 cites W2023783903 @default.
- W2088432845 cites W2058669904 @default.
- W2088432845 cites W2076142922 @default.
- W2088432845 cites W2103004159 @default.
- W2088432845 cites W2111921447 @default.
- W2088432845 cites W2139210380 @default.
- W2088432845 doi "https://doi.org/10.3181/00379727-194-43076" @default.
- W2088432845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2356187" @default.
- W2088432845 hasPublicationYear "1990" @default.
- W2088432845 type Work @default.
- W2088432845 sameAs 2088432845 @default.
- W2088432845 citedByCount "8" @default.
- W2088432845 countsByYear W20884328452018 @default.
- W2088432845 crossrefType "journal-article" @default.
- W2088432845 hasAuthorship W2088432845A5009414104 @default.
- W2088432845 hasAuthorship W2088432845A5075999111 @default.
- W2088432845 hasAuthorship W2088432845A5082242825 @default.
- W2088432845 hasConcept C12554922 @default.
- W2088432845 hasConcept C126322002 @default.
- W2088432845 hasConcept C130316041 @default.
- W2088432845 hasConcept C134018914 @default.
- W2088432845 hasConcept C185592680 @default.
- W2088432845 hasConcept C2778433245 @default.
- W2088432845 hasConcept C2779349466 @default.
- W2088432845 hasConcept C39587587 @default.
- W2088432845 hasConcept C41625074 @default.
- W2088432845 hasConcept C515207424 @default.
- W2088432845 hasConcept C55493867 @default.
- W2088432845 hasConcept C57947595 @default.
- W2088432845 hasConcept C71924100 @default.
- W2088432845 hasConcept C86803240 @default.
- W2088432845 hasConceptScore W2088432845C12554922 @default.
- W2088432845 hasConceptScore W2088432845C126322002 @default.
- W2088432845 hasConceptScore W2088432845C130316041 @default.
- W2088432845 hasConceptScore W2088432845C134018914 @default.
- W2088432845 hasConceptScore W2088432845C185592680 @default.
- W2088432845 hasConceptScore W2088432845C2778433245 @default.
- W2088432845 hasConceptScore W2088432845C2779349466 @default.
- W2088432845 hasConceptScore W2088432845C39587587 @default.
- W2088432845 hasConceptScore W2088432845C41625074 @default.
- W2088432845 hasConceptScore W2088432845C515207424 @default.
- W2088432845 hasConceptScore W2088432845C55493867 @default.
- W2088432845 hasConceptScore W2088432845C57947595 @default.
- W2088432845 hasConceptScore W2088432845C71924100 @default.
- W2088432845 hasConceptScore W2088432845C86803240 @default.
- W2088432845 hasIssue "3" @default.
- W2088432845 hasLocation W20884328451 @default.
- W2088432845 hasLocation W20884328452 @default.
- W2088432845 hasOpenAccess W2088432845 @default.
- W2088432845 hasPrimaryLocation W20884328451 @default.
- W2088432845 hasRelatedWork W138483814 @default.
- W2088432845 hasRelatedWork W1567078587 @default.
- W2088432845 hasRelatedWork W171773225 @default.
- W2088432845 hasRelatedWork W1770133153 @default.
- W2088432845 hasRelatedWork W1962798628 @default.
- W2088432845 hasRelatedWork W2002301665 @default.
- W2088432845 hasRelatedWork W2020842736 @default.
- W2088432845 hasRelatedWork W2409541290 @default.
- W2088432845 hasRelatedWork W36624856 @default.
- W2088432845 hasRelatedWork W2255233491 @default.
- W2088432845 hasVolume "194" @default.
- W2088432845 isParatext "false" @default.
- W2088432845 isRetracted "false" @default.
- W2088432845 magId "2088432845" @default.
- W2088432845 workType "article" @default.