Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088491145> ?p ?o ?g. }
- W2088491145 endingPage "95" @default.
- W2088491145 startingPage "87" @default.
- W2088491145 abstract "Arrestins are signal transduction modulators that quench the activated state of receptors. X-arrestin (ARRX) is specifically expressed in the red-, green-, and blue-sensitive cone photoreceptors, and is most likely a modulator of cone phototransduction. The human gene for X-arrestin at Xcen–Xq22 has been shown to be ∼20 kb in size and to consist of 17 exons and 16 introns. The exons are generally small, including exon 16 of 10 bp, and are clustered into three groups, separated by the two largest introns. This gene structure is generally similar to that of S-antigen, the rod photoreceptor arrestin. There is remarkable similarity, however, among the individual exons between the two genes in that 10 of the exons are identical in size. The 5′ upstream region of the X-arrestin gene contains TATA and CAAT boxes, typical of genes expressed in a tissue-specific manner, in contrast to the S-antigen gene, which lacks these promoter sequences. The promoter elements, common to both the X-arrestin and S-antigen genes, include the Ret-1/PCE-1 (PCE-1-like in X-arrestin), CRX, and the thyroid hormone/retinoic acid-responsive sequences, the former two being present in a number of photoreceptor-expressed genes. Three CRX-binding elements, 15 bp apart, are present in a cluster. The common promoter elements between the cone-expressed genes, X-arrestin and color opsins, include the TATA box, PCE-1, and CRX-binding sequences, the combination of which might be important for directing cone-specific expression." @default.
- W2088491145 created "2016-06-24" @default.
- W2088491145 creator A5038710773 @default.
- W2088491145 creator A5039113744 @default.
- W2088491145 creator A5050790338 @default.
- W2088491145 creator A5056556901 @default.
- W2088491145 date "1998-12-01" @default.
- W2088491145 modified "2023-09-23" @default.
- W2088491145 title "Isolation and characterization of the human X-arrestin gene" @default.
- W2088491145 cites W1486226554 @default.
- W2088491145 cites W1498244267 @default.
- W2088491145 cites W1512108330 @default.
- W2088491145 cites W1602525846 @default.
- W2088491145 cites W1639540363 @default.
- W2088491145 cites W1896511711 @default.
- W2088491145 cites W1965863612 @default.
- W2088491145 cites W1969600436 @default.
- W2088491145 cites W1982498248 @default.
- W2088491145 cites W1990989603 @default.
- W2088491145 cites W1997514802 @default.
- W2088491145 cites W2012652285 @default.
- W2088491145 cites W2014669590 @default.
- W2088491145 cites W2016537683 @default.
- W2088491145 cites W2019875735 @default.
- W2088491145 cites W2025692747 @default.
- W2088491145 cites W2037824747 @default.
- W2088491145 cites W2038055250 @default.
- W2088491145 cites W2042963179 @default.
- W2088491145 cites W2059344357 @default.
- W2088491145 cites W2060207881 @default.
- W2088491145 cites W2060333964 @default.
- W2088491145 cites W2063450941 @default.
- W2088491145 cites W2065707503 @default.
- W2088491145 cites W2072414883 @default.
- W2088491145 cites W2076813807 @default.
- W2088491145 cites W2078952292 @default.
- W2088491145 cites W2080269085 @default.
- W2088491145 cites W2082108183 @default.
- W2088491145 cites W2084118479 @default.
- W2088491145 cites W2100726754 @default.
- W2088491145 cites W2106524519 @default.
- W2088491145 cites W2122385641 @default.
- W2088491145 cites W2138270253 @default.
- W2088491145 cites W388190409 @default.
- W2088491145 doi "https://doi.org/10.1016/s0378-1119(98)00510-1" @default.
- W2088491145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9931451" @default.
- W2088491145 hasPublicationYear "1998" @default.
- W2088491145 type Work @default.
- W2088491145 sameAs 2088491145 @default.
- W2088491145 citedByCount "24" @default.
- W2088491145 countsByYear W20884911452013 @default.
- W2088491145 countsByYear W20884911452014 @default.
- W2088491145 countsByYear W20884911452015 @default.
- W2088491145 countsByYear W20884911452016 @default.
- W2088491145 countsByYear W20884911452017 @default.
- W2088491145 countsByYear W20884911452020 @default.
- W2088491145 countsByYear W20884911452022 @default.
- W2088491145 countsByYear W20884911452023 @default.
- W2088491145 crossrefType "journal-article" @default.
- W2088491145 hasAuthorship W2088491145A5038710773 @default.
- W2088491145 hasAuthorship W2088491145A5039113744 @default.
- W2088491145 hasAuthorship W2088491145A5050790338 @default.
- W2088491145 hasAuthorship W2088491145A5056556901 @default.
- W2088491145 hasBestOaLocation W20884911451 @default.
- W2088491145 hasConcept C101762097 @default.
- W2088491145 hasConcept C104317684 @default.
- W2088491145 hasConcept C131667965 @default.
- W2088491145 hasConcept C135285700 @default.
- W2088491145 hasConcept C150194340 @default.
- W2088491145 hasConcept C153911025 @default.
- W2088491145 hasConcept C2777503648 @default.
- W2088491145 hasConcept C2780827179 @default.
- W2088491145 hasConcept C36823959 @default.
- W2088491145 hasConcept C54355233 @default.
- W2088491145 hasConcept C55493867 @default.
- W2088491145 hasConcept C62478195 @default.
- W2088491145 hasConcept C65888428 @default.
- W2088491145 hasConcept C86803240 @default.
- W2088491145 hasConcept C94671646 @default.
- W2088491145 hasConceptScore W2088491145C101762097 @default.
- W2088491145 hasConceptScore W2088491145C104317684 @default.
- W2088491145 hasConceptScore W2088491145C131667965 @default.
- W2088491145 hasConceptScore W2088491145C135285700 @default.
- W2088491145 hasConceptScore W2088491145C150194340 @default.
- W2088491145 hasConceptScore W2088491145C153911025 @default.
- W2088491145 hasConceptScore W2088491145C2777503648 @default.
- W2088491145 hasConceptScore W2088491145C2780827179 @default.
- W2088491145 hasConceptScore W2088491145C36823959 @default.
- W2088491145 hasConceptScore W2088491145C54355233 @default.
- W2088491145 hasConceptScore W2088491145C55493867 @default.
- W2088491145 hasConceptScore W2088491145C62478195 @default.
- W2088491145 hasConceptScore W2088491145C65888428 @default.
- W2088491145 hasConceptScore W2088491145C86803240 @default.
- W2088491145 hasConceptScore W2088491145C94671646 @default.
- W2088491145 hasIssue "1-2" @default.
- W2088491145 hasLocation W20884911451 @default.
- W2088491145 hasLocation W20884911452 @default.
- W2088491145 hasOpenAccess W2088491145 @default.