FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088509045> ?p ?o ?g. }

• W2088509045 endingPage "24" @default.
• W2088509045 startingPage "17" @default.
• W2088509045 abstract "The emergence of bovine spongiform encephalopathy (BSE) in cattle and, subsequently, its transmission to humans resulting in variant Creutzfeldt-Jakob disease (vCJD) in the UK has proved to be one of the major public health scares of the century. The oral route of infection, the long incubation period, and the incredible resistance of the transmissible infectious agent to various forms of decontamination poses unique challenges. Fortunately, despite extensive exposure of the UK population to contaminated meat, the size of the vCJD epidemic that has emerged since its initial detection is relatively low (225 worldwide). An explanation for this disparity is as yet incomplete, but the development of the disease is likely influenced by a number of factors including physical properties of the infectious agent, environmental factors such as the route and amount of exposure and individual susceptibility factors. This review focuses on current knowledge of the genetic factors that undoubtedly play a major role in influencing the development of vCJD. In terms of genetic susceptibility, the best characterised is the common single nucleotide polymorphism at codon 129 of the human prion protein gene (PRNP). Moreover, several other polymorphisms and mutations have been identified that may affect susceptibility as well as other important disease characteristics such as the highly variable prion disease incubation period." @default.
• W2088509045 created "2016-06-24" @default.
• W2088509045 creator A5003718692 @default.
• W2088509045 creator A5021639890 @default.
• W2088509045 date "2013-01-01" @default.
• W2088509045 modified "2023-10-12" @default.
• W2088509045 title "The Genetics of Susceptibility to Variant Creutzfeldt-Jakob Disease" @default.
• W2088509045 cites W1577439954 @default.
• W2088509045 cites W1638331785 @default.
• W2088509045 cites W1836242379 @default.
• W2088509045 cites W1970274267 @default.
• W2088509045 cites W1970306306 @default.
• W2088509045 cites W1972777213 @default.
• W2088509045 cites W1982409119 @default.
• W2088509045 cites W1987924754 @default.
• W2088509045 cites W1989150559 @default.
• W2088509045 cites W1990924713 @default.
• W2088509045 cites W2005200706 @default.
• W2088509045 cites W2013679718 @default.
• W2088509045 cites W2025546736 @default.
• W2088509045 cites W2030103154 @default.
• W2088509045 cites W2041571977 @default.
• W2088509045 cites W2042978244 @default.
• W2088509045 cites W2045562971 @default.
• W2088509045 cites W2046090380 @default.
• W2088509045 cites W2047225722 @default.
• W2088509045 cites W2048041842 @default.
• W2088509045 cites W2051409625 @default.
• W2088509045 cites W2055463834 @default.
• W2088509045 cites W2069200966 @default.
• W2088509045 cites W2072142219 @default.
• W2088509045 cites W2076146345 @default.
• W2088509045 cites W2082573664 @default.
• W2088509045 cites W2089215677 @default.
• W2088509045 cites W2089589220 @default.
• W2088509045 cites W2089626188 @default.
• W2088509045 cites W2092823638 @default.
• W2088509045 cites W2097577051 @default.
• W2088509045 cites W2097646688 @default.
• W2088509045 cites W2112140556 @default.
• W2088509045 cites W2120350230 @default.
• W2088509045 cites W2121611717 @default.
• W2088509045 cites W2122056682 @default.
• W2088509045 cites W2123705849 @default.
• W2088509045 cites W2125346686 @default.
• W2088509045 cites W2130547480 @default.
• W2088509045 cites W2131082569 @default.
• W2088509045 cites W2131317082 @default.
• W2088509045 cites W2133365762 @default.
• W2088509045 cites W2135292352 @default.
• W2088509045 cites W2137288103 @default.
• W2088509045 cites W2139131583 @default.
• W2088509045 cites W2140600907 @default.
• W2088509045 cites W2143113093 @default.
• W2088509045 cites W2145922265 @default.
• W2088509045 cites W2148029908 @default.
• W2088509045 cites W2150254407 @default.
• W2088509045 cites W2152360214 @default.
• W2088509045 cites W2154758277 @default.
• W2088509045 cites W2324660492 @default.
• W2088509045 doi "https://doi.org/10.1159/000345203" @default.
• W2088509045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23548713" @default.
• W2088509045 hasPublicationYear "2013" @default.
• W2088509045 type Work @default.
• W2088509045 sameAs 2088509045 @default.
• W2088509045 citedByCount "15" @default.
• W2088509045 countsByYear W20885090452014 @default.
• W2088509045 countsByYear W20885090452015 @default.
• W2088509045 countsByYear W20885090452016 @default.
• W2088509045 countsByYear W20885090452017 @default.
• W2088509045 countsByYear W20885090452018 @default.
• W2088509045 countsByYear W20885090452020 @default.
• W2088509045 countsByYear W20885090452021 @default.
• W2088509045 countsByYear W20885090452023 @default.
• W2088509045 crossrefType "journal-article" @default.
• W2088509045 hasAuthorship W2088509045A5003718692 @default.
• W2088509045 hasAuthorship W2088509045A5021639890 @default.
• W2088509045 hasBestOaLocation W20885090451 @default.
• W2088509045 hasConcept C104317684 @default.
• W2088509045 hasConcept C135763542 @default.
• W2088509045 hasConcept C142724271 @default.
• W2088509045 hasConcept C143701427 @default.
• W2088509045 hasConcept C159047783 @default.
• W2088509045 hasConcept C25642318 @default.
• W2088509045 hasConcept C2776735649 @default.
• W2088509045 hasConcept C2776797465 @default.
• W2088509045 hasConcept C2778147599 @default.
• W2088509045 hasConcept C2779134260 @default.
• W2088509045 hasConcept C2781131914 @default.
• W2088509045 hasConcept C2908647359 @default.
• W2088509045 hasConcept C2992046845 @default.
• W2088509045 hasConcept C3019804061 @default.
• W2088509045 hasConcept C54355233 @default.
• W2088509045 hasConcept C55493867 @default.
• W2088509045 hasConcept C67636389 @default.
• W2088509045 hasConcept C71924100 @default.
• W2088509045 hasConcept C86803240 @default.
• W2088509045 hasConcept C99454951 @default.

• next