Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088540774> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2088540774 endingPage "30" @default.
- W2088540774 startingPage "19" @default.
- W2088540774 abstract "A new human Ewing's sarcoma cell line (CADO-ES1) was established from the malignant pleural effusion of a 19-year-old woman. These cells grew both anchorage dependently and anchorage independently. When cultured in bacteriologic dishes, they grew as tightly packed multicellular tumor spheroids; they were also capable of proliferating in soft agar. Flow cytometric DNA analysis demonstrated a nearly diploid DNA content (DNA index = 0.902). Chromosomal studies of cultured cells showed an isodicentric chromosome 8 in all examined cells, but t(11;22)(q24;q12), a translocation reported previously in Ewing's sarcoma, was not detected. Under normal culture conditions, no morphologic evidence of neural differentiation was detected. In addition, immunocytochemical studies showed that vimentin was intensely positive, whereas neurofilament (NF) and neuron-specific enolase (NSE) were weakly positive. Treatment with cyclic AMP (cAMP) induced pronounced morphologic evidence of neural differentiation and strong expression of NF in cultured cells. S-100 protein, glial fibrillary acidic protein (GFAP), desmin, cytokeratin, and epithelial membrane antigen were not detected immunohistochemically in either untreated or cAMP-treated cells, however. These data suggest that this cell line is derived from a highly undifferentiated neural cell with high chromosomal clonality, differentiating into neural features under certain conditions." @default.
- W2088540774 created "2016-06-24" @default.
- W2088540774 creator A5010539915 @default.
- W2088540774 creator A5027824206 @default.
- W2088540774 creator A5029531503 @default.
- W2088540774 creator A5047900853 @default.
- W2088540774 creator A5076968285 @default.
- W2088540774 creator A5081508610 @default.
- W2088540774 creator A5091248337 @default.
- W2088540774 creator A5091531215 @default.
- W2088540774 date "1991-11-01" @default.
- W2088540774 modified "2023-09-23" @default.
- W2088540774 title "Establishment and characterization of a new Ewing's sarcoma cell line" @default.
- W2088540774 cites W1972973069 @default.
- W2088540774 cites W1973633502 @default.
- W2088540774 cites W1993757818 @default.
- W2088540774 cites W2011109664 @default.
- W2088540774 cites W2026853588 @default.
- W2088540774 cites W2031900656 @default.
- W2088540774 cites W2056810337 @default.
- W2088540774 cites W2063943183 @default.
- W2088540774 cites W2067708781 @default.
- W2088540774 cites W2068402552 @default.
- W2088540774 cites W2418408277 @default.
- W2088540774 doi "https://doi.org/10.1016/0165-4608(91)90185-w" @default.
- W2088540774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1756482" @default.
- W2088540774 hasPublicationYear "1991" @default.
- W2088540774 type Work @default.
- W2088540774 sameAs 2088540774 @default.
- W2088540774 citedByCount "22" @default.
- W2088540774 countsByYear W20885407742016 @default.
- W2088540774 countsByYear W20885407742018 @default.
- W2088540774 countsByYear W20885407742019 @default.
- W2088540774 countsByYear W20885407742020 @default.
- W2088540774 countsByYear W20885407742022 @default.
- W2088540774 countsByYear W20885407742023 @default.
- W2088540774 crossrefType "journal-article" @default.
- W2088540774 hasAuthorship W2088540774A5010539915 @default.
- W2088540774 hasAuthorship W2088540774A5027824206 @default.
- W2088540774 hasAuthorship W2088540774A5029531503 @default.
- W2088540774 hasAuthorship W2088540774A5047900853 @default.
- W2088540774 hasAuthorship W2088540774A5076968285 @default.
- W2088540774 hasAuthorship W2088540774A5081508610 @default.
- W2088540774 hasAuthorship W2088540774A5091248337 @default.
- W2088540774 hasAuthorship W2088540774A5091531215 @default.
- W2088540774 hasConcept C142724271 @default.
- W2088540774 hasConcept C147447768 @default.
- W2088540774 hasConcept C153911025 @default.
- W2088540774 hasConcept C157207234 @default.
- W2088540774 hasConcept C188618488 @default.
- W2088540774 hasConcept C203014093 @default.
- W2088540774 hasConcept C204232928 @default.
- W2088540774 hasConcept C2778256501 @default.
- W2088540774 hasConcept C2779012181 @default.
- W2088540774 hasConcept C2779072444 @default.
- W2088540774 hasConcept C2780495277 @default.
- W2088540774 hasConcept C54355233 @default.
- W2088540774 hasConcept C71924100 @default.
- W2088540774 hasConcept C81885089 @default.
- W2088540774 hasConcept C86803240 @default.
- W2088540774 hasConceptScore W2088540774C142724271 @default.
- W2088540774 hasConceptScore W2088540774C147447768 @default.
- W2088540774 hasConceptScore W2088540774C153911025 @default.
- W2088540774 hasConceptScore W2088540774C157207234 @default.
- W2088540774 hasConceptScore W2088540774C188618488 @default.
- W2088540774 hasConceptScore W2088540774C203014093 @default.
- W2088540774 hasConceptScore W2088540774C204232928 @default.
- W2088540774 hasConceptScore W2088540774C2778256501 @default.
- W2088540774 hasConceptScore W2088540774C2779012181 @default.
- W2088540774 hasConceptScore W2088540774C2779072444 @default.
- W2088540774 hasConceptScore W2088540774C2780495277 @default.
- W2088540774 hasConceptScore W2088540774C54355233 @default.
- W2088540774 hasConceptScore W2088540774C71924100 @default.
- W2088540774 hasConceptScore W2088540774C81885089 @default.
- W2088540774 hasConceptScore W2088540774C86803240 @default.
- W2088540774 hasIssue "1" @default.
- W2088540774 hasLocation W20885407741 @default.
- W2088540774 hasLocation W20885407742 @default.
- W2088540774 hasOpenAccess W2088540774 @default.
- W2088540774 hasPrimaryLocation W20885407741 @default.
- W2088540774 hasRelatedWork W1247724174 @default.
- W2088540774 hasRelatedWork W2059896428 @default.
- W2088540774 hasRelatedWork W2065322239 @default.
- W2088540774 hasRelatedWork W2076353195 @default.
- W2088540774 hasRelatedWork W2104399094 @default.
- W2088540774 hasRelatedWork W2161384328 @default.
- W2088540774 hasRelatedWork W2162663678 @default.
- W2088540774 hasRelatedWork W2411638288 @default.
- W2088540774 hasRelatedWork W2417199195 @default.
- W2088540774 hasRelatedWork W2418005520 @default.
- W2088540774 hasVolume "57" @default.
- W2088540774 isParatext "false" @default.
- W2088540774 isRetracted "false" @default.
- W2088540774 magId "2088540774" @default.
- W2088540774 workType "article" @default.